Výsledky vyhledávání - "Pietro Magrone"

Investigation on the chemoenzymatic synthesis of threo- and erythro-β-hydroxy-l-glutamic acid derivatives

Autor: Sergio Riva, Carlo De Micheli, Pietro Magrone, Gabriella Roda, Francesca Sagui, Rachele Pizzoli

Publikováno v: Journal of molecular catalysis. B, Enzymatic
75 (2012): 27–34. doi:10.1016/j.molcatb.2011.11.004
info:cnr-pdr/source/autori:Sagui, Francesca; De Micheli, Carlo; Roda, Gabriella; Magrone, Pietro; Pizzoli, Rachele; Riva, Sergio/titolo:Investigation on the chemoenzymatic synthesis of threo-and erythro-beta-hydroxy-L-glutamic acid derivatives/doi:10.1016%2Fj.molcatb.2011.11.004/rivista:Journal of molecular catalysis. B, Enzymatic (Print)/anno:2012/pagina_da:27/pagina_a:34/intervallo_pagine:27–34/volume:75

A derivative of the malonic semialdehyde was transformed by means of a bioconversion catalyzed by the enzyme L-threonine aldolase from E. coli into a 6:4 epimeric mixture of two precursors of beta-hydroxy glutamic acid. The enzyme was selective for t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7280ce0525ce408edab5dda18cd0ddc8
https://doi.org/10.1016/j.molcatb.2011.11.004

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Synthesis of Enantiomerically Enriched Dimers of Vinylphenols by Tandem Action of Laccases and Lipases

Autor: Sergio Riva, Daniela Monti, Bruno Danieli, Stefania Caufin, Paolo Gavezzotti, Pietro Magrone, Cristina Navarra

Publikováno v: Advanced synthesis & catalysis
353 (2011): 2421–2430. doi:10.1002/adsc.201100413
info:cnr-pdr/source/autori:Gavezzotti, Paolo; Navarra, Cristina; Caufin, Stefania; Danieli, Bruno; Magrone, Pietro; Monti, Daniela; Riva, Sergio/titolo:Synthesis of Enantiomerically Enriched Dimers of Vinylphenols by Tandem Action of Laccases and Lipases/doi:10.1002%2Fadsc.201100413/rivista:Advanced synthesis & catalysis (Print)/anno:2011/pagina_da:2421/pagina_a:2430/intervallo_pagine:2421–2430/volume:353

The tandem use of laccases and lipases has been exploited for the simple preparative synthesis of enantiomerically enriched dimeric phenols. Laccase-catalyzed oxidation of isoeugenol (1) and vinylguaiacol (7) in biphasic systems gave as main products

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https://doi.org/10.1002/adsc.201100413

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Intramolecular 1,6-Addition to 2-Pyridones. Mechanism and Synthetic Scope

Autor: Ian Derrick, Timothy Gallagher, Claire A. Haseler, Patrick M Durkin, Christoph Hirschhäuser, Pietro Magrone

Publikováno v: The Journal of Organic Chemistry. 75:3766-3774

The scope and limitations of the intramolecular 1,6-addition of an enolate to a 2-pyridone moiety, a reaction that has found application in the synthesis of the lupin alkaloids, have been probed. This nucleophilic addition process has been shown to b

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https://doi.org/10.1021/jo100514a

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Epiboxidine and novel-related analogues: A convenient synthetic approach and estimation of their affinity at neuronal nicotinic acetylcholine receptor subtypes

Autor: Cecilia Gotti, Pietro Magrone, Francesco Clementi, Clelia Dallanoce, Carlo Matera, Luca Rizzi, Luca Pucci, Marco De Amici

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 18:4651-4654

Racemic exo-epiboxidine 3, endo-epiboxidine 6, and the two unsaturated epiboxidine-related derivatives 7 and 8 were efficiently prepared taking advantage of a palladium-catalyzed Stille coupling as the key step in the reaction sequence. The target co

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https://doi.org/10.1016/j.bmcl.2008.07.016

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Lactam Enolate-Pyridone Addition: Synthesis of 4-Halocytisines

Autor: Timothy Gallagher, Pietro Magrone, Patrick M Durkin, Stella Matthews, Clelia Dallanoce

Publikováno v: Synlett. 2010:2789-2791

The application of a lactam enolate-pyridone addition sequence, originally developed for cytisine, has been applied successfully to generate the first examples of 4-halocytisines. Variation of the lactam component provides cyfusine and 4-fluorocyfusi

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https://doi.org/10.1055/s-0030-1259006

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Atovaquone-Statine 'Double-Drugs' with High Antiplasmodial Activity

Autor: Mario Dell'Agli, Silvia Parapini, Donatella Taramelli, Nadia Vaiana, Sergio Romeo, G. Galli, Anna Sparatore, Enrica Bosisio, Pietro Magrone

Publikováno v: ChemMedChem. 3:418-420

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https://doi.org/10.1002/cmdc.200700166

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Symmetric and asymmetric bolaamphiphiles from ascorbic acid

Autor: Christian Dolle, Emiliano Fratini, Pietro Magrone, Sergio Riva, Niccolò Peruzzi, Moira Ambrosi, Pierandrea Lo Nostro

Publikováno v: The journal of physical chemistry. B 115 (2011): 11638–11649. doi:10.1021/jp204920y
info:cnr-pdr/source/autori:Dolle, Christian; Magrone, Pietro; Riva, Sergio; Ambrosi, Moira; Fratini, Emiliano; Peruzzi, Niccolo; Lo Nostro, Pierandrea/titolo:Symmetric and Asymmetric Bolaamphiphiles from Ascorbic Acid/doi:10.1021%2Fjp204920y/rivista:The journal of physical chemistry. B/anno:2011/pagina_da:11638/pagina_a:11649/intervallo_pagine:11638–11649/volume:115

The properties of novel bolaamphiphiles that carry epimers of vitamin C (L-ascorbic acid and/or D-isoascorbic acid) as hydrophilic head groups, and an interconnecting aliphatic C(12) chain (DD, DL, and LL) were investigated by differential scanning c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20d2559d5af56655d248bab55e51ef9
https://pubmed.ncbi.nlm.nih.gov/21894932

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Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Δ2-isoxazoline derivatives as potent and selective agonists of α7 nicotinic acetylcholine receptors

Autor: Fabio Frigerio, Carlo De Micheli, Sergio Fucile, Clelia Dallanoce, Pietro Magrone, Vanessa Piccari, Francesco Clementi, Marco De Amici, Karla Frydenvang, Giovanni Grazioso, Cecilia Gotti, Carlo Matera, Luca Pucci

Publikováno v: ChemMedChem. 6(5)

A set of racemic spirocyclic quinuclidinyl-Δ(2)-isoxazoline derivatives was synthesized using a 1,3-dipolar cycloaddition-based approach. Target compounds were assayed for binding affinity toward rat neuronal homomeric (α7) and heteromeric (α4β2)

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https://pubmed.ncbi.nlm.nih.gov/21365765

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Exploiting enzymatic regioselectivity: a facile methodology for the synthesis of polyhydroxylated hybrid compounds

Autor: Walter Panzeri, Pietro Magrone, Sergio Riva, Daniele Passarella, Francesco Cavallo

Publikováno v: Organic & biomolecular chemistry 8 (2010): 5583–5590. doi:10.1039/c0ob00304b
info:cnr-pdr/source/autori:Magrone P.; Cavallo, F.; Panzeri, W.; Passerella, D.; Riva, S./titolo:Exploiting enzymatic regioselectivity: a facile methodology for the synthesis of polyhydroxylated hybrid compounds/doi:10.1039%2Fc0ob00304b/rivista:Organic & biomolecular chemistry/anno:2010/pagina_da:5583/pagina_a:5590/intervallo_pagine:5583–5590/volume:8

Polyhydroxylated hybrid molecules have been synthesized using a protocol based on the regioselective acylation of the target compounds with activated dicarboxylic acids catalyzed by Novozym-435. The procedure implies that the mixed ester derivatives

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1125ef175de9b25d17cac0773e1955
https://publications.cnr.it/doc/17745

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