Minor protease inhibitor mutations at baseline do not increase the risk for a virological failure in HIV-1 subtype B infected patients.

Autor: Alexandra U Scherrer, Bruno Ledergerber, Viktor von Wyl, Jürg Böni, Sabine Yerly, Thomas Klimkait, Cristina Cellerai, Hansjakob Furrer, Alexandra Calmy, Matthias Cavassini, Luigia Elzi, Pietro L Vernazza, Enos Bernasconi, Huldrych F Günthard, Swiss HIV Cohort Study

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e37983 (2012)

BACKGROUND: Minor protease inhibitor (PI) mutations often exist as polymorphisms in HIV-1 sequences from treatment-naïve patients. Previous studies showed that their presence impairs the antiretroviral treatment (ART) response. Evaluating these find

Externí odkaz: https://doaj.org/article/d9c8b2b4bddd40ffad55a20b5c7cdd7b

A comparison of initial antiretroviral therapy in the Swiss HIV Cohort Study and the recommendations of the International AIDS Society-USA.

Autor: Gilles Wandeler, Olivia Keiser, Bernard Hirschel, Huldrych F Günthard, Enos Bernasconi, Manuel Battegay, Olivier Clerc, Pietro L Vernazza, Hansjakob Furrer, Swiss HIV Cohort Study

Publikováno v: PLoS ONE, Vol 6, Iss 12, p e27903 (2011)

BACKGROUND: In order to facilitate and improve the use of antiretroviral therapy (ART), international recommendations are released and updated regularly. We aimed to study if adherence to the recommendations is associated with better treatment outcom

Externí odkaz: https://doaj.org/article/b2ae250130964b5487c41b967ba63ae9

HIV-1 Transmission During Recent Infection and During Treatment Interruptions as Major Drivers of New Infections in the Swiss HIV Cohort Study

Autor: Alex, Marzel, Mohaned, Shilaih, Wan-Lin, Yang, Jürg, Böni, Sabine, Yerly, Thomas, Klimkait, Vincent, Aubert, Dominique L, Braun, Alexandra, Calmy, Hansjakob, Furrer, Matthias, Cavassini, Manuel, Battegay, Pietro L, Vernazza, Enos, Bernasconi, Huldrych F, Günthard, Roger D, Kouyos, V, Aubert, M, Battegay, E, Bernasconi, J, Böni, H C, Bucher, C, Burton-Jeangros, A, Calmy, M, Cavassini, G, Dollenmaier, M, Egger, L, Elzi, J, Fehr, J, Fellay, H, Furrer, C A, Fux, M, Gorgievski, H F, Günthard, D, Haerry, B, Hasse, H H, Hirsch, M, Hoffmann, I, Hösli, C, Kahlert, L, Kaiser, O, Keiser, T, Klimkait, R D, Kouyos, H, Kovari, B, Ledergerber, G, Martinetti, B Martinez, de Tejada, K, Metzner, N, Müller, D, Nadal, D, Nicca, G, Pantaleo, A, Rauch, S, Regenass, M, Rickenbach, C, Rudin, F, Schöni-Affolter, P, Schmid, J, Schüpbach, R, Speck, P, Tarr, A, Trkola, P L, Vernazza, R, Weber, S, Yerly

Publikováno v: Clinical Infectious Diseases, Vol. 62, No 1 (2016) pp. 115-122
Marzel, Alex; Shilaih, Mohaned; Yang, Wan-Lin; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Aubert, Vincent; Braun, Dominique L; Calmy, Alexandra; Furrer, Hansjakob; Cavassini, Matthias; Battegay, Manuel; Vernazza, Pietro L; Bernasconi, Enos; Günthard, Huldrych F; Kouyos, Roger D (2016). HIV-1 Transmission During Recent Infection and During Treatment Interruptions as Major Drivers of New Infections in the Swiss HIV Cohort Study. Clinical infectious diseases, 62(1), pp. 115-122. Oxford University Press 10.1093/cid/civ732

BACKGROUND Reducing the fraction of transmissions during recent human immunodeficiency virus (HIV) infection is essential for the population-level success of "treatment as prevention". METHODS A phylogenetic tree was constructed with 19 604 Swiss seq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833646a754db9dc1fb6ed847d10179a8
https://archive-ouverte.unige.ch/unige:110040

Social Meets Molecular: Combining Phylogenetic and Latent Class Analyses to Understand HIV-1 Transmission in Switzerland

Autor: Dorita Avila, Olivia Keiser, Matthias Egger, Roger Kouyos, Jürg Böni, Sabine Yerly, Thomas Klimkait, Pietro L. Vernazza, Vincent Aubert, Andri Rauch, Sebastian Bonhoeffer, Huldrych F. Günthard, Tanja Stadler, Ben D. Spycher, V. Aubert, J. Barth, M. Battegay, E. Bernasconi, J. Böni, H. C. Bucher, C. Burton-Jeangros, A. Calmy, M. Cavassini, M. Egger, L. Elzi, J. Fehr, J. Fellay, H. Furrer, C. A. Fux, M. Gorgievski, H. Günthard, D. Haerry, B. Hasse, H. H. Hirsch, I. Hösli, C. Kahlert, L. Kaiser, O. Keiser, T. Klimkait, R. Kouyos, H. Kovari, B. Ledergerber, G. Martinetti, B. Martinez de Tejada, K. Metzner, N. Müller, D. Nadal, G. Pantaleo, A. Rauch, S. Regenass, M. Rickenbach, C. Rudin, F. Schöni-Affolter, P. Schmid, D. Schultze, J. Schüpbach, R. Speck, C. Staehelin, P. Tarr, A. Telenti, A. Trkola, P. Vernazza, R. Weber, S. Yerly

Publikováno v: Avila, Dorita; Keiser, Olivia; Egger, Matthias; Kouyos, Roger; Böni, Jürg; Yerly, Sabine; Klimkait, Thomas; Vernazza, Pietro L; Aubert, Vincent; Rauch, Andri; Bonhoeffer, Sebastian; Günthard, Huldrych F; Stadler, Tanja; Spycher, Ben D (2014). Social Meets Molecular: Combining Phylogenetic and Latent Class Analyses to Understand HIV-1 Transmission in Switzerland. American journal of epidemiology, 179(12), pp. 1514-1525. Oxford University Press 10.1093/aje/kwu076
AMERICAN JOURNAL OF EPIDEMIOLOGY
American Journal of Epidemiology, Vol. 179, No 12 (2014) pp. 1514-1525
American journal of epidemiology

Switzerland has a complex human immunodeficiency virus (HIV) epidemic involving several populations. We examined transmission of HIV type 1 (HIV 1) in a national cohort study. Latent class analysis was used to identify socioeconomic and behavioral gr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f50d23c752fd3acb1107b4091dc43962

Biological correlates of sexual transmission of HIV: practical consequences and potential targets for public health

Autor: Pietro L. Vernazza, Angela D. M. Kashuba, Myron S. Cohen

Publikováno v: Reviews in Medical Microbiology. 12:131-142

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::826e99b6c1ba3f135413cb65916db346
https://doi.org/10.1097/00013542-200107000-00002