Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Pieter Van Brantegem"'
Autor:
Lorenz Van der Linden, Julie Hias, Astrid Liesenborghs, Karolien Walgraeve, Pieter Van Brantegem, Laura Hellemans, Koen Milisen, Jos Tournoy
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Chronic use of hypnotic agents is prevalent in older adults, who as a result are at increased risk for certain adverse events, such as day-time drowsiness and falls. Multiple strategies to discontinue hypnotics have been tested in
Externí odkaz:
https://doaj.org/article/d9330b3ce7644bdabef8a5e02ebfd79b
Autor:
Felix R. De Bie, Francesca M. Russo, Pieter Van Brantegem, Barbara E. Coons, James K. Moon, Zexuan Yang, Chengcheng Pang, Janaina C. Senra, Camilla Omann, Pieter Annaert, Karel Allegaert, Marcus G. Davey, Alan W. Flake, Jan Deprest
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 143, Iss , Pp 112161- (2021)
Background: Maternal transplacental administration of sildenafil is being considered for a variety of fetal conditions. Clinical translation also requires evaluation of fetal safety in a higher species, such as the fetal lamb. Experiments with the pr
Externí odkaz:
https://doaj.org/article/a5d5db197a884d12bc8d9ee5680753b9
Publikováno v:
MethodsX, Vol 7, Iss , Pp 101080- (2020)
Drug-induced cholestasis (DIC) is a major cause of clinical failure of drug candidates. Numerous patients worldwide are affected when exposed to marketed drugs exhibiting a DIC signature. Prospective identification of DIC during early compound develo
Externí odkaz:
https://doaj.org/article/45e1a141547342b3bc34d63d0fb12417
Autor:
Ruth Van Daele, Joost Wauters, Pieter De Cock, Franky Buyle, John Leys, Pieter Van Brantegem, Matthias Gijsen, Pieter Annaert, Yves Debaveye, Katrien Lagrou, Willy E. Peetermans, Roger J. Brüggemann, Isabel Spriet
Publikováno v:
Antibiotics, Vol 10, Iss 9, p 1112 (2021)
Background: Voriconazole is an antifungal drug used as one of the first-line treatments for invasive aspergillosis. This drug is extensively metabolized, predominantly via cytochrome P450 enzymes. An interaction between flucloxacillin and voriconazol
Externí odkaz:
https://doaj.org/article/d518ce7c695b4b679e9787766d2dad50
Autor:
Axelle Cooreman, Raf Van Campenhout, Sara Crespo Yanguas, Eva Gijbels, Kaat Leroy, Alanah Pieters, Andrés Tabernilla, Pieter Van Brantegem, Pieter Annaert, Bruno Cogliati, Mathieu Vinken
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6534 (2020)
Connexins are goal keepers of tissue homeostasis, including in the liver. As a result, they are frequently involved in disease. The current study was set up to investigate the effects of cholestatic disease on the production of connexin26, connexin32
Externí odkaz:
https://doaj.org/article/033a81fe174e47309097ba3fa8e700e9
Autor:
Bing Qi, Matthias Gijsen, Tom De Vocht, Neel Deferm, Pieter Van Brantegem, Getahun B. Abza, Nina Nauwelaerts, Joost Wauters, Isabel Spriet, Pieter Annaert
Publikováno v:
Pharmaceutical Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2455d0708b349aad7537237b33b9256
https://doi.org/10.1007/s11095-023-03536-7
https://doi.org/10.1007/s11095-023-03536-7
Autor:
Lorenz Roger Van der Linden, Julie Hias, Astrid Liesenborghs, Karolien Walgraeve, Pieter Van Brantegem, Laura Hellemans, Koen Milisen, Jos Tournoy
Background Chronic use of hypnotic agents is prevalent in older adults, who as a result are at increased risk for certain adverse events, such as day-time drowsiness and falls. Multiple strategies to discontinue hypnotics have been tested in geriatri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba0e57c210675043c29ce7fc76d39413
https://doi.org/10.21203/rs.3.rs-2012686/v1
https://doi.org/10.21203/rs.3.rs-2012686/v1
Autor:
Isabel Spriet, Pieter Van Brantegem, Bing Qi, Tom De Vocht, Nina Nauwelaerts, Pieter Annaert, Joost Wauters, Matthias Gijsen, Getahun B. Abza, Neel Deferm
Publikováno v:
Drug Testing and Analysis. 12:1183-1195
Colistin (polymyxin E) is a polycation antibiotic which is increasingly used (administered as colistin methanesulfonate, CMS) as a salvage therapy in critically ill patients with multidrug resistant Gram-negative infections. Even though colistin has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac5032af4cc83a28e4113fb99ff0753
https://doi.org/10.1002/dta.2812
https://doi.org/10.1002/dta.2812
A sensitive liquid chromatography method for analysis of propofol in small volumes of neonatal blood
Autor:
Johan Nicolaï, Pieter Annaert, Pieter Van Brantegem, Karel Allegaert, Anne Smits, Tom De Vocht, Neel Deferm, Bing Qi
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics, 45(1), 128-133. Wiley-Blackwell Publishing Ltd
WHAT IS KNOWN AND OBJECTIVE: Sampling volumes of blood from neonates is necessarily limited. However, most of the published propofol analysis assays require a relatively large blood sample volume (typically ≥0.5 mL). Therefore, the aim of the prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce7d35caa112c714bacd5294ccd06c4
https://doi.org/10.1111/jcpt.13038
https://doi.org/10.1111/jcpt.13038
Autor:
Mathieu Vinken, Pieter Annaert, Sagnik Chatterjee, Axelle Cooreman, Lysiane Richert, Pieter Van Brantegem, Erwin Dreesen, Neel Deferm, Marlies Oorts
Bosentan, a well–known cholestatic agent, was not identified as cholestatic at concentrations up to 200 µM based on the drug-induced cholestasis (DIC) index value, determined in a sandwich-cultured human hepatocyte (SCHH)–based DIC assay. To obt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c217992b234cbd7bc6a7d4f08e3d953b
https://hdl.handle.net/20.500.14017/e05ae3dd-cdd5-4a09-8f8a-4cf98ecbca80
https://hdl.handle.net/20.500.14017/e05ae3dd-cdd5-4a09-8f8a-4cf98ecbca80