Genetic Markers of Toxicity From Capecitabine and Other Fluorouracil-Based Regimens: Investigation in the QUASAR2 Study, Systematic Review, and Meta-Analysis

Autor: Rosmarin, D, Palles, C, Church, D, Domingo, E, Jones, A, Johnstone, E, Wang, H, Love, S, Julier, P, Scudder, C, Nicholson, G, Gonzalez-Neira, A, Martin, M, Sargent, D, Green, E, McLeod, H, Zanger, UM, Schwab, M, Braun, M, Seymour, M, Thompson, L, Lacas, B, Boige, V, Ribelles, N, Afzal, S, Enghusen, H, Jensen, SA, Etienne-Grimaldi, MC, Milano, G, Wadelius, M, Glimelius, B, Garmo, H, Gusella, M, Lecomte, T, Laurent-Puig, P, Martinez-Balibrea, E, Sharma, R, Garcia-Foncillas, J, Kleibl, Z, Morel, A, Pignon, JP, Midgley, R, Kerr, D, Tomlinson, I

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, 32 (10), pp.1031-1039. ⟨10.1200/JCO.2013.51.1857⟩

International audience; Purpose Fluourouracil (FU) is a mainstay of chemotherapy, although toxicities are common. Genetic biomarkers have been used to predict these adverse events, but their utility is uncertain.Patients and Methods We tested candida

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c0d4f4e50a6114bf5db0a60e7af384a6
https://europepmc.org/articles/PMC4879695/

[Complete (R0) resection is the only valid prognostic factor in abdominoperineal resection for recurrent cancer of the anal canal (a consecutive series of 95 patients)]

Autor: Rouquie, D, Lasser, P, Castaing, MARINE VERONIQUE, Boige, V, Goéré, D, Pignon, Jp, Ducreux, M, Elias, D, Pocard, M.

Publikováno v: Journal de chirurgie. 145(4)

When radiation therapy fails to control cancer of the anal canal, the only therapeutic alternative is salvage abdomino-perineal resection (APR). Its role remains debatable since very few long-term survivals have been reported. No prognostic factors h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::cb5777ee46be1c68ba2b3f1a5dd81fad
https://pubmed.ncbi.nlm.nih.gov/18955923

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