Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Pieter Vader"'
Autor:
Vivian V. T. Nguyen, Joshua A. Welsh, Tobias Tertel, Andre Choo, Simonides I. van deWakker, Kyra A. Y. Defourny, Bernd Giebel, Pieter Vader, Jayanthi Padmanabhan, Sai Kiang Lim, Esther N. M. Nolte‐'t Hoen, Marianne C. Verhaar, R. Beklem Bostancioglu, Antje M. Zickler, Jia Mei Hong, Jennifer C. Jones, Samir EL Andaloussi, Bas W. M. vanBalkom, André Görgens
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 6, Pp n/a-n/a (2024)
Abstract Mesenchymal stromal cells (MSCs) are promising regenerative therapeutics that primarily exert their effects through secreted extracellular vesicles (EVs). These EVs – being small and non‐living – are easier to handle and possess advant
Externí odkaz:
https://doaj.org/article/ae35180078c5434b854c0344b3d59bb2
Autor:
Scott E. Bonner, Simonides I. van deWakker, William Phillips, Eduard Willms, Joost P. G. Sluijter, Andrew F. Hill, Matthew J. A. Wood, Pieter Vader
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 2, Pp n/a-n/a (2024)
Abstract Extracellular vesicles (EVs) are cell derived membranous nanoparticles. EVs are important mediators of cell–cell communication via the transfer of bioactive content and as such they are being investigated for disease diagnostics as biomark
Externí odkaz:
https://doaj.org/article/add20762f9074cf6b277f96e8773807b
Autor:
Simonides Immanuel van deWakker, Julia Bauzá‐Martinez, Carla Ríos Arceo, Herak Manjikian, Christian Jamie Bernard Snijders Blok, Marieke Theodora Roefs, Eduard Willms, Renee Goverdina Catharina Maas, Matti Feije Pronker, Olivier Gerrit deJong, Wei Wu, André Görgens, Samir El Andaloussi, Joost Petrus Gerardus Sluijter, Pieter Vader
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 1, Pp n/a-n/a (2024)
Abstract Cardiac progenitor cell (CPC)‐derived small extracellular vesicles (sEVs) exhibit great potential to stimulate cardiac repair. However, the multifaceted nature of sEV heterogeneity presents a challenge in understanding the distinct mechani
Externí odkaz:
https://doaj.org/article/216f54e574094a04966cba7e541ce4bb
Autor:
Nazma F. Ilahibaks, Thomas A. Kluiver, Olivier G. deJong, Saskia C. A. deJager, Raymond M. Schiffelers, Pieter Vader, Weng Chuan Peng, Zhiyong Lei, Joost P. G. Sluijter
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 1, Pp n/a-n/a (2024)
Abstract The loss‐of‐function of the proprotein convertase subtilisin–kexin type 9 (Pcsk9) gene has been associated with significant reductions in plasma serum low‐density lipoprotein cholesterol (LDL‐C) levels. Both CRISPR/Cas9 and CRISPR
Externí odkaz:
https://doaj.org/article/83cebf0ddaa745919861e6dd47a10bfc
Autor:
Thomas S. van Solinge, Kristina Pagh Friis, Killian O'Brien, Romy L. Verschoor, Jeroen van Aarle, Arnold Koekman, Xandra O. Breakefield, Pieter Vader, Raymond Schiffelers, Marike Broekman
Publikováno v:
International Journal of Pharmaceutics: X, Vol 6, Iss , Pp 100191- (2023)
In glioblastoma, a malignant primary brain tumor, liposomes have shown promise in pre-clinical and early phase clinical trials as delivery vehicles for therapeutics. However, external factors influencing cellular uptake of liposomes in glioma cells a
Externí odkaz:
https://doaj.org/article/bc7247982f4e45ef838e816f85d2dbd5
Autor:
Marieke Theodora Roefs, Julia Bauzá-Martinez, Simonides Immanuel van de Wakker, Jiabin Qin, Willem Theodoor Olijve, Robin Tuinte, Marjolein Rozeboom, Christian Snijders Blok, Emma Alise Mol, Wei Wu, Pieter Vader, Joost Petrus Gerardus Sluijter
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Extracellular vesicles (EVs) are cell-derived lipid bilayer-enclosed particles that play a role in intercellular communication. Cardiac progenitor cell (CPC)-derived EVs have been shown to protect the myocardium against ischemia-reperfusion
Externí odkaz:
https://doaj.org/article/27db586875664b9cb4dbdeb36d2d3c0f
Autor:
Maria Laura Tognoli, Julia Dancourt, Emeline Bonsergent, Roberta Palmulli, Olivier G. de Jong, Guillaume Van Niel, Eric Rubinstein, Pieter Vader, Gregory Lavieu
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-9 (2023)
Abstract Extracellular vesicles (EVs) are thought to mediate intercellular communication by transferring cargoes from donor to acceptor cells. The EV content-delivery process within acceptor cells is still poorly characterized and debated. CD63 and C
Externí odkaz:
https://doaj.org/article/9a7af7b0c0134002886bc31fa5e6f3d6
Autor:
Nazma F. Ilahibaks, Marieke T. Roefs, Maike A. D. Brans, Christian Snijders Blok, Saskia C. A. deJager, Raymond M. Schiffelers, Pieter Vader, Zhiyong Lei, Joost P. G. Sluijter
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 9, Pp n/a-n/a (2023)
Abstract Extracellular vesicles (EVs) are nanoscale particles that facilitate intercellular communication. They are regarded as a promising natural drug delivery system for transporting and delivering bioactive macromolecules to target cells. Recentl
Externí odkaz:
https://doaj.org/article/f0d6509b52744eafa22ce31a72ced2f4
Autor:
Laurens Raes, Melissa Pille, Aranit Harizaj, Glenn Goetgeluk, Jelter Van Hoeck, Stephan Stremersch, Juan C. Fraire, Toon Brans, Olivier Gerrit de Jong, Roel Maas-Bakker, Enrico Mastrobattista, Pieter Vader, Stefaan C. De Smedt, Bart Vandekerckhove, Koen Raemdonck, Kevin Braeckmans
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 696-707 (2021)
The CRISPR-Cas9 technology represents a powerful tool for genome engineering in eukaryotic cells, advancing both fundamental research and therapeutic strategies. Despite the enormous potential of the technology, efficient and direct intracellular del
Externí odkaz:
https://doaj.org/article/d83a80530b204562bf8701e1aa7bfddd
Autor:
Marieke T. Roefs, Wolf Heusermann, Maike A. D. Brans, Christian Snijders Blok, Zhiyong Lei, Pieter Vader, Joost P. G. Sluijter
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cardiac progenitor cell-derived extracellular vesicles (CPC-EVs) have been successfully applied via different delivery routes for treating post-myocardial infarction injury in several preclinical models. Hence, understanding the in vivo fate of CPC-E
Externí odkaz:
https://doaj.org/article/c30c5196cdb4453789c74e97f785554a