Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Pike KG"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Pike KG; Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Hunt TA; Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Barlaam B; Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Benstead D; Pharmaceutical Sciences, AstraZeneca, Silk Road Business Park, Macclesfield SK10 2NA, U.K., Cadogan E; Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Chen K; Innovation Center China, Asia & Emerging Markets iMED, 199 Liangjing Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China., Cook CR; Pharmaceutical Sciences, AstraZeneca, Silk Road Business Park, Macclesfield SK10 2NA, U.K., Colclough N; Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Deng C; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing 100176, P. R. China., Durant ST; Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Eatherton A; Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Goldberg K; Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Johnström P; PET Science Centre, Precision Medicine and Biosamples, Oncology R&D, AstraZeneca, Karolinska Institutet, Stockholm SE-171 76, Sweden.; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm SE-171 76, Sweden., Liu L; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing 100176, P. R. China., Liu Z; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing 100176, P. R. China., Nissink JWM; Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Pang C; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing 100176, P. R. China., Pass M; Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Robb GR; Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Roberts C; Discovery Sciences, AstraZeneca, Cambridge CB2 0AA, U.K., Schou M; PET Science Centre, Precision Medicine and Biosamples, Oncology R&D, AstraZeneca, Karolinska Institutet, Stockholm SE-171 76, Sweden.; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm SE-171 76, Sweden., Steward O; Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Sykes A; Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Yan Y; Innovation Center China, Asia & Emerging Markets iMED, 199 Liangjing Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China., Zhai B; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing 100176, P. R. China., Zheng L; Innovation Center China, Asia & Emerging Markets iMED, 199 Liangjing Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2024 Feb 22; Vol. 67 (4), pp. 3090-3111. Date of Electronic Publication: 2024 Feb 02.
Autor:
Andrews DM; Medicinal Chemistry, Oncology R&D, Research and Early Development, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, UK., Cartic S; Cancer Research UK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK., Cosulich S; Medicinal Chemistry, Oncology R&D, Research and Early Development, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, UK., Divecha N; Inositide Laboratory, School of Biological Sciences, Faculty of Environmental and Life Sciences, Life Sciences Building 85, University of Southampton, Highfield Campus, Southampton, SO17 1BJ, UK., Faulder P; Medicinal Chemistry, Oncology R&D, Research and Early Development, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, UK., Flemington V; Medicinal Chemistry, Oncology R&D, Research and Early Development, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, UK., Kern O; Cancer Research UK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK., Kettle JG; Medicinal Chemistry, Oncology R&D, Research and Early Development, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, UK., MacDonald E; Cancer Research UK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK., McKelvie J; Cancer Research UK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK., Pike KG; Medicinal Chemistry, Oncology R&D, Research and Early Development, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, UK., Roberts B; Medicinal Chemistry, Oncology R&D, Research and Early Development, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, UK., Rowlinson R; Medicinal Chemistry, Oncology R&D, Research and Early Development, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, UK., Smith JM; Medicinal Chemistry, Oncology R&D, Research and Early Development, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, UK. Electronic address: james.smith3@astrazeneca.com., Stockley M; Cancer Research UK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK., Swarbrick ME; Cancer Research UK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK., Treinies I; Cancer Research UK Therapeutic Discovery Laboratories, Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK., Waring MJ; Medicinal Chemistry, Oncology R&D, Research and Early Development, AstraZeneca, Cambridge Science Park, Unit 310 Darwin Building, Cambridge CB4 0WG, UK.
Publikováno v:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2022 Jan 15; Vol. 54, pp. 116557. Date of Electronic Publication: 2021 Dec 12.
Autor:
Bagal SK; AstraZeneca, 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0AA, United Kingdom., Gregson C; AstraZeneca, 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0AA, United Kingdom., O' Donovan DH; AstraZeneca, 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0AA, United Kingdom., Pike KG; AstraZeneca, 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0AA, United Kingdom., Bloecher A; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Barton P; AstraZeneca, 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0AA, United Kingdom., Borodovsky A; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Code E; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Fillery SM; AstraZeneca, 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0AA, United Kingdom., Hsu JH; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Kawatkar SP; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Li C; Pharmaron Beijing Co., Ltd., 6 Taihe Road, BDA, Beijing 100176, P. R. China., Longmire D; AstraZeneca, 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0AA, United Kingdom., Nai Y; Pharmaron Beijing Co., Ltd., 6 Taihe Road, BDA, Beijing 100176, P. R. China., Nash SC; AstraZeneca, 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0AA, United Kingdom., Pike A; AstraZeneca, 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0AA, United Kingdom., Robinson J; AstraZeneca, 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0AA, United Kingdom., Read JA; AstraZeneca, 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0AA, United Kingdom., Rawlins PB; AstraZeneca, 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0AA, United Kingdom., Shen M; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Tang J; Pharmaron Beijing Co., Ltd., 6 Taihe Road, BDA, Beijing 100176, P. R. China., Wang P; Pharmaron Beijing Co., Ltd., 6 Taihe Road, BDA, Beijing 100176, P. R. China., Woods H; AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States., Williamson B; AstraZeneca, 1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0AA, United Kingdom.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2021 Dec 09; Vol. 64 (23), pp. 17146-17183. Date of Electronic Publication: 2021 Nov 22.
Autor:
Barlaam B; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., De Savi C; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Dishington A; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Drew L; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Ferguson AD; Discovery Sciences, AstraZeneca, Boston, Massachusetts 02451, United States., Ferguson D; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Gu C; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Hande S; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Hassall L; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Hawkins J; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Hird AW; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Holmes J; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Lamb ML; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Lister AS; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., McGuire TM; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Moore JE; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., O'Connell N; Discovery Sciences, AstraZeneca, Boston, Massachusetts 02451, United States., Patel A; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Pike KG; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Sarkar U; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Shao W; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Stead D; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Varnes JG; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Vasbinder MM; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Wang L; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing 100176, P. R. China., Wu L; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing 100176, P. R. China., Xue L; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing 100176, P. R. China., Yang B; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Yao T; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing 100176, P. R. China.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2021 Oct 28; Vol. 64 (20), pp. 15189-15213. Date of Electronic Publication: 2021 Oct 14.
Autor:
O' Donovan DH; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom. Electronic address: daniel.odonovan@astrazeneca.com., Gregson C; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Packer MJ; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Greenwood R; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Pike KG; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Kawatkar S; Oncology R&D, AstraZeneca, 35 Gatehouse Drive, Waltham, MA 02451, United States., Bloecher A; Oncology R&D, AstraZeneca, 35 Gatehouse Drive, Waltham, MA 02451, United States., Robinson J; Discovery Sciences R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Read J; Discovery Sciences R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Code E; Discovery Sciences R&D, 35 Gatehouse Drive, Waltham, MA 02451, United States., Hsu JH; Oncology R&D, AstraZeneca, 35 Gatehouse Drive, Waltham, MA 02451, United States., Shen M; Oncology R&D, AstraZeneca, 35 Gatehouse Drive, Waltham, MA 02451, United States., Woods H; Oncology R&D, AstraZeneca, 35 Gatehouse Drive, Waltham, MA 02451, United States., Barton P; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Fillery S; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Williamson B; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Rawlins PB; Discovery Sciences R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom., Bagal SK; Oncology R&D, AstraZeneca, Cambridge CB4 0WG, United Kingdom.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 May 01; Vol. 39, pp. 127904. Date of Electronic Publication: 2021 Mar 06.
Autor:
Barlaam B; Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Casella R; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Cidado J; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Cook C; Oncology R&D, AstraZeneca, Macclesfield, SK10 2NA, United Kingdom., De Savi C; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Dishington A; Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Donald CS; Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Drew L; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Ferguson AD; Discovery Sciences, AstraZeneca, Boston, Massachusetts 02451, United States., Ferguson D; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Glossop S; Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Grebe T; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Gu C; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Hande S; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Hawkins J; Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Hird AW; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Holmes J; Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Horstick J; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Jiang Y; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing, 100176, P. R. China., Lamb ML; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., McGuire TM; Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Moore JE; Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., O'Connell N; Discovery Sciences, AstraZeneca, Boston, Massachusetts 02451, United States., Pike A; Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Pike KG; Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Proia T; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Roberts B; Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., San Martin M; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Sarkar U; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Shao W; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Stead D; Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Sumner N; Oncology R&D, AstraZeneca, Cambridge, CB4 0WG, United Kingdom., Thakur K; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Vasbinder MM; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Varnes JG; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Wang J; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Wang L; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing, 100176, P. R. China., Wu D; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Wu L; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing, 100176, P. R. China., Yang B; Oncology R&D, AstraZeneca, Boston, Massachusetts 02451, United States., Yao T; Pharmaron Beijing Co., Ltd., 6 Taihe Road BDA, Beijing, 100176, P. R. China.
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 2020 Dec 24; Vol. 63 (24), pp. 15564-15590. Date of Electronic Publication: 2020 Dec 11.