Follicle-stimulating hormone (FSH) activates extracellular signal-regulated kinase phosphorylation independently of beta-arrestin- and dynamin-mediated FSH receptor internalization

Autor: Crepieux Pascale, Reiter Eric, Guillou Florian, Kara Elodie, Piketty Vincent

Publikováno v: Reproductive Biology and Endocrinology, Vol 4, Iss 1, p 33 (2006)

Abstract Background The follicle-stimulating hormone receptor (FSH-R) is a seven transmembrane spanning receptor (7TMR) which plays a crucial role in male and female reproduction. Upon FSH stimulation, the FSH-R activates the extracellular signal-reg

Externí odkaz: https://doaj.org/article/1dd13fb44d1b44b49fff00edf08d6f5b

S680 single nucleotide polymorphism of the FSH receptor increases FSH-induced beta-arrestin recruitment while reducing beta-arrestin-dependent translocation of active PKA to the nucleus

Autor: Tranchant, Thibaud, Durand, Guillaume, Landomiel, Flavie, Jegot, Gwenhael, Gallay, Nathalie, Piketty, Vincent, Gauthier, Christophe, Ulloa-Aguirre, Alfredo, Bourquard, Thomas, Poupon, Anne, Crepieux, Pascale, Royère, Dominique, Reiter, Eric

Publikováno v: Gordon Research Conference in Molecular Pharmacology
Gordon Research Conference in Molecular Pharmacology, Apr 2013, Lucca (Barga), Italy. 2013

International audience; A polymorphism at position 680 (N→S) of the human FSH receptor (FSHR) has been associated with an increased resistance to FSH in women bearing an S/S genotype, whereas the effects of ovarian hyperstimulation syndrome (OHSS)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ca8f2744413225ce6700138460076df7
https://hal.inrae.fr/hal-02811177

The N680S single nucleotide polymorphism (SNP) of the human FSH receptor (hFSHR) impacts on PKA nuclear translocation and CREB-dependent gene transcription

Autor: Tranchant, Thibaud, Durand, Guillaume, Piketty, Vincent, Gauthier, Christophe, Crépieux, Pascale, Royère, Dominique, Reiter, Eric

Publikováno v: 36. European Symposium on Hormones and Cell Regulation GPCRs: Pharmacology, Physiology and Pathology
36. European Symposium on Hormones and Cell Regulation GPCRs: Pharmacology, Physiology and Pathology, European Society of Endocrinology (ESE). Labo/service de l'auteur, Bristol, GBR., Oct 2011, Mont Sainte Odile, France. 2 p

National audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::dff33695ec5a7ad96cd6b1e06cf9c96f
https://hal.inrae.fr/hal-02803747

Modelling of FSHR-induced signalling network

Autor: Heitzler, Domitille, Durand, Guillaume, Dupuy, Laurence, Gauthier, Christophe, Piketty, Vincent, Crepieux, Pascale, Rizk, Aurélien, Soliman, Sylvain, Fages, Francois, Clement, Frédéric, Reiter, Eric

Publikováno v: International Conference for Gonadotropins & their Receptors
International Conference for Gonadotropins & their Receptors, Jul 2008, Hertfordshire, United Kingdom. n.p

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::033a0f37989839569bbcfb62f181beff
https://hal.inrae.fr/hal-02822871

G protein-coupled receptor kinase 2 and beta-arrestins are recruited to FSH receptor in stimulated rat primary Sertoli cells

Autor: Marion, Sébastien, Kara, Elodie, Crépieux, Pascale, Piketty, Vincent, Martinat, Nadine, Guillou, Florian Jean Louis, Reiter, Eric

Publikováno v: Journal of Endocrinology
Journal of Endocrinology, BioScientifica, 2006, 190 (2), pp.341-350

International audience

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1ef099cf5ac5305861526d3e006bdc4c
https://hal.inrae.fr/hal-02660876