Increases in1H-NMR Mobile Lipids are not Always Associated with Overt Apoptosis: Evidence from MG-63 Human Osteosarcoma Three-Dimensional Spheroids Exposed to a Low Dose (2 Gy) of Ionizing Radiation

Autor: Pietro L. Indovina, Maria Teresa Santini, Antonella Ferrante, Andrea Motta, Gabriella Rainaldi, Rocco Romano

Publikováno v: Radiation research 165 (2006): 131–141. doi:10.1667/RR3500.1
info:cnr-pdr/source/autori:Santini, M. T.; Romano, R.; Rainaldi, G.; Ferrante, A.; Motta, A.; Indovina, P. L.;/titolo:Increases in 1H-NMR mobile lipids are not always associated with overt apoptosis: evidence from MG-63 human osteosarcoma three-dimensional spheroids exposed to a low dose (2 Gy) of ionizing radiation/doi:10.1667%2FRR3500.1/rivista:Radiation research/anno:2006/pagina_da:131/pagina_a:141/intervallo_pagine:131–141/volume:165

The metabolic changes that occur in MG-63 osteosarcoma three-dimensional tumor spheroids exposed to 2 Gy of ionizing radiation, a dose that is comparable to radiation therapy, were studied using high-resolution proton nuclear magnetic resonance ((1)H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1a7be368ae9664b4d297b58490897a
https://doi.org/10.1667/rr3500.1

The relationship between 1H-NMR mobile lipid intensity and cholesterol in two human tumor multidrug resistant cell lines (MCF-7 and LoVo)

Autor: Loredana Porcu, Pietro L. Indovina, Elena Bravo, Annarica Calcabrini, Maria Teresa Santini, Stefania Meschini, Giuseppe Arancia, Perla Filippini, Gabriella Rainaldi, Andrea Motta, Rocco Romano

Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1531:111-131

The high resolution proton nuclear magnetic resonance (1H-NMR) spectra of two different cell lines exhibiting multidrug resistance (MDR) as demonstrated by the expression of the well-known energy-driven, membrane-bound 170 kDa P-glycoprotein pump kno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f764beabe0786c789506f28f63e4ea2
https://doi.org/10.1016/s1388-1981(01)00093-2

Multicellular tumour spheroids in radiation biology

Autor: Pietro L. Indovina, Maria Teresa Santini, Gabriella Rainaldi

Publikováno v: International Journal of Radiation Biology. 75:787-799

Multicellular tumour spheroids are being used with increasing frequency in various aspects of tumour biology, including studies dealing with radiation biology. This review attempts to outline recent studies using these three-dimensional systems in ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf5065d37a1eefecbf9bffb99126c93
https://doi.org/10.1080/095530099139845

Fusinite as a specific probe for the determination of molecular oxygen concentration in cells

Autor: Pietro L. Indovina, Maria Teresa Santini, Walter Malorni, Silvia Paradisi, Elisabetta Straface, Carmine Zicari

Publikováno v: Biochimica et Biophysica Acta (BBA) - General Subjects. 1243:110-116

The feasibility of using EPR and the paramagnetic derivative of coal 'fusinite' to measure intracellular oxygen concentration in cultured cells in which this substance was internalized in the cytoplasm was examined. First, the possible cytotoxic effe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e306848db2bfd492a0e2051b2af283d1
https://doi.org/10.1016/0304-4165(94)00122-e

SAR measurement in MRI: an improved method

Autor: Fabrizio Barone, Pietro L. Indovina, Rocco Romano, Fausto Acernese

Publikováno v: SPIE Proceedings.

During an MR procedure, the patient absorbs a portion of the transmitted RF energy, which may result in tissue heating and other adverse effects, such as alterations in visual, auditory and neural functions. The Specific Absorption Rate (SAR), in W/k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22cd61780c2847e9e1867dd19892137
https://doi.org/10.1117/12.814127