Severe Thrombocytopenia and Platelet Granule Dysfunction Associated with the Combination of Novel Heterozygous Variants in TUBB1 and ITGB3.

Autor: Pillitteri, D., Sollfrank, S., Althaus, K., Heine, S., Lackner, K., Bakchoul, T., Rossmann, H., Krause, M., Jurk, K.

Publikováno v: Hämostaseologie; 2019 Supplement, Vol. 39, pS1-S92, 92p

CD36-fibrin interaction propagates FXI-dependent thrombin generation of human platelets.

Autor: Döhrmann M; Center for Thrombosis and Hemostasis (CTH), University Medical Center, Johannes Gutenberg-University Mainz, Mainz, Germany., Makhoul S; Center for Thrombosis and Hemostasis (CTH), University Medical Center, Johannes Gutenberg-University Mainz, Mainz, Germany., Gross K; Center for Thrombosis and Hemostasis (CTH), University Medical Center, Johannes Gutenberg-University Mainz, Mainz, Germany., Krause M; Deutsche Klinik für Diagnostik HELIOS Klinik, Wiesbaden, Germany., Pillitteri D; Deutsche Klinik für Diagnostik HELIOS Klinik, Wiesbaden, Germany., von Auer C; Third Department of Medicine, University Medical Center, Johannes Gutenberg-University Mainz, Mainz, Germany., Walter U; Center for Thrombosis and Hemostasis (CTH), University Medical Center, Johannes Gutenberg-University Mainz, Mainz, Germany., Lutz J; Section of Nephrology, I. Department of Medicine, University Medical Center, Johannes Gutenberg-University Mainz, Mainz, Germany.; Medical Clinic, Section of Nephrology and Infectious Diseases, Gemeinschaftsklinikum Mittelrhein, Koblenz, Germany., Volf I; Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria., Kehrel BE; Department of Anesthesiology, Intensive Care and Pain Medicine, Experimental and Clinical Hemostasis, University of Muenster, Muenster, Germany., Jurk K; Center for Thrombosis and Hemostasis (CTH), University Medical Center, Johannes Gutenberg-University Mainz, Mainz, Germany.; Department of Anesthesiology, Intensive Care and Pain Medicine, Experimental and Clinical Hemostasis, University of Muenster, Muenster, Germany.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2020 Jul; Vol. 34 (7), pp. 9337-9357. Date of Electronic Publication: 2020 May 28.

High-throughput elucidation of thrombus formation reveals sources of platelet function variability.

Autor: van Geffen JP; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands., Brouns SLN; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands., Batista J; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK.; National Health Service Blood and Transplant (NHSBT), Cambridge Biomedical Campus, UK., McKinney H; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK.; National Health Service Blood and Transplant (NHSBT), Cambridge Biomedical Campus, UK., Kempster C; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK.; National Health Service Blood and Transplant (NHSBT), Cambridge Biomedical Campus, UK., Nagy M; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands., Sivapalaratnam S; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK.; The Royal London Haemophilia Centre, London, UK., Baaten CCFMJ; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands., Bourry N; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands., Frontini M; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK.; National Health Service Blood and Transplant (NHSBT), Cambridge Biomedical Campus, UK.; BHF Centre of Excellence, Division of Cardiovascular Medicine, Cambridge University Hospitals, Cambridge Biomedical Campus, UK., Jurk K; Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University Mainz, Germany., Krause M; DKD Helios Klinik Wiesbaden, Germany., Pillitteri D; DKD Helios Klinik Wiesbaden, Germany., Swieringa F; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands., Verdoold R; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands., Cavill R; Department of Data Science & Knowledge Engineering, Faculty of Humanities and Sciences, Maastricht University, the Netherlands., Kuijpers MJE; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands., Ouwehand WH; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK.; National Health Service Blood and Transplant (NHSBT), Cambridge Biomedical Campus, UK.; BHF Centre of Excellence, Division of Cardiovascular Medicine, Cambridge University Hospitals, Cambridge Biomedical Campus, UK.; NIHR BioResource, University of Cambridge, Cambridge Biomedical Campus, UK.; Department of Human Genetics, The Wellcome Sanger Institute, Hinxton, Cambridge, UK., Downes K; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, UK jwm.heemskerk@maastrichtuniversity.nl kd286@cam.ac.uk.; National Health Service Blood and Transplant (NHSBT), Cambridge Biomedical Campus, UK.; NIHR BioResource, University of Cambridge, Cambridge Biomedical Campus, UK., Heemskerk JWM; Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, the Netherlands jwm.heemskerk@maastrichtuniversity.nl kd286@cam.ac.uk.

Publikováno v: Haematologica [Haematologica] 2019 Jun; Vol. 104 (6), pp. 1256-1267. Date of Electronic Publication: 2018 Dec 13.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

cAMP-PKA/EPAC signaling and cancer: the interplay in tumor microenvironment.

Autor: Zhang, Hongying¹ (AUTHOR), Liu, Yongliang¹ (AUTHOR), Liu, Jieya¹ (AUTHOR), Chen, Jinzhu¹ (AUTHOR), Wang, Jiao² (AUTHOR), Hua, Hui³ (AUTHOR) huahuihx@scu.edu.cn, Jiang, Yangfu¹ (AUTHOR) jyangfu@scu.edu.cn

Publikováno v: Journal of Hematology & Oncology. 1/17/2024, Vol. 17 Issue 1, p1-31. 31p.