A role for the cystathionine-β-synthase /H2S axis in astrocyte dysfunction in the aging brain

Autor: Anindya Dey, Pijush Kanti Pramanik, Shailendra Kumar Dhar Dwivedi, Fiifi Neizer-Ashun, Tamas Kiss, Abhrajit Ganguly, Heather Rice, Priyabrata Mukherjee, Chao Xu, Mohiuddin Ahmad, Anna Csiszar, Resham Bhattacharya

Publikováno v: Redox Biology, Vol 68, Iss , Pp 102958- (2023)

Astrocytic dysfunction is central to age-related neurodegenerative diseases. However, the mechanisms leading to astrocytic dysfunction are not well understood. We identify that among the diverse cellular constituents of the brain, murine and human as

Externí odkaz: https://doaj.org/article/67c748f9ff7546d08f2ad8602b705bee

Serine protease inhibitors rich Coccinia grandis (L.) Voigt leaf extract induces protective immune responses in murine visceral leishmaniasis

Autor: Asmita Pramanik, Dibyendu Paik, Pijush Kanti Pramanik, Tapati Chakraborti

Publikováno v: Biomedicine & Pharmacotherapy, Vol 111, Iss , Pp 224-235 (2019)

Leishmaniasis is a parasite-mediated tropical disease affecting millions of individuals worldwide. The available antileishmanial chemotherapeutic modalities exhibit adverse toxicity, exorbitant price and advent of drug-resistant parasites. Hence, pla

Externí odkaz: https://doaj.org/article/c5f905fc09c04751b12d9a2aa6ffe940

PKCζ–NADPH Oxidase–PKCα Dependent Kv1.5 Phosphorylation by Endothelin-1 Modulates Nav1.5–NCX1–Cav1.2 Axis in Stimulating Ca2+ Level in Caveolae of Pulmonary Artery Smooth Muscle Cells

Autor: Jaganmay Sarkar, Sajal Chakraborti, Tapati Chakraborti, Amritlal Mandal, Pijush Kanti Pramanik, Priyanka Ghosh

Publikováno v: Cell Biochemistry and Biophysics. 79:57-71

Endothelin-1 (ET-1) is a potent endogenously derived vasoconstrictor, which increases pulmonary hypertension via stimulation of [Ca2+]i level in pulmonary artery smooth muscle cells (PASMCs). In this communication, we sought to investigate the mechan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2511c5a1072c9d3fbac8a941bc1d6a2b
https://doi.org/10.1007/s12013-020-00954-x

Some Aspects of Oxidative Stress–Induced Prostate Cancer Therapy

Autor: Md Nur Alam, Tapati Chakraborti, Priyanka Ghosh, Pijush Kanti Pramanik, Pujayita Devgupta, Sajal Chakraborti

Publikováno v: Handbook of Oxidative Stress in Cancer: Therapeutic Aspects ISBN: 9789811612473
Handbook of Oxidative Stress in Cancer: Therapeutic Aspects ISBN: 9789811654213

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c73ad287e65bcee13f81f151915f19
https://doi.org/10.1007/978-981-16-1247-3_144-1

Bioassay-based Corchorus capsularis L. leaf-derived β-sitosterol exerts antileishmanial effects against Leishmania donovani by targeting trypanothione reductase

Autor: Angshuman Bagchi, Sajal Chakraborti, Pijush Kanti Pramanik, Tapati Chakraborti

Publikováno v: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)

Leishmaniasis, a major neglected tropical disease, affects millions of individuals worldwide. Among the various clinical forms, visceral leishmaniasis (VL) is the deadliest. Current antileishmanial drugs exhibit toxicity- and resistance-related issue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5da7085939d87e644adcce44d19a862
http://europepmc.org/articles/PMC7686382