Zobrazeno 1 - 10
of 2 560
pro vyhledávání: '"Pietiläinen, A"'
Autor:
Odnoblyudova, Arina, Hizli, Çağlar, John, ST, Cognolato, Andrea, Juuti, Anne, Särkkä, Simo, Pietiläinen, Kirsi, Marttinen, Pekka
In biomedical applications it is often necessary to estimate a physiological response to a treatment consisting of multiple components, and learn the separate effects of the components in addition to the joint effect. Here, we extend existing probabi
Externí odkaz:
http://arxiv.org/abs/2311.03129
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Introduction Healthcare professionals’ perspectives are often overlooked in the evaluation of digital weight loss interventions. Thus, we examined how healthcare professionals perceive patient success in a one-year web-based weight managem
Externí odkaz:
https://doaj.org/article/a29284470d2b4f53877fcd349d3f3d76
Deciding on an appropriate intervention requires a causal model of a treatment, the outcome, and potential mediators. Causal mediation analysis lets us distinguish between direct and indirect effects of the intervention, but has mostly been studied i
Externí odkaz:
http://arxiv.org/abs/2306.09656
Autor:
Heidi Kaihua, Ville Pietiläinen
Publikováno v:
Matkailututkimus, Vol 20, Iss 3 (2024)
Matkailualaan keskittyvää johtamistutkimusta on tehty kansainvälisesti ja pohjoismaissa. Tutkimusten painopiste on alan toimintaympäristön ja reunaehtojen tarkastelussa, jolloin johtamisilmiön tavoittaminen erilaisiin tilanteisiin sidonnaisena,
Externí odkaz:
https://doaj.org/article/088e33601dae4c45915eb1b91a6017d8
Publikováno v:
Data in Brief, Vol 57, Iss , Pp 111143- (2024)
The food service and restaurant industry play a crucial role in promoting sustainable food consumption by offering sustainable meal options, shaping consumer preferences, and introducing eco-friendly practices. To enable the food services operating i
Externí odkaz:
https://doaj.org/article/101b3618d7f14708aa61fde96255d460
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
Obesity is an important health concern that poses many public health challenges. Evidence-based treatment modalities, capable of cost-effectively reaching large patient groups are needed. In this paper, we present the design and methods of the update
Externí odkaz:
https://doaj.org/article/c17c733ade584f7e89703b58d634a62b
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-27 (2024)
Abstract Background Variation in X chromosome inactivation (XCI) in human-induced pluripotent stem cells (hiPSCs) can impact their ability to model biological sex biases. The gene-wise landscape of X chromosome gene dosage remains unresolved in femal
Externí odkaz:
https://doaj.org/article/948460aec0694b3eb9427830f6390bc9
A treatment policy defines when and what treatments are applied to affect some outcome of interest. Data-driven decision-making requires the ability to predict what happens if a policy is changed. Existing methods that predict how the outcome evolves
Externí odkaz:
http://arxiv.org/abs/2209.04142
Autor:
Seung Hyuk T. Lee, Kristina M. Garske, Uma Thanigai Arasu, Asha Kar, Zong Miao, Marcus Alvarez, Amogha Koka, Nicholas Darci-Maher, Jihane N. Benhammou, David Z. Pan, Tiit Örd, Dorota Kaminska, Ville Männistö, Sini Heinonen, Martin Wabitsch, Markku Laakso, Vatche G. Agopian, Joseph R. Pisegna, Kirsi H. Pietiläinen, Jussi Pihlajamäki, Minna U. Kaikkonen, Päivi Pajukanta
Publikováno v:
EBioMedicine, Vol 106, Iss , Pp 105232- (2024)
Summary: Background: Abdominal obesity increases the risk for non-alcoholic fatty liver disease (NAFLD), now known as metabolic dysfunction-associated steatotic liver disease (MASLD). Methods: To elucidate the directional cell-type level biological m
Externí odkaz:
https://doaj.org/article/a9ca2e74a8164304bf81b6dd03723f19
Autor:
Noora Räsänen, Jari Tiihonen, Marja Koskuvi, Šárka Lehtonen, Nelli Jalkanen, Nelli Karmila, Isabelle Weert, Olli Vaurio, Ilkka Ojansuu, Markku Lähteenvuo, Olli Pietiläinen, Jari Koistinaho
Publikováno v:
Biological Psychiatry Global Open Science, Vol 4, Iss 4, Pp 100313- (2024)
Background: Development of synaptic activity is a key neuronal characteristic that relies largely on interactions between neurons and astrocytes. Although astrocytes have known roles in regulating synaptic function and malfunction, the use of human-
Externí odkaz:
https://doaj.org/article/e7359c272ddf44e5beee97c07010e73c