Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Pil-Su Ho"'
Publikováno v:
Journal of pharmacological and toxicological methods. 119
Histamine is strongly associated with the onset of allergic conjunctivitis. The most recent cloned histamine H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ae44ba377fd52261ed6b262d9dcf4a77
https://pubmed.ncbi.nlm.nih.gov/35842185
https://pubmed.ncbi.nlm.nih.gov/35842185
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 119:107203
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::163d0a63ad1bc8ced6701be2b630ebe2
https://doi.org/10.1016/j.vascn.2022.107203
https://doi.org/10.1016/j.vascn.2022.107203
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 113:107133
Allergic conjunctivitis is one of the most common immune diseases in the field of ophthalmology. The number of patients suffering from allergic conjunctivitis has been increasing, and there is still a strong need for development of therapeutic agents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1681edbd25b7a4b22f2f57f2207b3fcd
https://doi.org/10.1016/j.vascn.2021.107133
https://doi.org/10.1016/j.vascn.2021.107133
Autor:
Kwangseok Ko, Chan Hee Park, Seung-Su Oh, Young Jin Kwon, Jung-Sook Kim, Eun-Jung Park, Woul-Seong Park, Soon Ok Lee, D.H. Yoon, Woon-Ki Cho, Yu-Mi Song, Kyoung-June Lee, Cho-Rong Min, Jieun Lee, Kazumi Morikawa, Ju-Han Yoon, Pil-Su Ho, Hye Jung Kim, Jee-Hun Yun, Yu Chul Kim
Publikováno v:
Journal of Medicinal Chemistry. 61:2949-2961
The histamine H4 receptor (H4R), a member of the G-protein coupled receptor family, has been considered as a potential therapeutic target for treating atopic dermatitis (AD). A large number of H4R antagonists have been disclosed, but no efficient age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d88d12c5eea8aadf1f6fc21b2441244
https://doi.org/10.1021/acs.jmedchem.7b01855
https://doi.org/10.1021/acs.jmedchem.7b01855
Autor:
Naoki Harada, Kiyoshi Yoshinari, Kenji Takanashi, Noriyuki Furuichi, Ikumi Hyohdoh, Kazutomo Ori, Mitsuyasu Tabo, Fumio Watanabe, Haruyoshi Shirai, Yasushi Tomii, Nobuo Shimma, Pil-Su Ho, Toshihiro Aoki, Hitoshi Iikura, Sawako Ozawa, Masahiro Sakaitani, Yuko Aoki, Yoshiko Itezono, Masayuki Matsushita
Publikováno v:
ACS Medicinal Chemistry Letters. 4:1059-1063
A facile methodology effective in obtaining a set of compounds monofluorinated at various positions (fluorine scan) by chemical synthesis is reported. Direct and nonselective fluorination reactions of our lead compound 1a and key intermediate 2a work
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd743460b41c992b38ef8f3fe1eef0ac
https://doi.org/10.1021/ml4002419
https://doi.org/10.1021/ml4002419
Publikováno v:
Synthetic Communications. 28:1481-1489
The cross-coupling reaction of organoboronic acids and carbon monoxide (1 atm) with aryl-, alkenyl-, and alkynyliodonium salts at room temperature afforded unsymmetric aromatic ketones in moderate yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf358793a13f38f5671d5e3578e22f86
https://doi.org/10.1080/00397919808006847
https://doi.org/10.1080/00397919808006847
Publikováno v:
Tetrahedron Letters. 38:1947-1950
Arylation and alkenylation of 1-ethoxy-1-trimetylsilyloxycyclopropane with diphenyliodonium tetrafluoroborate and alkenyliodonium tetrafluoroborate were accomplished by slow addition of silyloxycyclopropane to iodonium salts in the presence of Pd(OAc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::848fe1df683e4c4e0eebdea15181e446
https://doi.org/10.1016/s0040-4039(97)00230-x
https://doi.org/10.1016/s0040-4039(97)00230-x
Publikováno v:
Synthetic Communications. 26:3225-3235
Allylic substitution of allylic cyclic carbonates with PhSH or PhOH in the presence of CpRu(PPh3)2Cl (5 mol %) afforded (E)-allylic alcohol and erythro-β-hydroxy thiophenoxide or phenoxide respectively, via external attack of nucleophiles to π-ally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24340190e779c9d4eeefd536b55b6257
https://doi.org/10.1080/00397919608004631
https://doi.org/10.1080/00397919608004631
Publikováno v:
Synthetic Communications. 26:1493-1498
Allylation of aldehydes by reaction allylic phosphates with diethylzinc in the presence of Pd(PPh3)4 afforded homoallylic alcohol via nucleophilic allylzinc species.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eda9a7599e90734bbdab2d17fc8fdab0
https://doi.org/10.1080/00397919608003515
https://doi.org/10.1080/00397919608003515
Publikováno v:
Synthetic Communications. 26:1485-1492
RuH2(PPh3)4-catalyzed reductive cleavage reactions of chiral allylic cyclic carbonates with ammonium formate afforded optically active (E)-allylic alcohols with excellent regioselectivity. Alternatively, hydrogenolysis of propargylic cyclic carbonate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af9b954dd293916c90c5d07e31252505
https://doi.org/10.1080/00397919608003514
https://doi.org/10.1080/00397919608003514