Zobrazeno 1 - 10
of 602
pro vyhledávání: '"Pieter. S. Hiemstra"'
Publikováno v:
European Respiratory Review, Vol 15, Iss 101, Pp 182-184 (2006)
Inflammatory cells that infiltrate and surround the airway smooth muscle (ASM) layer express antimicrobial peptides including the cathelicidin LL-37. LL-37 has been shown to activate epithelial cells by transactivation of the epidermal growth factor
Externí odkaz:
https://doaj.org/article/f5bcf7ac53884ad5aacc8d1df138d512
Autor:
Judith van Paassen, Pieter S. Hiemstra, Abraham C. van der Linden, Evert de Jonge, Jaap Jan Zwaginga, Robert J.M. Klautz, M. Sesmu Arbous
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-4 (2024)
Abstract Heart surgery may be complicated by acute lung injury and adult respiratory distress syndrome. Expression and release of mucins MUC5AC and MUC5B in the lungs has been reported to be increased in acute lung injury. The aim of our study was to
Externí odkaz:
https://doaj.org/article/85a5a2d329db427ebf1adc34251dbe84
Autor:
Li Jia, Na Li, Vincent van Unen, Jaap-Jan Zwaginga, Jerry Braun, Pieter S. Hiemstra, Frits Koning, P. Padmini S. J. Khedoe, Jan Stolk
Publikováno v:
Cells, Vol 13, Iss 19, p 1636 (2024)
Emphysema in patients with chronic obstructive pulmonary disease (COPD) is characterized by progressive inflammation. Preclinical studies suggest that lung volume reduction surgery (LVRS) and mesenchymal stromal cell (MSC) treatment dampen inflammati
Externí odkaz:
https://doaj.org/article/3b7d1e31afbb46d1b586ba30900fd01f
Autor:
Ilonka. H. van Veen, Pieter. S. Hiemstra, Anneke ten Brinke, Anja Roos, Renate. M. Verhoosel, Jaap. K. Sont, Peter. J. Sterk, Klaus. F. Rabe, Elisabeth. H. Bel
Publikováno v:
European Respiratory Review, Vol 15, Iss 101, Pp 224-225 (2006)
There is increasing evidence that activation of the complement system in asthma contributes to ongoing inflammation, tissue damage and airway remodeling. Mannose binding lectin (MBL) is a pattern recognition molecule that serves as the key mediator o
Externí odkaz:
https://doaj.org/article/0b7b82d3d26149f0aabe9a5c3cf1360e
Autor:
Ying Wang, Dennis K. Ninaber, Alen Faiz, Abraham C. van der Linden, Annemarie van Schadewijk, René Lutter, Pieter S. Hiemstra, Anne M. van der Does, Abilash Ravi
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background Acute exacerbations of chronic inflammatory lung diseases, such as chronic obstructive pulmonary disease (COPD), are frequently associated with rhinovirus (RV) infections. Despite these associations, the pathogenesis of virus-indu
Externí odkaz:
https://doaj.org/article/0f718170c5814a07a68d573420f11365
Autor:
Simon D. Pouwels, Maarten van den Berge, Gwenda F. Vasse, Wim Timens, Corry-Anke Brandsma, Hananeh Aliee, Pieter S. Hiemstra, Victor Guryev, Alen Faiz
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-4 (2023)
Abstract After more than two years the COVID-19 pandemic, that is caused by infection with the respiratory SARS-CoV-2 virus, is still ongoing. The risk to develop severe COVID-19 upon SARS-CoV-2 infection is increased in individuals with a high age,
Externí odkaz:
https://doaj.org/article/a6f45db6b6ff4fa783aeb8895d83f2c5
Autor:
Ying Wang, Melissa Thaler, Clarisse Salgado‐Benvindo, Nathan Ly, Anouk A Leijs, Dennis K Ninaber, Philip M Hansbro, Fia Boedijono, Martijn J vanHemert, Pieter S Hiemstra, Anne M van derDoes, Alen Faiz
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 4, Pp n/a-n/a (2024)
Abstract Objectives Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a member of a class of highly pathogenic coronaviruses. The large family of coronaviruses, however, also includes members that cause only mild symptoms, like huma
Externí odkaz:
https://doaj.org/article/96373f7e3aa545fa9caaace0f161e570
Autor:
Anthony Altieri, Hadeesha Piyadasa, Mahadevappa Hemshekhar, Natasha Osawa, Breann Recksiedler, Victor Spicer, Pieter S Hiemstra, Andrew J Halayko, Neeloffer Mookherjee
Publikováno v:
Journal of Inflammation, Vol 19, Iss 1, Pp 1-19 (2022)
Abstract Background The heterodimer interleukin (IL)-17A/F is elevated in the lungs in chronic respiratory disease such as severe asthma, along with the pro-inflammatory cytokine tumor necrosis factor-α (TNF-α). Although IL-17A/F and TNF-α are kno
Externí odkaz:
https://doaj.org/article/c8b489cd99bd4d6aa28addd427a91816
Autor:
Amy M. Barclay, Dennis K. Ninaber, Suzanne van Veen, Pieter S. Hiemstra, Tom H. M. Ottenhoff, Anne M. van der Does, Simone A. Joosten
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Lung epithelial cells represent the first line of host defence against foreign inhaled components, including respiratory pathogens. Their responses to these exposures may direct subsequent immune activation to these pathogens. The epithelial response
Externí odkaz:
https://doaj.org/article/a0876ddedddc4b0693e33b951e2551ea
Autor:
Janna C. Nawroth, Doris Roth, Annemarie van Schadewijk, Abilash Ravi, Tengku Ibrahim Maulana, Christiana N. Senger, Sander van Riet, Dennis K. Ninaber, Amy M. de Waal, Dorothea Kraft, Pieter S. Hiemstra, Amy L. Ryan, Anne M. van der Does
Publikováno v:
Materials Today Bio, Vol 21, Iss , Pp 100713- (2023)
Human lung function is intricately linked to blood flow and breathing cycles, but it remains unknown how these dynamic cues shape human airway epithelial biology. Here we report a state-of-the-art protocol for studying the effects of dynamic medium a
Externí odkaz:
https://doaj.org/article/b465a49779b14df2bc3adc7415557aaf