Zobrazeno 1 - 10 of 39 pro vyhledávání: '"Pilar López‐Nieva"'
1
Akademický článek
Differential molecular response in mice and human thymocytes exposed to a combined-dose radiation regime
Autor: Pilar López-Nieva, Iria González-Vasconcellos, Laura González-Sánchez, María A. Cobos-Fernández, Sara Ruiz-García, Raúl Sánchez Pérez, Ángel Aroca, José Fernández-Piqueras, Javier Santos
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract In the quest for more effective radiation treatment options that can improve both cell killing and healthy tissue recovery, combined radiation therapies are lately in the spotlight. The molecular response to a combined radiation regime where
Externí odkaz: https://doaj.org/article/f67abbf5a64040c4a4c1b91f3827cade
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2
Akademický článek
Identification of NRF2 Activation as a Prognostic Biomarker in T-Cell Acute Lymphoblastic Leukaemia
Autor: María Villa-Morales, Laura Pérez-Gómez, Eduardo Pérez-Gómez, Pilar López-Nieva, Pablo Fernández-Navarro, Javier Santos
Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 12, p 10350 (2023)
The standard-of-care treatment of T-cell acute lymphoblastic leukaemia (T-ALL) with chemotherapy usually achieves reasonable rates of initial complete response. However, patients who relapse or do not respond to conventional therapy show dismal outco
Externí odkaz: https://doaj.org/article/e568ebac34244decb41903ee781a04ed
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3
Akademický článek
The use of PanDrugs to prioritize anticancer drug treatments in a case of T-ALL based on individual genomic data
Autor: Pablo Fernández-Navarro, Pilar López-Nieva, Elena Piñeiro-Yañez, Gonzalo Carreño-Tarragona, Joaquín Martinez-López, Raúl Sánchez Pérez, Ángel Aroca, Fátima Al-Shahrour, María Ángeles Cobos-Fernández, José Fernández-Piqueras
Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Acute T-cell lymphoblastic leukaemia (T-ALL) is an aggressive disorder derived from immature thymocytes. The variability observed in clinical responses on this type of tumours to treatments, the high toxicity of current protocols
Externí odkaz: https://doaj.org/article/4844963c8bf847eb979d9da891212543
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4
Akademický článek
Patterns of Differentially Expressed circRNAs in Human Thymocytes
Autor: Pilar López-Nieva, Pablo Fernández-Navarro, María Ángeles Cobos-Fernández, Iria González-Vasconcellos, Raúl Sánchez Pérez, Ángel Aroca, José Fernández-Piqueras, Javier Santos
Publikováno v: Non-Coding RNA, Vol 8, Iss 2, p 26 (2022)
Circular RNAs (circRNAs) are suggested to play a discriminative role between some stages of thymocyte differentiation. However, differential aspects of the stage of mature single-positive thymocytes remain to be explored. The purpose of this study is
Externí odkaz: https://doaj.org/article/e4089ec3c5174c6b996216c1abd000af
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5
Akademický článek
RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas
Autor: Pilar López-Nieva, Pablo Fernández-Navarro, Concepción Vaquero-Lorenzo, María Villa-Morales, Osvaldo Graña-Castro, María Ángeles Cobos-Fernández, José Luis López-Lorenzo, Pilar Llamas, Laura González-Sanchez, Isabel Sastre, Marina Pollan, Marcos Malumbres, Javier Santos, José Fernández-Piqueras
Publikováno v: BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Precursor T-cell lymphoblastic lymphomas (T-LBL) are rare aggressive hematological malignancies that mainly develop in children. As in other cancers, the loss of cell cycle control plays a prominent role in the pathogenesis in the
Externí odkaz: https://doaj.org/article/8c05930c4cca48cc98e127c09078321c
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7
Identification of NRF2 Activation as a Prognostic Biomarker in T-Cell Acute Lymphoblastic Leukaemia
Autor: Santos, María Villa-Morales, Laura Pérez-Gómez, Eduardo Pérez-Gómez, Pilar López-Nieva, Pablo Fernández-Navarro, Javier
Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 10350
The standard-of-care treatment of T-cell acute lymphoblastic leukaemia (T-ALL) with chemotherapy usually achieves reasonable rates of initial complete response. However, patients who relapse or do not respond to conventional therapy show dismal outco
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=multidiscipl::0e04ae550a5f806850fc930191639a10
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