Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Pietro Marini"'
Autor:
Mohammad Arastoo, Lewis K. Penny, Richard Lofthouse, Aya Abdallah, Anna Abrahamsson, Pietro Marini, Valeria Melis, Gernot Riedel, Charles R. Harrington, Claude M. Wischik, Andrew Porter, Soumya Palliyil
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Background Recent advances in blood-based biomarker discovery are paving the way for simpler, more accessible diagnostic tools that can detect early signs of Alzheimer’s disease (AD). Recent successes in the development of amyloid-targetin
Externí odkaz:
https://doaj.org/article/3efb8c85249a4d3e81c8e65617f504f9
Publikováno v:
Neurology International, Vol 16, Iss 4, Pp 776-789 (2024)
The relationship between nuclear factor erythroid 2-related factor 2 (Nrf2) and phytocannabinoids/endocannabinoids (pCBs/eCBs) has been investigated in a variety of models of peripheral illnesses, with little clarification on their interaction within
Externí odkaz:
https://doaj.org/article/a00b0d157b294df5bd47ba063984ef7f
Autor:
Thabat Khatib, Pietro Marini, Sudheer Nunna, David R. Chisholm, Andrew Whiting, Christopher Redfern, Iain R. Greig, Peter McCaffery
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-16 (2019)
Abstract Retinoic acid (RA) is the active metabolite of vitamin A and essential for many physiological processes, particularly the induction of cell differentiation. In addition to regulating genomic transcriptional activity via RA receptors (RARs) a
Externí odkaz:
https://doaj.org/article/330b2674541e4c07a9ef2d9a22ca6c3a
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3620
Volume 24
Issue 4
Pages: 3620
3-3′-Diindolylmethane (DIM) is a biologically active dimer derived from the endogenous conversion of indole-3-carbinol (I3C), a naturally occurring glucosinolate found in many cruciferous vegetables (i.e., Brassicaceae). DIM was the first pure andr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32388ad88baeaddaf7e77e131fc89791
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627273
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c6cf1a746f5c1782d156dffc3f6f618
https://doi.org/10.1007/978-1-0716-2728-0_8
https://doi.org/10.1007/978-1-0716-2728-0_8
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627273
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb354f849990ed5dcc17def5c0b9d363
https://doi.org/10.1007/978-1-0716-2728-0_13
https://doi.org/10.1007/978-1-0716-2728-0_13
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2576
The cyclic AMP assay is a functional assay that is commonly used to determine the pharmacological behavior (agonists, antagonists, and inverse agonists) of G-protein coupled receptor ligands. Here, we describe the cyclic AMP assay that is carried out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f66806b4fce264098cca176814e82ad
https://pubmed.ncbi.nlm.nih.gov/36152185
https://pubmed.ncbi.nlm.nih.gov/36152185
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2576
Displacement binding assays are nonfunctional assays mostly used with the aim of determining whether a certain compound (plant-derived or synthetic) can bind to a specific receptor with high affinity. Here, we describe the displacement binding assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b44e10d39f5056c424623beef40b259
https://pubmed.ncbi.nlm.nih.gov/36152180
https://pubmed.ncbi.nlm.nih.gov/36152180
Autor:
Pietro Marini, Philip Cowie, Ahmet Ayar, Guy S. Bewick, John Barrow, Roger G. Pertwee, Alasdair MacKenzie, Paolo Tucci
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1308
In this study, we have investigated a possible mechanism that enables CB1/M3 receptor cross-talk, using SH-SY5Y cells as a model system. Our results show that M3 receptor activation initiates signaling that rapidly upregulates the CNR1 gene, resultin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a81856e07377dd78a0ab30aaf4682a
https://doi.org/10.3390/ijms24021308
https://doi.org/10.3390/ijms24021308
Publikováno v:
Compass: Journal of Learning and Teaching. 13
Given the pace of technological change, today’s students need to be prepared for changing employment roles in an ever-evolving world. Increasingly, employers require graduates to be innovative, adaptable and resilient, and have an enterprising mind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f497c5099819741125a8c1bb129e360
https://doi.org/10.21100/compass.v13i2.1039
https://doi.org/10.21100/compass.v13i2.1039