Tumor-educated Tregs drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche

Autor: Kos, Kevin, Aslam, Muhammad A., van de Ven, Rieneke, Wellenstein, Max D., Pieters, Wietske, van Weverwijk, Antoinette, Duits, Danique E.M., van Pul, Kim, Hau, Cheei-Sing, Vrijland, Kim, Kaldenbach, Daphne, Raeven, Elisabeth A.M., Quezada, Sergio A., Beyaert, Rudi, Jacobs, Heinz, de Gruijl, Tanja D., de Visser, Karin E.

Publikováno v: In Cell Reports 1 March 2022 38(9)

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Unexpected moves: a conformational change in MutSα enables high-affinity DNA mismatch binding.

Autor: Bruekner, Susanne R, Pieters, Wietske, Fish, Alexander, Liaci, A Manuel, Scheffers, Serge, Rayner, Emily, Kaldenbach, Daphne, Drost, Lisa, Dekker, Marleen, van Hees-Stuivenberg, Sandrine, Delzenne-Goette, Elly, de Konink, Charlotte, Houlleberghs, Hellen, Dubbink, Hendrikus Jan, AlSaegh, Abeer, de Wind, Niels, Förster, Friedrich, te Riele, Hein, Sixma, Titia K

Publikováno v: Nucleic Acids Research; 2/22/2023, Vol. 51 Issue 3, p1173-1188, 16p

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Insulin-like growth factor axis targeting in cancer and tumour angiogenesis – the missing link

Autor: van Beijnum, Judy R., Pieters, Wietske, Nowak-Sliwinska, Patrycja, Griffioen, Arjan W.

Publikováno v: Biological Reviews, 92(3), 1755-1768. Wiley-Blackwell
van Beijnum, J R, Pieters, W, Nowak-Sliwinska, P & Griffioen, A W 2017, ' Insulin-like growth factor axis targeting in cancer and tumour angiogenesis – the missing link ', Biological Reviews, vol. 92, no. 3, pp. 1755-1768 . https://doi.org/10.1111/brv.12306

Numerous molecular players in the process of tumour angiogenesis have been shown to offer potential for therapeutic targeting. Initially denoted to be involved in malignant transformation and tumour progression, the insulin-like growth factor (IGF) s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7262ae19aef242fc467551d59343e52d
https://research.vumc.nl/en/publications/70580c70-4993-401e-9616-f8e8baa4b8ad