Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Pimagedine"'
Akademický článek
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Publikováno v:
Journal of Mazandaran University of Medical Sciences, Vol 29, Iss 172, Pp 127-134 (2019)
Background and purpose: Hepatocellular carcinoma (HCC) is one of the most fatal cancers, so, proposing new anticancer agents is highly valuable. Production of reactive oxygen species (ROS) is increased in majority of cancers. Increase in ROS leads to
Externí odkaz:
https://doaj.org/article/a4f819e7d66b496baadab1c6368260a5
Akademický článek
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Autor:
Antonio Nenna, Francesco Nappi, Sanjeet Singh Avtaar Singh, Fraser W Sutherland, Fabio Di Domenico, Massimo Chello, Cristiano Spadaccio
Publikováno v:
Research in Cardiovascular Medicine, Vol 4, Iss 2, Pp 5-5 (2015)
Context: Advanced Glycation End-Products (AGEs) are signaling proteins associated to several vascular and neurological complications in diabetic and non-diabetic patients. AGEs proved to be a marker of negative outcome in both diabetes management and
Externí odkaz:
https://doaj.org/article/c0cfdc6fa0f543eb813e1c5552a5cebc
Autor:
Petra Dvorakova, Jan Vacek, Marika Svrckova, Dominika Coufalová, David Novak, Lenka Hernychova, Martina Zatloukalová
Publikováno v:
Free Radical Biology and Medicine. 108:146-154
Proteins are subject to oxidative modification and the formation of adducts with a broad spectrum of reactive species via enzymatic and non-enzymatic mechanisms. Here we report that in vitro non-enzymatic methylglyoxal (MGO) binding causes the inhibi
Akademický článek
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Autor:
D. Ebel, Markus W. Hollmann, Ragnar Huhn, Wolfgang Schlack, Nina C. Weber, Benedikt Preckel, Jan Fräßdorf, Nadja Wingert, O. Toma
Publikováno v:
Anesthesiology. 113:1289-1298
Background Sevoflurane induces preconditioning (SevoPC). The effect of aprotinin and the involvement of endothelial nitric-oxide synthase (NOS) on SevoPC are unknown. We investigated (1) whether SevoPC is strengthened by multiple preconditioning cycl
Publikováno v:
Neuro-Oncology. 13:203-211
Nitric oxide (NO) signaling in tumors and endothelial cells regulates vascular permeability and blood flow and therefore influences tumor uptake and response to therapeutic compounds. As delivery and efficacy of chemotherapy is impaired in CNS neopla
Publikováno v:
Chest. 135:353-367
Background Nitric oxide (NO) is produced by resident and inflammatory cells in the respiratory tract by the enzyme NO synthase (NOS), which exists in three isoforms: neuronal NOS (nNOS), inducible NOS (iNOS), and endothelial NOS. NO production is inc
Publikováno v:
Recent patents on cardiovascular drug discovery (2015).
info:cnr-pdr/source/autori:Nenna A, Spadaccio C, Lusini M, Ulianich L, Chello M, Nappi F/titolo:Basic and clinical research against Advanced Glycation End Products (AGEs): new compounds to tackle cardiovascular disease and diabetic complications/doi:/rivista:Recent patents on cardiovascular drug discovery/anno:2015/pagina_da:/pagina_a:/intervallo_pagine:/volume
info:cnr-pdr/source/autori:Nenna A, Spadaccio C, Lusini M, Ulianich L, Chello M, Nappi F/titolo:Basic and clinical research against Advanced Glycation End Products (AGEs): new compounds to tackle cardiovascular disease and diabetic complications/doi:/rivista:Recent patents on cardiovascular drug discovery/anno:2015/pagina_da:/pagina_a:/intervallo_pagine:/volume
Diabetes is a major risk factor for cardiovascular disease, and recent advances in research indicate that a detailed understanding of the pathophysiology of its effects is mandatory to reduce diabetes-related mortality and morbidity. Advanced Glycati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=cnr_________::9a013b80901b8b8a8401f1a4d502d634
https://publications.cnr.it/doc/336593
https://publications.cnr.it/doc/336593