Zobrazeno 1 - 10
of 294
pro vyhledávání: '"Pieter Mestdagh"'
Autor:
Cláudio Pinheiro, Niké Guilbert, Lien Lippens, Quentin Roux, Robin Boiy, Suzanne Fischer, Sofie Van Dorpe, Bram De Craene, Geert Berx, Tom Boterberg, Gwen Sys, Hannelore Denys, Ilkka Miinalainen, Pieter Mestdagh, Jo Vandesompele, Olivier De Wever, An Hendrix
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 4, Pp n/a-n/a (2024)
Abstract Extracellular vesicles (EVs) contain a plethora of biomolecules, including nucleic acids, with diverse diagnostic and therapeutic application potential. Although reverse transcription‐quantitative PCR (RT‐qPCR) is the most widely applied
Externí odkaz:
https://doaj.org/article/5495443dd1164b7f83e192f541975d2c
Autor:
Francisco Avila Cobos, Mohammad Javad Najaf Panah, Jessica Epps, Xiaochen Long, Tsz-Kwong Man, Hua-Sheng Chiu, Elad Chomsky, Evgeny Kiner, Michael J. Krueger, Diego di Bernardo, Luis Voloch, Jan Molenaar, Sander R. van Hooff, Frank Westermann, Selina Jansky, Michele L. Redell, Pieter Mestdagh, Pavel Sumazin
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-22 (2023)
Abstract Background RNA profiling technologies at single-cell resolutions, including single-cell and single-nuclei RNA sequencing (scRNA-seq and snRNA-seq, scnRNA-seq for short), can help characterize the composition of tissues and reveal cells that
Externí odkaz:
https://doaj.org/article/d4626884e3864b748b5d6fb020d26428
Autor:
Celine Everaert, Jasper Verwilt, Kimberly Verniers, Niels Vandamme, Alvaro Marcos Rubio, Jo Vandesompele, Pieter Mestdagh
Publikováno v:
Biological Procedures Online, Vol 25, Iss 1, Pp 1-19 (2023)
Abstract Background RNA sequencing has become the gold standard for transcriptome analysis but has an inherent limitation of challenging quantification of low-abundant transcripts. In contrast to microarray technology, RNA sequencing reads are propor
Externí odkaz:
https://doaj.org/article/72d160ee571d4042a249a3fb72af33c7
Autor:
Arne Vanhie, Ellen Caron, Eveline Vermeersch, Dorien O, Carla Tomassetti, Christel Meuleman, Pieter Mestdagh, Thomas M. D’Hooghe
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 888 (2024)
The aim of this systematic review is to assess the power of circulating miRNAs as biomarkers as a diagnostic tool in endometriosis. In endometriosis-suspected women with uncertain imaging, the only way to confirm or exclude endometriosis with certain
Externí odkaz:
https://doaj.org/article/27647a2972ff45aca24e5ed97ed95285
Autor:
Fien Gysens, Lisa Ostyn, Ellen Goeteyn, Eva Blondeel, Justine Nuyttens, Olivier De Wever, Eric de Bony, Aurélie Crabbé, Pieter Mestdagh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract In vitro cell culture experiments are widely used to study cellular behavior in most biological research fields. Except for suspension cells, most human cell types are cultured as adherent monolayers on a plastic surface. While technically c
Externí odkaz:
https://doaj.org/article/4dc19f017dc749a4983a18249c8d1f0e
Autor:
Merel Jacobs, Sven Verschraegen, Bihiyga Salhi, Jasper Anckaert, Pieter Mestdagh, Guy G. Brusselle, Ken R. Bracke
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Two opposing B cell subsets have been defined based on their cytokine profile: IL-6 producing effector B cells (B-effs) versus IL-10 producing regulatory B cells (B-regs) that respectively positively or negatively regulate immune
Externí odkaz:
https://doaj.org/article/e5511e46df9c4e738dbb18cf17b5f802
Autor:
Bert Dhondt, Cláudio Pinheiro, Edward Geeurickx, Joeri Tulkens, Glenn Vergauwen, Edwin Van Der Pol, Rienk Nieuwland, Anneleen Decock, Ilkka Miinalainen, Pekka Rappu, Gary Schroth, Scott Kuersten, Jo Vandesompele, Pieter Mestdagh, Nicolaas Lumen, Olivier De Wever, An Hendrix
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 5, Pp n/a-n/a (2023)
Abstract The analysis of extracellular vesicles (EV) in blood samples is under intense investigation and holds the potential to deliver clinically meaningful biomarkers for health and disease. Technical variation must be minimized to confidently asse
Externí odkaz:
https://doaj.org/article/88cf6c37fc744c8b910af6ec08d4058f
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract To increase the throughput, lower the cost, and save scarce test reagents, laboratories can pool patient samples before SARS-CoV-2 RT-qPCR testing. While different sample pooling methods have been proposed and effectively implemented in some
Externí odkaz:
https://doaj.org/article/c363eea6eff446b8a403c2a30d2cf9d7
Autor:
Eva Hulstaert, Keren Levanon, Annelien Morlion, Stefan Van Aelst, Anthony-Alexander Christidis, Ruben Zamar, Jasper Anckaert, Kimberly Verniers, Keren Bahar-Shany, Stav Sapoznik, Jo Vandesompele, Pieter Mestdagh
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 24, Iss 2, Pp 155-164 (2022)
Background: Most ovarian cancer patients are diagnosed at an advanced stage and have a high mortality rate. Current screening strategies fail to improve prognosis because markers that are sensitive for early stage disease are lacking. This medical ne
Externí odkaz:
https://doaj.org/article/1167a7ed4eff480293361fff2bcb29f0
Autor:
Louis Delhaye, Edith De Bruycker, Pieter-Jan Volders, Daria Fijalkowska, Delphine De Sutter, Sven Degroeve, Lennart Martens, Pieter Mestdagh, Sven Eyckerman
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Accumulating evidence highlights the role of long non-coding RNAs (lncRNAs) in cellular homeostasis, and their dysregulation in disease settings. Most lncRNAs function by interacting with proteins or protein complexes. While several orthogon
Externí odkaz:
https://doaj.org/article/eff721b69ea04988a617196e7afcaa55