Výsledky vyhledávání - "Pietro L. Vernazza"

Akademický článek

Long-lasting protection of activity of nucleoside reverse transcriptase inhibitors and protease inhibitors (PIs) by boosted PI containing regimens.

Autor: Alexandra U Scherrer, Jürg Böni, Sabine Yerly, Thomas Klimkait, Vincent Aubert, Hansjakob Furrer, Alexandra Calmy, Matthias Cavassini, Luigia Elzi, Pietro L Vernazza, Enos Bernasconi, Bruno Ledergerber, Huldrych F Günthard, Swiss HIV Cohort Study (SHCS)

Publikováno v: PLoS ONE, Vol 7, Iss 11, p e50307 (2012)

BACKGROUND: The accumulation of mutations after long-lasting exposure to a failing combination antiretroviral therapy (cART) is problematic and severely reduces the options for further successful treatments. METHODS: We studied patients from the Swis

Externí odkaz: https://doaj.org/article/5e1eada09e7d4740901e16df03ee79d3

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HIV-1 Transmission During Recent Infection and During Treatment Interruptions as Major Drivers of New Infections in the Swiss HIV Cohort Study

Autor: Alex, Marzel, Mohaned, Shilaih, Wan-Lin, Yang, Jürg, Böni, Sabine, Yerly, Thomas, Klimkait, Vincent, Aubert, Dominique L, Braun, Alexandra, Calmy, Hansjakob, Furrer, Matthias, Cavassini, Manuel, Battegay, Pietro L, Vernazza, Enos, Bernasconi, Huldrych F, Günthard, Roger D, Kouyos, V, Aubert, M, Battegay, E, Bernasconi, J, Böni, H C, Bucher, C, Burton-Jeangros, A, Calmy, M, Cavassini, G, Dollenmaier, M, Egger, L, Elzi, J, Fehr, J, Fellay, H, Furrer, C A, Fux, M, Gorgievski, H F, Günthard, D, Haerry, B, Hasse, H H, Hirsch, M, Hoffmann, I, Hösli, C, Kahlert, L, Kaiser, O, Keiser, T, Klimkait, R D, Kouyos, H, Kovari, B, Ledergerber, G, Martinetti, B Martinez, de Tejada, K, Metzner, N, Müller, D, Nadal, D, Nicca, G, Pantaleo, A, Rauch, S, Regenass, M, Rickenbach, C, Rudin, F, Schöni-Affolter, P, Schmid, J, Schüpbach, R, Speck, P, Tarr, A, Trkola, P L, Vernazza, R, Weber, S, Yerly

Publikováno v: Clinical Infectious Diseases, Vol. 62, No 1 (2016) pp. 115-122
Marzel, Alex; Shilaih, Mohaned; Yang, Wan-Lin; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Aubert, Vincent; Braun, Dominique L; Calmy, Alexandra; Furrer, Hansjakob; Cavassini, Matthias; Battegay, Manuel; Vernazza, Pietro L; Bernasconi, Enos; Günthard, Huldrych F; Kouyos, Roger D (2016). HIV-1 Transmission During Recent Infection and During Treatment Interruptions as Major Drivers of New Infections in the Swiss HIV Cohort Study. Clinical infectious diseases, 62(1), pp. 115-122. Oxford University Press 10.1093/cid/civ732

BACKGROUND Reducing the fraction of transmissions during recent human immunodeficiency virus (HIV) infection is essential for the population-level success of "treatment as prevention". METHODS A phylogenetic tree was constructed with 19 604 Swiss seq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833646a754db9dc1fb6ed847d10179a8
https://archive-ouverte.unige.ch/unige:110040

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Limited clinical benefit of minority K103N and Y181C-variant detection in addition to routine genotypic resistance testing in antiretroviral therapy-naive patients

Autor: Karin J, Metzner, Alexandra U, Scherrer, Viktor, von Wyl, Jürg, Böni, Sabine, Yerly, Thomas, Klimkait, Vincent, Aubert, Hansjakob, Furrer, Hans H, Hirsch, Pietro L, Vernazza, Matthias, Cavassini, Alexandra, Calmy, Enos, Bernasconi, Rainer, Weber, Huldrych F, Günthard, S, Yerly

Publikováno v: Metzner, Karin J.; Scherrer, Alexandra U.; Von Wyl, Viktor; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Aubert, Vincent; Furrer, Hansjakob; Hirsch, Hans H.; Vernazza, Pietro L.; Cavassini, Matthias; Calmy, Alexandra; Bernasconi, Enos; Weber, Rainer; Günthard, Huldrych F. (2014). Limited clinical benefit of minority K103N and Y181C-variant detection in addition to routine genotypic resistance testing in antiretroviral therapy-naive patients. AIDS, 28(15), pp. 2231-2239. Lippincott Williams & Wilkins 10.1097/QAD.0000000000000397
AIDS, Vol. 28, No 15 (2014) pp. 2231-9

OBJECTIVE: The presence of minority nonnucleoside reverse transcriptase inhibitor (NNRTI)-resistant HIV-1 variants prior to antiretroviral therapy (ART) has been linked to virologic failure in treatment-naive patients. DESIGN: We performed a large re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a83cdf18432fcfc4ee8249bf1775588
https://boris.unibe.ch/54921/1/00002030-900000000-98279.pdf

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Social Meets Molecular: Combining Phylogenetic and Latent Class Analyses to Understand HIV-1 Transmission in Switzerland

Autor: Dorita Avila, Olivia Keiser, Matthias Egger, Roger Kouyos, Jürg Böni, Sabine Yerly, Thomas Klimkait, Pietro L. Vernazza, Vincent Aubert, Andri Rauch, Sebastian Bonhoeffer, Huldrych F. Günthard, Tanja Stadler, Ben D. Spycher, V. Aubert, J. Barth, M. Battegay, E. Bernasconi, J. Böni, H. C. Bucher, C. Burton-Jeangros, A. Calmy, M. Cavassini, M. Egger, L. Elzi, J. Fehr, J. Fellay, H. Furrer, C. A. Fux, M. Gorgievski, H. Günthard, D. Haerry, B. Hasse, H. H. Hirsch, I. Hösli, C. Kahlert, L. Kaiser, O. Keiser, T. Klimkait, R. Kouyos, H. Kovari, B. Ledergerber, G. Martinetti, B. Martinez de Tejada, K. Metzner, N. Müller, D. Nadal, G. Pantaleo, A. Rauch, S. Regenass, M. Rickenbach, C. Rudin, F. Schöni-Affolter, P. Schmid, D. Schultze, J. Schüpbach, R. Speck, C. Staehelin, P. Tarr, A. Telenti, A. Trkola, P. Vernazza, R. Weber, S. Yerly

Publikováno v: Avila, Dorita; Keiser, Olivia; Egger, Matthias; Kouyos, Roger; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Vernazza, Pietro L; Aubert, Vincent; Rauch, Andri; Bonhoeffer, Sebastian; Günthard, Huldrych F; Stadler, Tanja; Spycher, Ben D (2014). Social Meets Molecular: Combining Phylogenetic and Latent Class Analyses to Understand HIV-1 Transmission in Switzerland. American journal of epidemiology, 179(12), pp. 1514-1525. Oxford University Press 10.1093/aje/kwu076
AMERICAN JOURNAL OF EPIDEMIOLOGY
American Journal of Epidemiology, Vol. 179, No 12 (2014) pp. 1514-1525
American journal of epidemiology

Switzerland has a complex human immunodeficiency virus (HIV) epidemic involving several populations. We examined transmission of HIV type 1 (HIV 1) in a national cohort study. Latent class analysis was used to identify socioeconomic and behavioral gr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f50d23c752fd3acb1107b4091dc43962

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Higher risk of incident hepatitis C virus coinfection among men who have sex with men, in whom the HIV genetic bottleneck at transmission was wide

Autor: Roger D, Kouyos, Andri, Rauch, Dominique L, Braun, Wan-Lin, Yang, Jürg, Böni, Sabine, Yerly, Thomas, Klimkait, Vincent, Aubert, Cyril, Shah, Helen, Kovari, Alexandra, Calmy, Matthias, Cavassini, Manuel, Battegay, Pietro L, Vernazza, Enos, Bernasconi, Bruno, Ledergerber, Huldrych F, Günthard, S, Yerly

Publikováno v: The Journal of Infectious Diseases, Vol. 210, No 10 (2014) pp. 1555-61
Journal of Infectious Diseases, vol. 210, no. 10, pp. 1555-1561
The Journal of infectious diseases
JOURNAL OF INFECTIOUS DISEASES

BACKGROUND: High-risk sexual behaviors have been suggested as drivers of the recent dramatic increase of sexually transmitted hepatitis C virus (HCV) among human immunodeficiency virus (HIV)-infected men who have sex with men (MSM). METHODS: We asses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7140f1bc44ebf6ddfbd299a920c54246
https://archive-ouverte.unige.ch/unige:74399

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Higher CNS penetration-effectiveness of long-term combination antiretroviral therapy is associated with better HIV-1 viral suppression in cerebrospinal fluid

Autor: Alexia, Cusini, Pietro L, Vernazza, Sabine, Yerly, Laurent A, Decosterd, Bruno, Ledergerber, Christoph A, Fux, Janine, Rohrbach, Nicolas, Widmer, Bernhard, Hirschel, Roman, Gaudenz, Matthias, Cavassini, Thomas, Klimkait, Franziska, Zenger, Chistine, Gutmann, Milos, Opravil, Huldyrich F, Günthard, S, Yerly

Publikováno v: Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, Vol. 62, No 1 (2013) pp. 28-35

Objectives: To determine HIV-1 RNA in cerebrospinal fluid (CSF) of successfully treated patients and to evaluate if combination antiretroviral treatments with higher central nervous system penetration-effectiveness (CPE) achieve better CSF viral supp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69ea5966e74f36ca5a297559404ddb2
https://pubmed.ncbi.nlm.nih.gov/24135736

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Minor protease inhibitor mutations at baseline do not increase the risk for a virological failure in HIV-1 subtype B infected patients

Autor: Alexandra U Scherrer, Bruno Ledergerber, Viktor von Wyl, Jürg Böni, Sabine Yerly, Thomas Klimkait, Cristina Cellerai, Hansjakob Furrer, Alexandra Calmy, Matthias Cavassini, Luigia Elzi, Pietro L Vernazza, Enos Bernasconi, Huldrych F Günthard, Swiss HIV Cohort Study

Publikováno v: PLOS ONE, Vol. 7, No 6 (2012) P. e37983
PLoS ONE, Vol 7, Iss 6, p e37983 (2012)
PLoS ONE; Vol 7
PloS one
PLoS ONE
Scherrer, Alexandra U.; Ledergerber, Bruno; von Wyl, Viktor; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Cellerai, Cristina; Furrer, Hansjakob; Calmy, Alexandra; Cavassini, Matthias; Elzi, Luigia; Vernazza, Pietro L.; Bernasconi, Enos; Günthard, Huldrych F.; Swiss HIV Cohort Study, (2012). Minor protease inhibitor mutations at baseline do not increase the risk for a virological failure in HIV-1 subtype B infected patients. PLoS ONE, 7(6), e37983. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0037983
Plos One, vol. 7, no. 6, pp. e37983

Background Minor protease inhibitor (PI) mutations often exist as polymorphisms in HIV-1 sequences from treatment-naive patients. Previous studies showed that their presence impairs the antiretroviral treatment (ART) response. Evaluating these findin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7322ddc0fddb37cfc7322f0a1a05e5f5
https://doi.org/10.5167/uzh-67852

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Viral suppression rates in salvage treatment with raltegravir improved with the administration of genotypic partially active or inactive nucleoside/tide reverse transcriptase inhibitors

Autor: Alexandra U, Scherrer, Viktor, von Wyl, Jürg, Böni, Sabine, Yerly, Thomas, Klimkait, Philippe, Bürgisser, Christian, Garzoni, Bernard, Hirschel, Matthias, Cavassini, Manuel, Battegay, Pietro L, Vernazza, Enos, Bernasconi, Bruno, Ledergerber, Huldrych F, Günthard, S, Yerly

Publikováno v: JAIDS Journal of Acquired Immune Deficiency Syndromes; Vol 57
Journal of Acquired Immune Deficiency Syndromes, Vol. 57, No 1 (2011) pp. 24-31

Nucleoside reverse transcriptase inhibitors (NRTIs) are often administered in salvage therapy even if genotypic resistance tests (GRTs) indicate high-level resistance, but little is known about the benefit of these additional NRTIs.The effect of2 com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d05a906eb639a08737fd6d4dde3b97
https://pubmed.ncbi.nlm.nih.gov/21921728

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