Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Pieternella Slagboom"'
Autor:
Irmhild Altmann-Schneider, Anton J M de Craen, Annette A van den Berg-Huysmans, Pieternella Slagboom, Rudi G J Westendorp, Mark A van Buchem, Jeroen van der Grond
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120778 (2015)
This study aimed to investigate whether magnetization transfer imaging (MTI) parameters of cortical gray and white matter and subcortical gray matter structures differ between subjects enriched for human familial longevity and control subjects to pro
Externí odkaz:
https://doaj.org/article/33f7821ee5e042bcacd95d79ed067187
Autor:
Filippo Cademartiri, Michael Golatta, Lucie Sukupova, Yury Patrunov, Pieternella Slagboom, Sofya Morozova
Publikováno v:
Insights into Imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77217f294ec5d0a4418d8cd17661bcf
http://europepmc.org/articles/PMC3948179
http://europepmc.org/articles/PMC3948179
Autor:
Michael Preuss, Christopher Nelson, Marja-Liisa Nuotio, Peter P Pramstaller, Leo-Pekka Lyytikäinen, David Altshuler, Vilmundur Gudnason, Andrew Hicks, Andreas Ziegler, Hae-Won Uh, Zouhair Aherrahrou, Claudia Langenberg, Stavroula Kanoni, Terho Lehtimäki, Christie Ballantyne, Toby Johnson, Celia Greenwood, Cornelia Van Duijn, David Couper, Annette Peters, Pieternella Slagboom, Marian Beekman, Jeanette Erdmann, Robert Kenneth Semple, Aurelian Bidulescu, Christian Fuchsberger, Kati Kristiansson, Marcus Kleber, Tanja Zeller, Thomas Meitinger, Themistocles Assimes, Florian Kronenberg, Olle Melander, Ingrid Meulenbelt
Publikováno v:
Atherosclerosis; Vol 229
Atherosclerosis
Atherosclerosis
Objective A large body of epidemiologic data strongly suggests an association between excess adiposity and coronary artery disease (CAD). Low adiponectin levels, a hormone secreted only from adipocytes, have been associated with an increased risk of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1515e72ec20fb240c6a4456dab269756
https://doi.org/10.1016/j.atherosclerosis.2013.03.034
https://doi.org/10.1016/j.atherosclerosis.2013.03.034
Autor:
Joyce Van Meurs, Marc Jan Bonder, Oscar Franco, Eric Sijbrands, Morris Swertz, René Pool, H. Eka D. Suchiman, Cornelia Van Duijn, Jenny Van Dongen, Pieternella Slagboom, Marian Beekman, Szymon Kiełbasa, Lude Franke, Abbas Dehghan, Patrick Deelen
Publikováno v:
Diabetologia, 59(5), 998-1006
Diabetologia
Ligthart, S, Steenaard, R V, Peters, M J, van Meurs, J B J, Sijbrands, E J G, Uitterlinden, A G, Bonder, M J, Pool, R, Hofman, A, Franco, O H & Dehghan, A 2016, ' Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes ', Diabetologia, vol. 59, no. 5, pp. 998-1006 . https://doi.org/10.1007/s00125-016-3872-0
Diabetologia, 59(5), 998-1006. Springer-Verlag
Diabetologia, 59(5), 998-1006. Springer Verlag
BIOS Consortium 2016, ' Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes ', Diabetologia, vol. 59, no. 5, pp. 998-1006 . https://doi.org/10.1007/s00125-016-3872-0
Diabetologia, 59(5), 998-1006. SPRINGER
Diabetologia
Ligthart, S, Steenaard, R V, Peters, M J, van Meurs, J B J, Sijbrands, E J G, Uitterlinden, A G, Bonder, M J, Pool, R, Hofman, A, Franco, O H & Dehghan, A 2016, ' Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes ', Diabetologia, vol. 59, no. 5, pp. 998-1006 . https://doi.org/10.1007/s00125-016-3872-0
Diabetologia, 59(5), 998-1006. Springer-Verlag
Diabetologia, 59(5), 998-1006. Springer Verlag
BIOS Consortium 2016, ' Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes ', Diabetologia, vol. 59, no. 5, pp. 998-1006 . https://doi.org/10.1007/s00125-016-3872-0
Diabetologia, 59(5), 998-1006. SPRINGER
Aims/hypothesis Tobacco smoking, a risk factor for diabetes, is an established modifier of DNA methylation. We hypothesised that tobacco smoking modifies DNA methylation of genes previously identified for diabetes. Methods We annotated CpG sites avai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1780ca7fddc8ae892d332f55385529
https://doi.org/10.1007/s00125-016-3872-0
https://doi.org/10.1007/s00125-016-3872-0
Autor:
Joyce Van Meurs, Marc Jan Bonder, Marleen Van Greevenbroek, Michel Nivard, Morris Swertz, René Pool, H. Eka D. Suchiman, Coen Stehouwer, Marijn Verkerk, Cornelia Van Duijn, Jenny Van Dongen, Pieternella Slagboom, Marian Beekman, Casper G Schalkwijk, Szymon Kiełbasa, Lude Franke, Rick Jansen, Gonneke Willemsen, Carla Van der Kallen, Patrick Deelen
Publikováno v:
Nature Communications
Nature Communications, 7:11115. Nature Publishing Group
Nature Communications, 7. Nature Publishing Group
van Dongen, J, Nivard, M G, Willemsen, G, Hottenga, J-J, Helmer, Q, Dolan, C V, Ehli, E A, Davies, G E, van Iterson, M, Breeze, C E, Beck, S, Suchiman, H E, Jansen, R, van Meurs, J B, Heijmans, B T, Slagboom, P E & Boomsma, D I 2016, ' Genetic and environmental influences interact with age and sex in shaping the human methylome ', Nature Communications, vol. 7 . https://doi.org/10.1038/ncomms11115
Nature Communications, 7(11115):11115, 1-13. Nature Publishing Group
Nature Communications, 7
van Dongen, J, Nivard, M G, Willemsen, G, Hottenga, J J, Helmer, Q, Dolan, C V, Ehli, E A, Davies, G E, van Iterson, M, Breeze, C E, Beck, S, Pool, R, Suchiman, H E D, Jansen, R, van Meurs, J B, Heijmans, B T, Slagboom, P E & Boomsma, D I 2016, ' Genetic and environmental influences interact with age and sex in shaping the human methylome ', Nature Communications, vol. 7, no. 11115, 11115, pp. 1-13 . https://doi.org/10.1038/ncomms11115
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications, 7:11115. Nature Publishing Group
Nature Communications, 7. Nature Publishing Group
van Dongen, J, Nivard, M G, Willemsen, G, Hottenga, J-J, Helmer, Q, Dolan, C V, Ehli, E A, Davies, G E, van Iterson, M, Breeze, C E, Beck, S, Suchiman, H E, Jansen, R, van Meurs, J B, Heijmans, B T, Slagboom, P E & Boomsma, D I 2016, ' Genetic and environmental influences interact with age and sex in shaping the human methylome ', Nature Communications, vol. 7 . https://doi.org/10.1038/ncomms11115
Nature Communications, 7(11115):11115, 1-13. Nature Publishing Group
Nature Communications, 7
van Dongen, J, Nivard, M G, Willemsen, G, Hottenga, J J, Helmer, Q, Dolan, C V, Ehli, E A, Davies, G E, van Iterson, M, Breeze, C E, Beck, S, Pool, R, Suchiman, H E D, Jansen, R, van Meurs, J B, Heijmans, B T, Slagboom, P E & Boomsma, D I 2016, ' Genetic and environmental influences interact with age and sex in shaping the human methylome ', Nature Communications, vol. 7, no. 11115, 11115, pp. 1-13 . https://doi.org/10.1038/ncomms11115
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
The methylome is subject to genetic and environmental effects. Their impact may depend on sex and age, resulting in sex- and age-related physiological variation and disease susceptibility. Here we estimate the total heritability of DNA methylation le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7985cca2e2423e67a6b4593a7a0b7364
http://europepmc.org/articles/PMC4820961
http://europepmc.org/articles/PMC4820961
Autor:
Alexandros Kanterakis, Bruce H.R. Wolffenbuttel, Morris Swertz, Sara Pulit, H. Eka D. Suchiman, Cornelia Van Duijn, Pieternella Slagboom, Marian Beekman, Barbera Van Schaik, Lennart C. Karssen, Esther Van Enckevort, Alexander Schönhuth, Patrick Deelen
Publikováno v:
Nature Protocols, 10(9), 1285. Nature Publishing Group
Nature protocols, 10(9), 1285-1296. Nature Publishing Group
Nature Protocols, 10(9), 1285-1296. Nature Publishing Group
Nature Protocols, 10(9), 1285-1296
van Leeuwen, E M, Kanterakis, A, Deelen, P, Kattenberg, V M, Slagboom, P E, Bakker, P I W, Wijmenga, C, Swertz, M A, Boomsma, D I, van Duijn, C M, Karssen, L C & Hottenga, J J 2015, ' Population-specific genotype imputations using minimac or IMPUTE2 ', Nature Protocols, vol. 10, no. 9, pp. 1285-1296 . https://doi.org/10.1038/nprot.2015.077
Nature Protocols, 10, 1285-1296
Nature protocols, 10(9), 1285-1296. Nature Publishing Group
Nature Protocols, 10(9), 1285-1296. Nature Publishing Group
Nature Protocols, 10(9), 1285-1296
van Leeuwen, E M, Kanterakis, A, Deelen, P, Kattenberg, V M, Slagboom, P E, Bakker, P I W, Wijmenga, C, Swertz, M A, Boomsma, D I, van Duijn, C M, Karssen, L C & Hottenga, J J 2015, ' Population-specific genotype imputations using minimac or IMPUTE2 ', Nature Protocols, vol. 10, no. 9, pp. 1285-1296 . https://doi.org/10.1038/nprot.2015.077
Nature Protocols, 10, 1285-1296
In order to meaningfully analyze common and rare genetic variants, results from genome-wide association studies (GWASASs) of multiple cohorts need to be combined in a meta-analysis in order to obtain enough power. This requires all cohorts to have th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb56ff36564ca339a625fc26e137ad19
https://dspace.library.uu.nl/handle/1874/333152
https://dspace.library.uu.nl/handle/1874/333152
Autor:
Filippo Cademartiri, Michael Golatta, Stephanie Withey, Lucie Sukupova, Yury Patrunov, Pieternella Slagboom, Sofya Morozova, Jan Van Zelst
Publikováno v:
Insights into Imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036d1890d1afe2e173984e3a80e7bca0
https://pubmed.ncbi.nlm.nih.gov/24573562
https://pubmed.ncbi.nlm.nih.gov/24573562
Autor:
Nicholas Schork, Eleftheria Zeggini, Elena Tenconi, Cynthia Bulik, Raquel Rabionet, Xavier Estivill, Julia Huemer, Pieternella Slagboom, FERNANDO FERNANDEZ-ARANDA, Stephanie Le Hellard, Marion Roberts, Andrew Bergen, Federica Tozzi, André Scherag, Cinnamon Bloss, Pamela Keel
Publikováno v:
Molecular psychiatry. 16(9)
Anorexia nervosa (AN) is a mental illness with high mortality that most commonly afflicts adolescent female individuals. Clinical symptoms include chronic food refusal, weight loss and body image distortions. We carried out a genome-wide association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3d0dfea9e363baf8d3f1fcb3105cda
https://pubmed.ncbi.nlm.nih.gov/21079607
https://pubmed.ncbi.nlm.nih.gov/21079607