Aging- and Senescence-associated Changes of Mesenchymal Stromal Cells in Myelodysplastic Syndromes

Autor: Domenico Mattiucci, Giulia Maurizi, Pietro Leoni, Antonella Poloni

Publikováno v: Cell Transplantation, Vol 27 (2018)

Hematopoietic stem and progenitor cells reside within the bone marrow (BM) microenvironment. By a well-balanced interplay between self-renewal and differentiation, they ensure a lifelong supply of mature blood cells. Physiologically, multiple differe

Externí odkaz: https://doaj.org/article/7b110737520b494f84cf1f4744c768fe

Primary B-cell lymphoblastic lymphoma of the testis

Autor: Flavia Tombolini, Vito Lacetera, Guido Gini, Debora Capelli, Pietro Leoni, Rodolfo Montironi, Andrea Benedetto Galosi, Giovanni Muzzonigro

Publikováno v: Archivio Italiano di Urologia e Andrologia, Vol 86, Iss 4, Pp 400-401 (2014)

We present a rare case of primary lymphoblastic B-cell lymphoma of the testis focusing on ultrasonographic and pathological features and clinical implications. Pathological examination revealed primary testicular lymphoblastic B-cell lymphoma which w

Externí odkaz: https://doaj.org/article/8a7e6415f63f457d95b2c75da9e47960

Pegylated liposomal doxorubicin in the treatment of primary cutaneous T-cell lymphomas

Autor: Stefano Pulini, Serena Rupoli, Gaia Goteri, Nicola Pimpinelli, Renato Alterini, Angela Tassetti, Anna Rita Scortechini, Massimo Offidani, Simonetta Mulattieri, Andrea Stronati, Giuliano Brandozzi, Alfredo Giacchetti, Giorgio Mozzicafreddo, Giuseppe Ricotti, Giorgio Filosa, Alberta Bettacchi, Marco Simonacci, Nicolino Novelli, Pietro Leoni

Publikováno v: Haematologica, Vol 92, Iss 5 (2007)

Pegylated liposomal doxorubicin (Peg-Doxo) is a promising drug for advanced/recalcitrant primary cutaneous T-cell lymphomas (CTCLs). This prospective phase II trial enrolled 19 patients. We observed overall and complete response rates of 84.2% and 42

Externí odkaz: https://doaj.org/article/5de4c33aef5a44beb348edcaf55d6f7c

Bortezomib, thalidomide, and dexamethasone followed by double autologous haematopoietic stem-cell transplantation for newly diagnosed multiple myeloma (GIMEMA-MMY-3006): long-term follow-up analysis of a randomised phase 3, open-label study

Autor: Paola Tacchetti, Lucia Pantani, Francesca Patriarca, Maria Teresa Petrucci, Elena Zamagni, Luca Dozza, Monica Galli, Francesco Di Raimondo, Claudia Crippa, Mario Boccadoro, Simona Barbato, Patrizia Tosi, Franco Narni, Vittorio Montefusco, Nicoletta Testoni, Antonio Spadano, Carolina Terragna, Norbert Pescosta, Giulia Marzocchi, Claudia Cellini, Piero Galieni, Sonia Ronconi, Marco Gobbi, Lucio Catalano, Antonio Lazzaro, Giovanni De Sabbata, Clotilde Cangialosi, Fabrizio Ciambelli, Pellegrino Musto, Francesca Elice, Michele Cavo, Renato Fanin, Roberto Foa', Alessandro Rambaldi, Giuseppe Rossi, Pietro Leoni, Paolo Corradini, Giuseppe Torelli, Giuseppe Fioritoni, Sergio Cortelazzo, Giorgio Lambertenghi Deliliers, Giorgio La Nasa, Alfonso Zaccaria, Paolo De Fabritiis, Nicola Cascavilla, Alberto Bosi, Gianpietro Semenzato, Luigi Gugliotta, Filippo Gherlinzoni, Emanuele Angelucci, Massimo Fabrizio Martelli, Maria Concetta Petti, Giuseppe Leone, Angelo Michele Carella, Fabio Ciceri, Armando Santoro, Felicetto Ferrara, Francesco Nobile, Alfonso Maria D'Arco, Alessandro Levis, Luciano Guardigni, Andrea Gallamini, Pier Paolo Fattori, Sergio Morandi, Dino Amadori, Bruno Rotoli, Salvatore Mirto, Giorgio Paladini, Ruggero Mozzana, Graziella Pinotti, Francesco Rodeghiero, Nicola Cantore, Vincenzo Pavone, Enrico Maria Pogliani, Anna Marina Liberati, Ignazio Majolino, Sergio Amadori, Francesco Lauria, Massimo Aglietta, Giovanni Quarta, Sergio Storti, Fortunato Morabito, Silvana Franca Capalbo, Alessandro Massimo Gianni, Vincenzo Mettivier, Vittorio Rizzoli, Carlo Bernasconi, Giuseppe Visani, Michele Pizzuti, Giacinto La Verde, Giuseppe Avvisati, Maurizio Longinotti, Eugenio Gallo, Franco Dammacco, Domenico Russo, Andrea Bacigalupo, Caterina Musolino

Publikováno v: The Lancet Haematology. 7:e861-e873

Background: The phase 3 GIMEMA-MMY-3006 trial, which compared bortezomib, thalidomide, and dexamethasone (VTD) combination therapy with thalidomide and dexamethasone (TD) as induction therapy before and consolidation therapy after double autologous h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d247cf6931cb796a2568e2552250ca02
https://doi.org/10.1016/s2352-3026(20)30323-9

Feasibility and Outcome of a Phase II Study of Intensive Induction Chemotherapy in 91 Elderly Patients with AML Evaluated Using a Simplified Multidimensional Geriatric Assessment

Autor: Francesco Saraceni, Attilio Olivieri, Debora Capelli, Pietro Leoni, Giancarlo Discepoli, Diego Menotti, Martina Chiarucci, Antonella Poloni, Alessandro Fiorentini

Publikováno v: Advances in Therapy

Introduction We prospectively tested in a phase II study high-dose aracytin and idarubicin plus amifostine as induction regimen in 149 patients with acute myeloid leukaemia (AML) aged ≥ 60 years, evaluated by a simplified multidimensional geriatric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d019799bf3fa1e33b0323b8fe624da83
https://doi.org/10.1007/s12325-020-01310-4