Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Pietro L. Poliani"'
Autor:
Francesca De Bacco, Francesca Orzan, Giovanni Crisafulli, Marta Prelli, Claudio Isella, Elena Casanova, Raffaella Albano, Gigliola Reato, Jessica Erriquez, Antonio D’Ambrosio, Mara Panero, Carmine Dall’Aglio, Laura Casorzo, Manuela Cominelli, Francesca Pagani, Antonio Melcarne, Pietro Zeppa, Roberto Altieri, Isabella Morra, Paola Cassoni, Diego Garbossa, Anna Cassisa, Alice Bartolini, Serena Pellegatta, Paolo M. Comoglio, Gaetano Finocchiaro, Pietro L. Poliani, Carla Boccaccio
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112816- (2023)
Summary: Glioblastoma (GBM) is known as an intractable, highly heterogeneous tumor encompassing multiple subclones, each supported by a distinct glioblastoma stem cell (GSC). The contribution of GSC genetic and transcriptional heterogeneity to tumor
Externí odkaz:
https://doaj.org/article/62de693a508141dda55e45a585a9e8e1
Autor:
Valentina Conti, Manuela Cominelli, Valentina Pieri, Alberto L. Gallotti, Ilaria Pagano, Matteo Zanella, Stefania Mazzoleni, Flavia Pivetta, Monica Patanè, Giulia M. Scotti, Ignazio S. Piras, Bianca Pollo, Andrea Falini, Alessio Zippo, Antonella Castellano, Roberta Maestro, Pietro L. Poliani, Rossella Galli
Publikováno v:
JCI Insight, Vol 6, Iss 23 (2021)
Medulloblastoma (MB), one of the most malignant brain tumors of childhood, comprises distinct molecular subgroups, with p53 mutant sonic hedgehog–activated (SHH-activated) MB patients having a very severe outcome that is associated with unfavorable
Externí odkaz:
https://doaj.org/article/50c5ba30db8f477f8318eacf4e00e7f0
Autor:
Rossella Galli, Annapaola Andolfo, Rosa Maria Moresco, Pietro L. Poliani, Alessio Zippo, Andrea Falini, Antonella Castellano, Antonello Spinelli, Laura Perani, Federica Ungaro, Luca Massimino, Daniela Michelatti, Sara Lago, Angela Coliva, Silvia Valtorta, Valentina Conti, Ilaria Pagano, Manuela Cominelli, Denise Drago, Alberto L. Gallotti, Valentina Pieri
Supplementary Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d0c463f21c61a64334e8400287b2448
https://doi.org/10.1158/0008-5472.22433114.v1
https://doi.org/10.1158/0008-5472.22433114.v1
Autor:
Rossella Galli, Annapaola Andolfo, Rosa Maria Moresco, Pietro L. Poliani, Alessio Zippo, Andrea Falini, Antonella Castellano, Antonello Spinelli, Laura Perani, Federica Ungaro, Luca Massimino, Daniela Michelatti, Sara Lago, Angela Coliva, Silvia Valtorta, Valentina Conti, Ilaria Pagano, Manuela Cominelli, Denise Drago, Alberto L. Gallotti, Valentina Pieri
Glioblastoma (GBM) is a common and deadly form of brain tumor in adults. Dysregulated metabolism in GBM offers an opportunity to deploy metabolic interventions as precise therapeutic strategies. To identify the molecular drivers and the modalities by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39e5ea3e55bd5ff073026aae1ca16d36
https://doi.org/10.1158/0008-5472.c.6514307.v1
https://doi.org/10.1158/0008-5472.c.6514307.v1
Autor:
Rossella Galli, Pietro L. Poliani, Alessandro Bulfone, Michele De Palma, Andrea Falini, Lucia Sergi Sergi, Alberto Franzin, Manuela Cominelli, Mauro Pala, Letterio S. Politi, Stefania Mazzoleni
Supplementary Figures 1-9, Tables 1-4, Methods and Materials from Epidermal Growth Factor Receptor Expression Identifies Functionally and Molecularly Distinct Tumor-Initiating Cells in Human Glioblastoma Multiforme and Is Required for Gliomagenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5b8a5bb0895e56d1c8ea057cb613f2
https://doi.org/10.1158/0008-5472.22388564.v1
https://doi.org/10.1158/0008-5472.22388564.v1
Autor:
Francesca De Bacco, Antonio D'Ambrosio, Elena Casanova, Francesca Orzan, Roberta Neggia, Raffaella Albano, Federica Verginelli, Manuela Cominelli, Pietro L Poliani, Paolo Luraghi, Gigliola Reato, Serena Pellegatta, Gaetano Finocchiaro, Timothy Perera, Elisabetta Garibaldi, Pietro Gabriele, Paolo M Comoglio, Carla Boccaccio
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 5, Pp 550-568 (2016)
Abstract Glioblastoma (GBM) contains stem‐like cells (GSCs) known to be resistant to ionizing radiation and thus responsible for therapeutic failure and rapidly lethal tumor recurrence. It is known that GSC radioresistance relies on efficient activ
Externí odkaz:
https://doaj.org/article/e3a220eeaa804cb09dc87829df92d2bd
Autor:
Valentina Pieri, Alberto L. Gallotti, Denise Drago, Manuela Cominelli, Ilaria Pagano, Valentina Conti, Silvia Valtorta, Angela Coliva, Sara Lago, Daniela Michelatti, Luca Massimino, Federica Ungaro, Laura Perani, Antonello Spinelli, Antonella Castellano, Andrea Falini, Alessio Zippo, Pietro L. Poliani, Rosa Maria Moresco, Annapaola Andolfo, Rossella Galli
Publikováno v:
Cancer research.
Glioblastoma (GBM) is a common and deadly form of brain tumor in adults. Dysregulated metabolism in GBM offers an opportunity to deploy metabolic interventions as precise therapeutic strategies. To identify the molecular drivers and the modalities by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e7041a08d4a5de79d2ec5b710c8a65
https://pubmed.ncbi.nlm.nih.gov/36409826
https://pubmed.ncbi.nlm.nih.gov/36409826
Autor:
Anna Villa, Marita Bosticardo, Maria Carmina Castiello, Francesca Pala, Lucia Sereni, Elena Draghici, Donato Inverso, Aisha V. Sauer, Francesca Schena, Elena Fontana, Enrico Radaelli, Paolo Uva, Karla E. Cervantes-Luevano, Federica Benvenuti, Pietro L. Poliani, Matteo Iannacone, Elisabetta Traggiai
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Wiskott–Aldrich syndrome (WAS) is a primary immunodeficiency caused by mutations in the gene encoding the hematopoietic-specific WAS protein (WASp). WAS is frequently associated with autoimmunity, indicating a critical role of WASp in maintenance o
Externí odkaz:
https://doaj.org/article/c14f7a2eaf3f45258aa3ece941eee02d
Autor:
Yingyue Zhou, Wilbur M. Song, Prabhakar Andhey, Amanda Swain, Tyler Levy, Kelly R Miller, Pietro L. Poliani, Manuela Cominelli, Shikha Grover, Susan Gilfillan, Marina Cella, Tyler K Ulland, Konstantin Zaitsev, Akinori Miyashita, Takeshi Ikeuchi, Makoto Sainouchi, Akiyoshi Kakita, David A Bennett, Julie A Schneider, Michael R Nichols, Sean A Beausoleil, Jason Ulrich, David M Holtzman, Maxim Artyomov, Marco Colonna
Publikováno v:
Nature medicine
Alzheimer’s disease (AD) is the most common form of dementia that is initiated by extracellular plaque deposition and intraneuronal hyperphosphorylated tau aggregates. Reactive astrocytosis and microgliosis are secondary cellular responses to patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d07f6a73a56aa58325a309974ff812
http://europepmc.org/articles/PMC6980793
http://europepmc.org/articles/PMC6980793
Autor:
Shoutang Wang, Raki Sudan, Vincent Peng, Yingyue Zhou, Siling Du, Carla M. Yuede, Tingting Lei, Jinchao Hou, Zhangying Cai, Marina Cella, Khai Nguyen, Pietro L. Poliani, Wandy L. Beatty, Yun Chen, Siyan Cao, Kent Lin, Cecilia Rodrigues, Ali H. Ellebedy, Susan Gilfillan, Gordon D. Brown, David M. Holtzman, Simone Brioschi, Marco Colonna
Publikováno v:
Cell. 185(22)
Genetic studies have highlighted microglia as pivotal in orchestrating Alzheimer's disease (AD). Microglia that adhere to Aβ plaques acquire a transcriptional signature, "disease-associated microglia" (DAM), which largely emanates from the TREM2-DAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2518bade01cf27e82ea856c7902f272d
https://pubmed.ncbi.nlm.nih.gov/36306735
https://pubmed.ncbi.nlm.nih.gov/36306735