Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Pilar Santisteban"'
Autor:
Franziska Haderk, Yu-Ting Chou, Lauren Cech, Celia Fernández-Méndez, Johnny Yu, Victor Olivas, Ismail M. Meraz, Dora Barbosa Rabago, D. Lucas Kerr, Carlos Gomez, David V. Allegakoen, Juan Guan, Khyati N. Shah, Kari A. Herrington, Oghenekevwe M. Gbenedio, Shigeki Nanjo, Mourad Majidi, Whitney Tamaki, Yashar K. Pourmoghadam, Julia K. Rotow, Caroline E. McCoach, Jonathan W. Riess, J. Silvio Gutkind, Tracy T. Tang, Leonard Post, Bo Huang, Pilar Santisteban, Hani Goodarzi, Sourav Bandyopadhyay, Calvin J. Kuo, Jeroen P. Roose, Wei Wu, Collin M. Blakely, Jack A. Roth, Trever G. Bivona
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Targeted therapy is effective in many tumor types including lung cancer, the leading cause of cancer mortality. Paradigm defining examples are targeted therapies directed against non-small cell lung cancer (NSCLC) subtypes with oncogenic alt
Externí odkaz:
https://doaj.org/article/be0a7eca3725431ab19bfe58739629b9
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Background Loss of the transcription factor GLI-Similar 3 (GLIS3) function causes congenital hypothyroidism (CH) in both humans and mice due to decreased expression of several thyroid hormone (TH) biosynthetic genes in thyroid follicular cel
Externí odkaz:
https://doaj.org/article/00d726bfdce14c65b8344d1a622b9f7c
Autor:
Julia Ramírez-Moya, León Wert-Lamas, Adrián Acuña-Ruíz, Alice Fletcher, Carlos Wert-Carvajal, Christopher J. McCabe, Pilar Santisteban, Garcilaso Riesco-Eizaguirre
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Thyroid cancer is the most common primary endocrine malignancy in adults and its incidence is rapidly increasing. Long non-coding RNAs (lncRNAs), generally defined as RNA molecules longer than 200 nucleotides with no protein-encoding capacit
Externí odkaz:
https://doaj.org/article/c28b93dd23654d67a6e525026b10e771
Autor:
Arístides López-Márquez, Carlos Carrasco-López, Andrea Martínez-Cano, Pascale Lemoine, Christophe E. Pierreux, Pilar Santisteban
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract While the signaling pathways and transcription factors involved in the differentiation of thyroid follicular cells, both in embryonic and adult life, are increasingly well understood, the underlying mechanisms and potential crosstalk between
Externí odkaz:
https://doaj.org/article/f6dbc66e26cc4015a2e84d20c6ec27d0
Autor:
Julia Ramírez-Moya, Christos Miliotis, Allison R. Baker, Richard I. Gregory, Frank J. Slack, Pilar Santisteban
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-20 (2021)
Abstract Background Adenosine deaminases acting on RNA (ADARs) modify many cellular RNAs by catalyzing the conversion of adenosine to inosine (A-to-I), and their deregulation is associated with several cancers. We recently showed that A-to-I editing
Externí odkaz:
https://doaj.org/article/3ca24ab8383d42e88c0f6bf7dd321fc5
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Thyroid differentiation of progenitor cells occurs during embryonic development and in the adult thyroid gland, and the molecular bases of these complex and finely regulated processes are becoming ever more clear. In this Review, we describe the most
Externí odkaz:
https://doaj.org/article/fa90d8beb31641368ccab382e677a75e
Autor:
Julia Ramírez-Moya, Pilar Santisteban
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
In the last two decades, great strides have been made in the study of microRNAs in development and in diseases such as cancer, as reflected in the exponential increase in the number of reviews on this topic including those on undifferentiated and wel
Externí odkaz:
https://doaj.org/article/b992bc07a68243989b5cb851ab86b4c2
Autor:
Iñigo Landa, Cesar Boullosa, Lucía Inglada-Pérez, Ana Sastre-Perona, Susana Pastor, Antonia Velázquez, Veronika Mancikova, Sergio Ruiz-Llorente, Francesca Schiavi, Ricard Marcos, Nuria Malats, Giuseppe Opocher, Ramon Diaz-Uriarte, Pilar Santisteban, Alfonso Valencia, Mercedes Robledo
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74765 (2013)
Papillary Thyroid Cancer (PTC) is a heterogeneous and complex disease; susceptibility to PTC is influenced by the joint effects of multiple common, low-penetrance genes, although relatively few have been identified to date. Here we applied a rigorous
Externí odkaz:
https://doaj.org/article/4c1f6195c3314c3c9d7f014736d1cc8e
Autor:
Lara P Fernández, Arístides López-Márquez, Angel M Martínez, Gonzalo Gómez-López, Pilar Santisteban
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62849 (2013)
BACKGROUND: FoxE1 is a thyroid-specific forkhead transcription factor essential for thyroid gland development, as well as for the maintenance of the thyroid differentiated state in adults. FoxE1 recognizes and binds to a short DNA sequence present in
Externí odkaz:
https://doaj.org/article/dbe73b10e9324dfa9d044eba4fa9ee45
Autor:
Iñigo Landa, Cesar Boullosa, Lucía Inglada-Pérez, Ana Sastre-Perona, Susana Pastor, Antonia Velázquez, Veronika Mancikova, Sergio Ruiz-Llorente, Francesca Schiavi, Ricard Marcos, Nuria Malats, Giuseppe Opocher, Ramon Diaz-Uriarte, Pilar Santisteban, Alfonso Valencia, Mercedes Robledo
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/a6a04b4068b148fa95548eb42e330427