Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Pieter Rottiers"'
Autor:
Dana P. Cook, João Paulo Monteiro Carvalho Mori Cunha, Pieter-Jan Martens, Gabriele Sassi, Francesca Mancarella, Giuliana Ventriglia, Guido Sebastiani, An-Sofie Vanherwegen, Mark A. Atkinson, Karolien Van Huynegem, Lothar Steidler, Silvia Caluwaerts, Pieter Rottiers, Luc Teyton, Francesco Dotta, Conny Gysemans, Chantal Mathieu
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
A combination treatment (CT) of proinsulin and IL-10 orally delivered via genetically modified Lactococcus lactis bacteria combined with low-dose anti-CD3 (aCD3) therapy successfully restores glucose homeostasis in newly diagnosed non-obese diabetic
Externí odkaz:
https://doaj.org/article/fac9a292158844b7b13abb31bbfc503b
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 1, Iss 6, Pp 557-567 (1999)
In addition to eugenetic changes, cancerous cells exhibit extensive modifications in the expression levels of a variety of genes. The phenotypic switch observed after inoculation of T lymphoma cells into syngenic mice illustrates the active participa
Externí odkaz:
https://doaj.org/article/497722b7cee4442faa8d12894f209704
Autor:
Chantal Mathieu, Pieter Rottiers, Teyton L, Sassi G, Martens P-J, Laureys J, Viaene M, Conny Gysemans
Publikováno v:
Endocrine Abstracts.
Autor:
Karolien Van Huynegem, Luc Teyton, Guido Sebastiani, Gabriele Sassi, Chantal Mathieu, Giuliana Ventriglia, Lothar Steidler, Francesco Dotta, Francesca Mancarella, João Paulo Monteiro Carvalho Mori da Cunha, Silvia Caluwaerts, Mark A. Atkinson, Pieter-Jan Martens, Pieter Rottiers, Conny Gysemans, Dana P Cook, An-Sofie Vanherwegen
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
A combination treatment (CT) of proinsulin and IL-10 orally delivered via genetically modified Lactococcus lactis bacteria combined with low-dose anti-CD3 (aCD3) therapy successfully restores glucose homeostasis in newly diagnosed non-obese diabetic
Autor:
Lothar Steidler, Francesca Mancarella, Dana P Cook, Tatiana Takiishi, João Paulo Monteiro Carvalho Mori da Cunha, Clive Wasserfall, Guido Sebastiani, Conny Gysemans, Chantal Mathieu, Francesco Dotta, Hannelie Korf, Noelia Casares, Pieter Rottiers, Juan José Lasarte
The introduction of β-cell autoantigens via the gut through Lactococcus lactis (L. lactis) has been demonstrated to be a promising approach for diabetes reversal in NOD mice. Here we show that a combination therapy of low-dose anti-CD3 with a clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82acd5d2d5fed56ef675f1e0345cfb88
https://lirias.kuleuven.be/handle/123456789/570096
https://lirias.kuleuven.be/handle/123456789/570096
Publikováno v:
Annals of the New York Academy of Sciences. 1182:135-145
Interleukin-10 (IL-10) is central in immune downregulation, but so far its use in inflammatory diseases remains cumbersome. For treatment of inflammatory bowel disease, adequate amounts of IL-10 must reach the intestinal lining. Systemic injection of
Autor:
Joseph A. Murray, Eric V. Marietta, Sander J. H. van Deventer, IL Huibregtse, Frits Koning, Pieter Rottiers, Chella S. David, Shadi Rashtak
Publikováno v:
Journal of immunology (Baltimore, Md., 183(4), 2390-2396. American Association of Immunologists
Active delivery of recombinant autoantigens or allergens at the intestinal mucosa by genetically modified Lactococcus lactis (LL) provides a novel therapeutic approach for the induction of tolerance. Celiac disease is associated with either HLA-DQ2-
Autor:
Isabelle Salmon, Nathalie Nagy, Klaas Vandenbroucke, Anne Mathieu, Christine Decaestecker, Pieter Rottiers, Liesbeth Ferdinande, Claude Cuvelier, Pieter Demetter
Publikováno v:
International Journal of Experimental Pathology. 89:438-446
Galectins are increasingly the focus of biomedical research. Although they are involved at different stages in inflammation, data on galectins in colitis remain scarce. The aim of this study was to determine and compare the expression of galectins in
Autor:
Pieter Rottiers, Jasmien Taildeman, M. De Vos, Anouk Waeytens, Pieter Demetter, Claudina Perez-Novo, Liesbeth Ferdinande, C.A. Cuvelier, Isabelle Rottiers
Publikováno v:
International Journal of Immunopathology and Pharmacology. 21:289-295
Indoleamine 2,3-dioxygenase (IDO) catalyzes the first step in the degradation of tryptophan, an essential amino acid. During inflammation IDO can be induced in different cell types resulting in local tryptophan depletion. This inhibits T cell prolife
Autor:
Anouk Waeytens, Sabine Neirynck, Lothar Steidler, Martine De Vos, Pieter Rottiers, Liesbeth Ferdinande, Claude Cuvelier
Publikováno v:
Inflammatory Bowel Diseases. 14:471-479
Background: Genetically modified Lactococcus lactis secreting interleukin-10 (IL-10) has been demonstrated to provide localized delivery of a therapeutic agent through active in situ synthesis in murine colitis. At present, many aspects of the exact