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Akademický článek

Understanding plant to extract ratios in botanical extracts

Autor: Maria Monagas, Thomas Brendler, Josef Brinckmann, Steven Dentali, Stefan Gafner, Gabriel Giancaspro, Holly Johnson, James Kababick, Cuiying Ma, Hellen Oketch-Rabah, Pilar Pais, Nandu Sarma, Robin Marles

Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)

Dietary supplement current good manufacturing practice (cGMP) requires establishment of quality parameters for each component used in the manufacture of a dietary supplement to ensure that specifications for the identity, purity, strength, compositio

Externí odkaz: https://doaj.org/article/8a2b5f3b78244515986681f06a563586

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Determination of the potency of a novel saw palmetto supercritical CO2 extract (SPSE) for 5α-reductase isoform II inhibition using a cell-free in vitro test system

Autor: Dick Greenlaw, Pilar Pais, Santiago Rull, Agusti Villar

Publikováno v: Research and Reports in Urology

Pilar Pais, Agustí Villar, Santiago Rull Euromed, Barcelona, Spain Background: The nicotinamide adenine dinucleotide phosphate-dependent membrane protein 5α-reductase catalyses the conversion of testosterone to the most potent androgen – 5α-dihy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a240431f506644eb4106984dd7c4eb5e
http://europepmc.org/articles/PMC4847595

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Impact of a Proprietary Standardized Olive Fruit Extract (SOFE) on Cardio-Ankle Vascular Index, Visual Analog Scale and C-Reactive Protein Assessments in Subjects with Arterial Stiffness Risk

Autor: Agustin Villar, Pilar Pais, Santiago Rull

Publikováno v: Drugs in R&D

Introduction The chemical components of olive fruit provide a wide range of cardiovascular benefits. Arterial stiffness is an important cardiovascular risk factor and can be assessed using the Cardio-Ankle Vascular Index (CAVI). Objective The objecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635363fbd052ba0746e0505d117ff92a
https://pubmed.ncbi.nlm.nih.gov/27798770

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Chromatographic and related techniques for the determination of aromatic heterocyclic amines in foods

Autor: Mark G. Knize, Pilar Pais

Publikováno v: Journal of Chromatography B: Biomedical Sciences and Applications. 747:139-169

Some 20 years ago, Japanese scientists discovered a new group of highly toxic compounds, classified as heterocyclic aromatic amines, from broiled and grilled meat and fish products. Numerous studies have shown that most HAs are mutagenic and carcinog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a3f5aa6d1972b1f2835e69655e735a
https://doi.org/10.1016/s0378-4347(00)00118-3

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Formation of Mutagenic/Carcinogenic Heterocyclic Amines in Dry-Heated Model Systems, Meats, and Meat Drippings

Autor: James S. Felton, Pilar Pais, Mark G. Knize, Cynthia P. Salmon

Publikováno v: Journal of Agricultural and Food Chemistry. 47:1098-1108

Mixtures of amino acids, creatine, and glucose simulating the composition of six different kinds of meats (beef, chicken breast, chicken thigh, turkey breast, pork, and fish) were dry-heated to simulate the formation of heterocyclic amines in meats.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0748cc67185a96632a588ab16e98aaf
https://doi.org/10.1021/jf980644e

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Chemical analysis and significance of heterocyclic aromatic amines

Autor: James S. Felton, Cynthia P. Salmon, Pilar Pais, Mark G. Knize

Publikováno v: Zeitschrift f�r Lebensmitteluntersuchung und -Forschung A. 207:434-440

Levels of known heterocyclic amines vary from undetectable in many meats sold in fast food restaurants, to over 10 ng/g for meats prepared in restaurants that cook food to order, to hundreds of nanograms per gram for some meats cooked under certain h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6089a3ec81b6f30aa3da82b95d2fd04b
https://doi.org/10.1007/s002170050357

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Potency of a novel saw palmetto ethanol extract, SPET-085, for inhibition of 5alpha-reductase II

Autor: Pilar Pais

Publikováno v: Advances in therapy. 27(8)

The nicotinamide adenine dinucleotide phosphate (NADPH)-dependent membrane protein 5alpha-reductase irreversibly catalyses the conversion of testosterone to the most potent androgen, 5alpha-dihydrotestosterone (DHT). In humans, two 5alpha-reductase i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecf5897ebf5c5a9850c3de2e1101cab7
https://pubmed.ncbi.nlm.nih.gov/20623347

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Food Heating and the Formation of Heterocyclic Aromatic Amine and Polycyclic Aromatic Hydrocarbon Mutagens/Carcinogens

Autor: Cynthia P. Salmon, James S. Felton, Mark G. Knize, Pilar Pais

Publikováno v: Advances in Experimental Medicine and Biology ISBN: 9781461372011

Heterocyclic aromatic amines (HAA) and polycyclic aromatic hydrocarbons (PAH) are mutagens and animal carcinogens sometimes formed when foods are heated or processed. Determining their role in cancer etiology depends on comparing human exposures and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0b184b1d250f9e79f042c2754f2073dd
https://doi.org/10.1007/978-1-4615-4853-9_12

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Periodical

Euromed USA, Inc.

Publikováno v: Nutraceuticals World. Company Capabilities 2017, Vol. 20 Issue Part 2, p32-32. 1p.

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