Development and validation of a prognostic model to predict birth weight: individual participant data meta-analysis

Autor: François Goffinet, Paul T Seed, Jørn Olsen, Renato T Souza, Louise C Kenny, José Guilherme Cecatti, Ben W Mol, Jane E Norman, Jun Zhang, Ana Pilar Betran, Kym I E Snell, Richard D Riley, Seppo Heinonen, Anne Eskild, Fionnuala M McAuliffe, Mark Brown, Henk Groen, Alice Rumbold, Kerstin Klipstein-Grobusch, Line Sletner, Anne Karen Jenum, Fionnuala Mone, Hema Mistry, Eric A P Steegers, Shigeru Saito, Arri Coomarasamy, Fabio Facchinetti, Lucilla Poston, Shakila Thangaratinam, SeonAe Yeo, Joyce L Browne, Eva Pajkrt, Wessel Ganzevoort, Kjell Salvesen, Helena Teede, Lucy Chappell, Maria Makrides, Guillermo Carroli, Javier Zamora, Pisake Lumbiganon, Asma Khalil, John Kingdom, Gustaaf Dekker, Robert Gibson, Lionel Carbillon, John Allotey, Dyuti Coomar, Jane West, Marleen Temmerman, Satoru Takeda, Federico Prefumo, Hannele Laivuori, Sohinee Bhattacharya, Sander M J van Kuijk, Lucinda Archer, Jenny Myers, Lisa M Askie, Sergio Ferrazzani, Melanie Smuk, Caroline A Crowther, Francesc Figueras, Lill Trogstad, Maureen Macleod, Claire T Roberts, François Audibert, Ary I Savitri, Lesley McCowan, Wendy S Meschino, Diane Farrar, Yves Giguère, Tianhua Huang, Hans Wolf, Tiziana Frusca, Silvia Salvi, Patrizia Vergani, Chie Nagata, George Daskalakis, Olav Lapaire, Enrico Ferrazzi, Baskaran Thilaganathan, Christopher Redman, Agustin Conde-Agudelo, Nelly Zavaleta, Josje Langenveld, Karlijn C Vollebregt, Jacques Massé, Francesca Crovetto, Mariana Widmer, Ignacio Herraiz, Alberto Galindo, Jean-Claude Forest, Stefan Verlohren, Luc Smits, Edouard Lecarpentier, Per Minor Magnus, Linda Gough, Alex Kwong, Akihide Ohkuchi, Fabricio Da Silva Costa, Athena P Souka, Rinat Gabbay-Benziv, Evan Sequeira, Rachel Katherine Morris, Ahmet A Baschat, Dewi Anggraini, Marleen van Gelder, Sadia Haqnawaz, Cuno SPM Uiterwaal, Annetine C Staff, Louise Bjoerkholt Andersen, Elisa Llurba Olive, Javier Arenas Ramírez, Peter A Zimmerman, Catherine Riddell, Joris van de Post, Sebastián E Illanes, Claudia Holzman, Pia M Villa, Luxmi Velauthar, Miriam van Oostwaard, Christina A Vinter, Camilla Haavaldsen, Inge Eisensee, Ernesto A Figueiró-Filho, Jacob A Lykke, Alfred Mbah, Gordon G S Smith, Read Salim, Annemarijne Adank, Rebecca E Allen, Jan Stener Jørgensen, Anthony O Odibo, Bassam G Haddad, Emily C Kleinrouweler, Ragnhild Bergene Skråstad, Kajantie Eero, Athanasios Pilalis, Lee Ann Hawkins

Publikováno v: BMJ Medicine, Vol 3, Iss 1 (2024)

Objective To predict birth weight at various potential gestational ages of delivery based on data routinely available at the first antenatal visit.Design Individual participant data meta-analysis.Data sources Individual participant data of four cohor

Externí odkaz: https://doaj.org/article/1abaafceeca044b6916e9151f830bd27

Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer

Autor: Aitor Almanza, Katarzyna Mnich, Arnaud Blomme, Claire M. Robinson, Giovanny Rodriguez-Blanco, Sylwia Kierszniowska, Eoghan P. McGrath, Matthieu Le Gallo, Eleftherios Pilalis, Johannes V. Swinnen, Aristotelis Chatziioannou, Eric Chevet, Adrienne M. Gorman, Afshin Samali

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)

IRE1α cleaves several mRNAs upon accumulation of misfolded proteins. Here the authors show that active IRE1α cleaves DGAT2 mRNA encoding the rate-limiting enzyme in the synthesis of triacylglycerols, suggesting a role of IRE1α in reprogramming lip

Externí odkaz: https://doaj.org/article/5880a9d0a80d435dbe79e1dfb4bc9b6f

Decitabine potentiates efficacy of doxorubicin in a preclinical trastuzumab-resistant HER2-positive breast cancer models

Autor: Verona Buocikova, Eleonora Marta Longhin, Eleftherios Pilalis, Chara Mastrokalou, Svetlana Miklikova, Marina Cihova, Alexandra Poturnayova, Katarina Mackova, Andrea Babelova, Lenka Trnkova, Naouale El Yamani, Congying Zheng, Ivan Rios-Mondragon, Martina Labudova, Lucia Csaderova, Kristina Mikus Kuracinova, Peter Makovicky, Lucia Kucerova, Miroslava Matuskova, Mihaela Roxana Cimpan, Maria Dusinska, Pavel Babal, Aristotelis Chatziioannou, Alena Gabelova, Elise Rundén-Pran, Bozena Smolkova

Publikováno v: Biomedicine & Pharmacotherapy, Vol 147, Iss , Pp 112662- (2022)

Acquired drug resistance and metastasis in breast cancer (BC) are coupled with epigenetic deregulation of gene expression. Epigenetic drugs, aiming to reverse these aberrant transcriptional patterns and sensitize cancer cells to other therapies, prov

Externí odkaz: https://doaj.org/article/1345e26c32b84eee948affb57a4afc4c

ERβ1 Sensitizes and ERβ2 Desensitizes ERα-Positive Breast Cancer Cells to the Inhibitory Effects of Tamoxifen, Fulvestrant and Their Combination with All-Trans Retinoic Acid

Autor: Aggeliki K. Meligova, Dimitra Siakouli, Sotiria Stasinopoulou, Despoina S. Xenopoulou, Maria Zoumpouli, Vassiliki Ganou, Eleni-Fani Gkotsi, Aristotelis Chatziioannou, Olga Papadodima, Eleftherios Pilalis, Michael N. Alexis, Dimitra J. Mitsiou

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 4, p 3747 (2023)

Adjuvant endocrine therapy (AET) is the treatment of choice for early-stage estrogen receptor alpha (ERα)-positive breast cancer (BC). However, almost 40% of tamoxifen-treated cases display no response or a partial response to AET, thus increasing t

Externí odkaz: https://doaj.org/article/f8b6164dfed14d41bedc2b1c88b2aaeb

Comparative Evaluation of Reproducibility of Phage-Displayed Peptide Selections and NGS Data, through High-Fidelity Mapping of Massive Peptide Repertoires.

Autor: Petry, Klaus G.^1,2 (AUTHOR) klaus.petry@inserm.fr, Pilalis, Eleftherios^3,4 (AUTHOR), Chatziioannou, Aristotelis^3,4 (AUTHOR) klaus.petry@inserm.fr

Publikováno v: International Journal of Molecular Sciences. Jan2023, Vol. 24 Issue 2, p1594. 13p.