Regional Expression Levels of Drug Transporters and Metabolizing Enzymes along the Pig and Human Intestinal Tract and Comparison with Caco-2 Cells.

Autor: Vaessen SF; TNO, Zeist, The Netherlands (M.M.H.L, C.A.M.K, H.M.W, E.S); Institute for Risk Assessment Sciences, Utrecht, The Netherlands (R.H.H.P, J.A.S,); Research Centre Technology & Innovation; and Innovative Testing in Life sciences and Chemistry, University of Applied Sciences, Utrecht, The Netherlands (S.F.C.V, R.H.H.P, C.A.M.K)., van Lipzig MM; TNO, Zeist, The Netherlands (M.M.H.L, C.A.M.K, H.M.W, E.S); Institute for Risk Assessment Sciences, Utrecht, The Netherlands (R.H.H.P, J.A.S,); Research Centre Technology & Innovation; and Innovative Testing in Life sciences and Chemistry, University of Applied Sciences, Utrecht, The Netherlands (S.F.C.V, R.H.H.P, C.A.M.K)., Pieters RH; TNO, Zeist, The Netherlands (M.M.H.L, C.A.M.K, H.M.W, E.S); Institute for Risk Assessment Sciences, Utrecht, The Netherlands (R.H.H.P, J.A.S,); Research Centre Technology & Innovation; and Innovative Testing in Life sciences and Chemistry, University of Applied Sciences, Utrecht, The Netherlands (S.F.C.V, R.H.H.P, C.A.M.K)., Krul CA; TNO, Zeist, The Netherlands (M.M.H.L, C.A.M.K, H.M.W, E.S); Institute for Risk Assessment Sciences, Utrecht, The Netherlands (R.H.H.P, J.A.S,); Research Centre Technology & Innovation; and Innovative Testing in Life sciences and Chemistry, University of Applied Sciences, Utrecht, The Netherlands (S.F.C.V, R.H.H.P, C.A.M.K)., Wortelboer HM; TNO, Zeist, The Netherlands (M.M.H.L, C.A.M.K, H.M.W, E.S); Institute for Risk Assessment Sciences, Utrecht, The Netherlands (R.H.H.P, J.A.S,); Research Centre Technology & Innovation; and Innovative Testing in Life sciences and Chemistry, University of Applied Sciences, Utrecht, The Netherlands (S.F.C.V, R.H.H.P, C.A.M.K)., van de Steeg E; TNO, Zeist, The Netherlands (M.M.H.L, C.A.M.K, H.M.W, E.S); Institute for Risk Assessment Sciences, Utrecht, The Netherlands (R.H.H.P, J.A.S,); Research Centre Technology & Innovation; and Innovative Testing in Life sciences and Chemistry, University of Applied Sciences, Utrecht, The Netherlands (S.F.C.V, R.H.H.P, C.A.M.K) evita.vandesteeg@tno.nl.

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2017 Apr; Vol. 45 (4), pp. 353-360. Date of Electronic Publication: 2017 Feb 02.

Embracing Complexity beyond Systems Medicine: A New Approach to Chronic Immune Disorders.

Autor: Te Velde AA; Tytgat Institute for Liver and Intestinal Research, Academic Medical Center , Amsterdam , Netherlands., Bezema T; Immunowell Foundation , Utrecht , Netherlands., van Kampen AH; Bioinformatics Laboratory, Clinical Epidemiology, Biostatistics and Bioinformatics (KEBB), Academic Medical Center, Amsterdam, Netherlands; Biosystems Data Analysis, Swammerdam Institute for Life Sciences (SILS), University of Amsterdam, Amsterdam, Netherlands., Kraneveld AD; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Netherlands; Institute for Risk Assessment Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands., 't Hart BA; Department of Immunobiology, Biomedical Primate Research Centre, Rijswijk, Netherlands; Department of Immunology, Erasmus University Medical Center, Rotterdam, Netherlands; Department of Neuroscience, University Medical Center, University of Groningen, Groningen, Netherlands., van Middendorp H; Institute of Psychology, Health, Medical, and Neuropsychology Unit, Faculty of Social and Behavioural Sciences, Leiden University , Leiden , Netherlands., Hack EC; Laboratory of Translational Immunology, University Medical Center Utrecht , Utrecht , Netherlands., van Montfrans JM; Division of Pediatrics, Pediatric Immunology and Infectious Diseases, Wilhelmina Children's Hospital, University Medical Center Utrecht , Utrecht , Netherlands., Belzer C; Laboratory of Microbiology, Wageningen University , Wageningen , Netherlands., Jans-Beken L; Department of Psychology and Educational Sciences, Open University , Heerlen , Netherlands., Pieters RH; Institute for Risk Assessment Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands; Institute for Life Sciences and Chemistry, HU University of Applied Sciences Utrecht, Utrecht, Netherlands., Knipping K; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Netherlands; Immunology Platform, Nutricia Research, Utrecht, Netherlands., Huber M; Institute for Positive Health , Amersfoort , Netherlands., Boots AM; Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen , Groningen , Netherlands., Garssen J; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, Netherlands; Immunology Platform, Nutricia Research, Utrecht, Netherlands., Radstake TR; Laboratory of Translational Immunology, Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht , Utrecht , Netherlands., Evers AW; Institute of Psychology, Health, Medical, and Neuropsychology Unit, Faculty of Social and Behavioural Sciences, Leiden University , Leiden , Netherlands., Prakken BJ; Laboratory of Translational Immunology, Division of Pediatrics, Wilhelmina Children's Hospital, University Medical Center Utrecht , Utrecht , Netherlands., Joosten I; Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud University Medical Centre , Nijmegen , Netherlands.

Publikováno v: Frontiers in immunology [Front Immunol] 2016 Dec 12; Vol. 7, pp. 587. Date of Electronic Publication: 2016 Dec 12 (Print Publication: 2016).

Heterogeneous responses and cross reactivity between the major peanut allergens Ara h 1, 2,3 and 6 in a mouse model for peanut allergy.

Autor: Smit JJ; Immunotoxicology group, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands ; Utrecht Centre for Food Allergy, Utrecht, The Netherlands., Pennings MT; Utrecht Centre for Food Allergy, Utrecht, The Netherlands ; Utrecht University Medical Center, Utrecht, The Netherlands ; Current affiliation: HU University of Applied Sciences, Utrecht, The Netherlands., Willemsen K; Immunotoxicology group, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands., van Roest M; Immunotoxicology group, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands., van Hoffen E; Utrecht University Medical Center, Utrecht, The Netherlands ; Current affiliation: NIZO food research BV, Ede, The Netherlands., Pieters RH; Immunotoxicology group, Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands.

Publikováno v: Clinical and translational allergy [Clin Transl Allergy] 2015 Mar 23; Vol. 5, pp. 13. Date of Electronic Publication: 2015 Mar 23 (Print Publication: 2015).

DHA-rich tuna oil effectively suppresses allergic symptoms in mice allergic to whey or peanut.

Autor: van den Elsen LW; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science., Bol-Schoenmakers M; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands; and., van Esch BC; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science Nutricia Research, Centre for Specialised Nutrition, Utrecht, The Netherlands., Hofman GA; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science., van de Heijning BJ; Nutricia Research, Centre for Specialised Nutrition, Utrecht, The Netherlands., Pieters RH; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands; and., Smit JJ; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands; and., Garssen J; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science Nutricia Research, Centre for Specialised Nutrition, Utrecht, The Netherlands., Willemsen LE; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science l.e.m.willemsen@uu.nl.

Publikováno v: The Journal of nutrition [J Nutr] 2014 Dec; Vol. 144 (12), pp. 1970-6. Date of Electronic Publication: 2014 Oct 23.

Air pollution exposure affects circulating white blood cell counts in healthy subjects: the role of particle composition, oxidative potential and gaseous pollutants - the RAPTES project.

Autor: Steenhof M; Division of Toxicology and Division of Environmental Epidemiology, Institute for Risk Assessment Sciences (IRAS), Utrecht University , Utrecht , The Netherlands ., Janssen NA, Strak M, Hoek G, Gosens I, Mudway IS, Kelly FJ, Harrison RM, Pieters RH, Cassee FR, Brunekreef B

Publikováno v: Inhalation toxicology [Inhal Toxicol] 2014 Feb; Vol. 26 (3), pp. 141-65.