Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Pietro P. Sanna"'
Autor:
András H. Lékó, Adriana Gregory-Flores, Renata C. N. Marchette, Juan L. Gomez, Janaina C. M. Vendruscolo, Vez Repunte-Canonigo, Vicky Choung, Sara L. Deschaine, Kimberly E. Whiting, Shelley N. Jackson, Maria Paula Cornejo, Mario Perello, Zhi-Bing You, Michael Eckhaus, Karuna Rasineni, Kim D. Janda, Barry Zorman, Pavel Sumazin, George F. Koob, Michael Michaelides, Pietro P. Sanna, Leandro F. Vendruscolo, Lorenzo Leggio
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract The stomach-derived hormone ghrelin regulates essential physiological functions. The ghrelin receptor (GHSR) has ligand-independent actions; therefore, GHSR gene deletion may be a reasonable approach to investigate the role of this system in
Externí odkaz:
https://doaj.org/article/69dd93baf3cc42269d69f72c7d7939c7
Autor:
Gabriel M. Aldridge, Tyler A. Zarin, Adam J. Brandner, Olivier George, Nicholas W. Gilpin, Vez Repunte-Canonigo, Pietro Paolo Sanna, George F. Koob, Leandro F. Vendruscolo, Brooke E. Schmeichel
Publikováno v:
Addiction Neuroscience, Vol 3, Iss , Pp 100028- (2022)
Hypocretin/orexin (HCRT) is a neuropeptide that is associated with both stress and reward systems in humans and rodents. The different contributions of signaling at hypocretin-receptor 1 (HCRT-R1) and hypocretin-receptor 2 (HCRT-R2) to compulsive alc
Externí odkaz:
https://doaj.org/article/0102601559f9496a88821ff6621d586a
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract To generate new mechanistic hypotheses on the pathogenesis and disease progression of neuroHIV and identify novel therapeutic targets to improve neuropsychological function in people with HIV, we investigated host genes and pathway dysregula
Externí odkaz:
https://doaj.org/article/9bc3cede3b05453f8acb25f9e3850cd8
Autor:
Jihuan Chen, Valerie Chen, Tomoya Kawamura, Ivy Hoang, Yang Yang, Ashley Tess Wong, Ryan McBride, Vez Repunte-Canonigo, Glenn L. Millhauser, Pietro Paolo Sanna
Publikováno v:
iScience, Vol 22, Iss , Pp 557-570 (2019)
Summary: The endogenous melanocortin peptide agouti-related protein (AgRP) plays a well-known role in foraging, but its contribution to metabolic regulation is less understood. Mature AgRP(83-132) has distinct residues for melanocortin receptor bindi
Externí odkaz:
https://doaj.org/article/baddd746410e4c5c9d5f58360f9fb654
Autor:
Yu Fu, Irene Lorrai, Barry Zorman, Daniele Mercatelli, Chase Shankula, Jorge Marquez Gaytan, Celine Lefebvre, Giordano de Guglielmo, Hyunjae Ryan Kim, Pavel Sumazin, Federico M. Giorgi, Vez Repunte-Canonigo, Pietro Paolo Sanna
Publikováno v:
Viruses, Vol 14, Iss 4, p 669 (2022)
Substance use disorder is associated with accelerated disease progression in people with human immunodeficiency virus (HIV; PWH). Problem opioid use, including high-dose opioid therapy, prescription drug misuse, and opioid abuse, is high and increasi
Externí odkaz:
https://doaj.org/article/ee90c1b0e34346a5b8bb2bbfdb6a25ca
Autor:
Jihuan Chen, Tomoya Kawamura, Manveen K. Sethi, Joseph Zaia, Vez Repunte-Canonigo, Pietro Paolo Sanna
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract Substance abuse is a pressing problem with few therapeutic options. The identification of addiction resilience factors is a potential strategy to identify new mechanisms that can be targeted therapeutically. Heparan sulfate (HS) is a linear
Externí odkaz:
https://doaj.org/article/00157ec978ec40258256ee7bb42d115d
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0203566 (2019)
Internal RNA modifications have been known for decades, however their roles in mRNA regulation have only recently started to be elucidated. Here we investigated the most abundant mRNA modification, N6-methyladenosine (m6A) in transcripts from the hip
Externí odkaz:
https://doaj.org/article/3254ec245f474fef874ab89cd59d8d28
Autor:
Rachel Hills, Jim A. Mossman, Andres M. Bratt-Leal, Ha Tran, Roy M. Williams, David G. Stouffer, Irina V. Sokolova, Pietro P. Sanna, Jeanne F Loring, Mariah J Lelos
Publikováno v:
Stem Cells and Development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40b0e4ad5ee7d888fd88196e0e7b314f
https://doi.org/10.1089/scd.2023.0043
https://doi.org/10.1089/scd.2023.0043
Autor:
Daniele Mercatelli, Nicola Balboni, Alessandro Palma, Emanuela Aleo, Pietro Paolo Sanna, Giovanni Perini, Federico Manuel Giorgi
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 177 (2021)
Neuroblastoma (NBL) is a pediatric cancer responsible for more than 15% of cancer deaths in children, with 800 new cases each year in the United States alone. Genomic amplification of the MYC oncogene family member MYCN characterizes a subset of high
Externí odkaz:
https://doaj.org/article/ac44d46839314cfc856c52f34d0f74fb
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175316 (2017)
The pathogenesis and nosology of HIV-associated neurological disease (HAND) remain incompletely understood. Here, to provide new insight into the molecular events leading to neurocognitive impairments (NCI) in HIV infection, we analyzed pathway dysre
Externí odkaz:
https://doaj.org/article/393da4f6e26f43cfa2f01bfa06ecee3b