Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Pilvi Maliniemi"'
Autor:
Olga Bugaeva, Pilvi Maliniemi, Wenche S. Prestvik, Eeva Leivo, Nicolas Kluger, Alexander Salava, Sanna Virtanen, Kirsi Jäntti, Olli Saksela, Kaisa Lehti, Paula Kujala, Kaj Krohn, Annamari Ranki
Publikováno v:
Acta Dermato-Venereologica, Vol 103 (2023)
Melanoma is a highly metastatic tumour originating from neural crest-derived melanocytes. The aim of this study was to analyse the expression of neuron navigator 3 (NAV3) in relation to membrane type-1 matrix metalloproteinase MMP14, a major regulato
Externí odkaz:
https://doaj.org/article/be93bcaba81f463c88d6229ed9d2ea83
Autor:
Farhana Jahan, Jan Koski, Diana Schenkwein, Seppo Ylä-Herttuala, Helka Göös, Sini Huuskonen, Markku Varjosalo, Pilvi Maliniemi, Judith Leitner, Peter Steinberger, Hans-Jörg Bühring, Kim Vettenranta, Matti Korhonen
Publikováno v:
Frontiers in Molecular Medicine, Vol 3 (2023)
Background: T cells that are genetically modified with chimeric antigen receptor (CAR) hold promise for immunotherapy of cancer. Currently, there are intense efforts to improve the safety and efficacy of CAR T cell therapies against liquid and solid
Externí odkaz:
https://doaj.org/article/99b6cf95a3c24eb697aeaeaaf665b268
Autor:
Jan Koski, Farhana Jahan, Annu Luostarinen, Diana Schenkwein, Seppo Ylä-Herttuala, Helka Göös, Hector Monzo, Päivi M. Ojala, Pilvi Maliniemi, Matti Korhonen
Publikováno v:
Frontiers in Molecular Medicine, Vol 2 (2022)
Background: T cells equipped with chimeric antigen receptors (CAR) have shown remarkable efficacy in targeting B lineage malignancies. Improvement of the CAR structure is needed, however, with a view to developing flexibly modifiable spacers that are
Externí odkaz:
https://doaj.org/article/3970041dcbc24907a9291c98de9f005e
Autor:
Kaisa Lehti, Jorma Keski-Oja, Päivi M. Ojala, Annamari Ranki, Kari Alitalo, Sampsa Hautaniemi, Ville Rantanen, Jouko Lohi, Pilvi Maliniemi, Pauliina Repo, Riku Louhimo, Tanja Holopainen, Pirita Pekkonen, Erika Gucciardo, Olga Tatti
Supplementary Tables S1-S4. MMPs which are significantly over-expressed in melanoma cell lines compared to the mean expression of all cancer cell lines in the datasets with over 15 melanoma cell lines (S1); Outlier analysis of MMP16 copy number gain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c7e98651081946cdd8bfdac15223cd
https://doi.org/10.1158/0008-5472.22404674
https://doi.org/10.1158/0008-5472.22404674
Autor:
Kaisa Lehti, Jorma Keski-Oja, Päivi M. Ojala, Annamari Ranki, Kari Alitalo, Sampsa Hautaniemi, Ville Rantanen, Jouko Lohi, Pilvi Maliniemi, Pauliina Repo, Riku Louhimo, Tanja Holopainen, Pirita Pekkonen, Erika Gucciardo, Olga Tatti
Supplementary Data. Supplementary Materials and Methods and Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de16af2dab751c57fb9d7db94af2d4e
https://doi.org/10.1158/0008-5472.22404686.v1
https://doi.org/10.1158/0008-5472.22404686.v1
Autor:
Kaisa Lehti, Jorma Keski-Oja, Päivi M. Ojala, Annamari Ranki, Kari Alitalo, Sampsa Hautaniemi, Ville Rantanen, Jouko Lohi, Pilvi Maliniemi, Pauliina Repo, Riku Louhimo, Tanja Holopainen, Pirita Pekkonen, Erika Gucciardo, Olga Tatti
Supplementary Figures S1-S9. MMP14 which is over-expressed in melanoma cell lines was not associated with patient survival (S1); Vasculature and morphology of human melanoma tumors (S2); MMP16 expression in WM852 cells and its correlation with tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3f3780163302e48356405ab0c71f2c
https://doi.org/10.1158/0008-5472.22404680.v1
https://doi.org/10.1158/0008-5472.22404680.v1
Autor:
Pilvi Maliniemi, Kirsi Laukkanen, Liisa Väkevä, Katja Dettmer, Tuomas Lipsanen, Leila Jeskanen, Alban Bessede, Peter J. Oefner, Marshall E. Kadin, Annamari Ranki
Publikováno v:
OncoImmunology, Vol 6, Iss 3 (2017)
Indoleamine 2,3-deoxygenase 1 (IDO1) induces immune tolerance in the tumor microenvironment (TME) and is recognized as a potential therapeutic target. We studied the expression of both IDO1 and the related tryptophan 2,3-dioxygenase (TDO) in several
Externí odkaz:
https://doaj.org/article/b1272afb72c74acf83ede93bd1fdc028
Autor:
Helena Hohtari, Judith Leitner, Pekka Ellonen, Tero Aittokallio, Satu Mustjoki, Matti Korhonen, Khalid Saeed, Pilvi Maliniemi, Tiina Hannunen, Peter Steinberger, Jan Koski, Mikko Antti Ilmari Keränen, Aleksandr Ianevski, Petri Pölönen, Matti Kankainen, Olli Dufva, Jay Klievink
Publikováno v:
Blood. 135:597-609
Funding Information: The authors thank Laura Turunen, Jani Saarela, Katja Suomi, and Maria Nurmi of the High-Throughput Biomedicine Unit and the personnel of the Sequencing Laboratory at the Institute of Molecular Medicine Finland. The authors also t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20992c0de36ff892c0d02f601e3f99ba
https://doi.org/10.1182/blood.2019002121
https://doi.org/10.1182/blood.2019002121
Autor:
Pilvi Maliniemi, Michelle Vincendeau, Jens Mayer, Oliver Frank, Sonja Hahtola, Leena Karenko, Emilia Carlsson, Francois Mallet, Wolfgang Seifarth, Christine Leib-Mösch, Annamari Ranki
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76281 (2013)
The pathomechanism of mycosis fungoides (MF), the most common type of primary cutaneous T-cell lymphomas (CTCLs) and a malignancy of non-recirculating, skin-resident T-cells, is unknown albeit underlying viral infections have been sought for. Human e
Externí odkaz:
https://doaj.org/article/e09f8b448d89417c8ca081205514a479
Autor:
Tanja Kaartinen, Annu Luostarinen, Pilvi Maliniemi, Joni Keto, Mikko Arvas, Heini Belt, Jonna Koponen, Petri I. Mäkinen, Angelica Loskog, Satu Mustjoki, Kimmo Porkka, Seppo Ylä-Herttuala, Matti Korhonen
Publikováno v:
Cytotherapy. 19(9)
Background Adoptive T-cell therapy offers new options for cancer treatment. Clinical results suggest that T-cell persistence, depending on T-cell memory, improves efficacy. The use of interleukin (IL)-2 for in vitro T-cell expansion is not straightfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f19169e764e8d75feea15befbdf17b
https://pubmed.ncbi.nlm.nih.gov/28411126
https://pubmed.ncbi.nlm.nih.gov/28411126