Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Pieter M Cobelens"'
Autor:
Maria A Hegeman, Marije P Hennus, Pieter M Cobelens, Annemieke Kavelaars, Nicolaas J G Jansen, Marcus J Schultz, Adrianus J van Vught, Cobi J Heijnen
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57374 (2013)
BACKGROUND: Ventilator-induced lung injury (VILI) is characterized by vascular leakage and inflammatory responses eventually leading to pulmonary dysfunction. Vascular endothelial growth factor (VEGF) has been proposed to be involved in the pathogene
Externí odkaz:
https://doaj.org/article/23ad9a2e939546c2bbc726232b6fca7b
Autor:
Maria A Hegeman, Marije P Hennus, Matijs van Meurs, Pieter M Cobelens, Annemieke Kavelaars, Nicolaas J Jansen, Marcus J Schultz, Adrianus J van Vught, Grietje Molema, Cobi J Heijnen
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15653 (2010)
BackgroundLoss of integrity of the epithelial and endothelial barriers is thought to be a prominent feature of ventilator-induced lung injury (VILI). Based on its function in vascular integrity, we hypothesize that the angiopoietin (Ang)-Tie2 system
Externí odkaz:
https://doaj.org/article/7f07545ec1b245ada89475e5a61b9017
Autor:
Grietje Molema, N J.G. Jansen, Jaam Kamps, Maria A. Hegeman, Cobi Jacoba Johanna Heijnen, Marije P. Hennus, A. J. Van Vught, Marcus J. Schultz, Pieter M. Cobelens
Publikováno v:
British Journal of Pharmacology. 163:1048-1058
BACKGROUND AND PURPOSE Systemic glucocorticoid therapy may effectively attenuate lung inflammation but also induce severe side-effects. Delivery of glucocorticoids by liposomes could therefore be beneficial. We investigated if liposome-encapsulated d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f240882b4e9adc8927377d0fdf39bd37
https://doi.org/10.1111/j.1476-5381.2011.01314.x
https://doi.org/10.1111/j.1476-5381.2011.01314.x
Autor:
Jozef Kesecioglu, Cobi Jacoba Johanna Heijnen, Annemieke Kavelaars, Pieter M. Cobelens, Bart P. van Putte
Publikováno v:
Journal of Surgical Research. 153:295-301
Background Lung ischemia-reperfusion injury (LIRI) is a clinical problem observed during thoracic surgery, and adversely affects patient recovery. A better understanding of the mechanisms of LIRI could be helpful to develop new therapeutic strategies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73bbcdb44aef6410720cda89cd68d41c
https://doi.org/10.1016/j.jss.2008.04.022
https://doi.org/10.1016/j.jss.2008.04.022
Autor:
Jozef Kesecioglu, Cobi Jacoba Johanna Heijnen, Annemieke Kavelaars, Niels P. van der Kaaij, Burkhard Lachmann, Bart P. van Putte, Pieter M. Cobelens
Publikováno v:
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 137(4), 824-828. MOSBY-ELSEVIER
Objective: Lung ischemia-reperfusion injury is associated with impaired gas exchange from increased edema formation and surfactant inactivation. Surfactant replacement therapy is believed to improve gas exchange and lung function, but its effect on i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423d704ee48f50fdab82bdb0bc0eebc5
Autor:
Cobi Jacoba Johanna Heijnen, Sven Benson, Pieter M. Cobelens, Jost Langhorst, Gustav Dobos, Manfred Schedlowski, Sigrid Elsenbruch, N. Rifaie, Annemieke Kavelaars
Publikováno v:
Psychoneuroendocrinology. 32:1086-1096
Summary Objectives The mechanisms underlying the interaction of psychological stress with the disease course in inflammatory bowel diseases remain unclear. We analyzed the neuroendocrine and cellular immune responses to public speaking stress, and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b51657eed7dfd51c88fa882c64e42e
https://doi.org/10.1016/j.psyneuen.2007.09.003
https://doi.org/10.1016/j.psyneuen.2007.09.003
Autor:
A. Lucas, Annemieke Kavelaars, Sigrid Elsenbruch, Gustav Dobos, Guido Gerken, Cobi Jacoba Johanna Heijnen, Sebastian Haag, J. Langhorst, Pieter M. Cobelens, Gerald Holtmann, Manfred Schedlowski
Publikováno v:
Journal of Neuroimmunology. 182:195-203
Psychological stress has been implicated in the pathophysiology of both inflammatory and functional gastrointestinal (GI) diseases. The goal of this study was to address neuroendocrine modulation of cytokine production by peripheral blood cells in GI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0894bb9621ec0a0c7737fec10e0898d1
https://doi.org/10.1016/j.jneuroim.2006.09.011
https://doi.org/10.1016/j.jneuroim.2006.09.011
Publikováno v:
Journal of Neuroimmunology. 161:162-168
The dopamine transporter (DAT) is responsible for the re-uptake of dopamine into presynaptic nerve terminals and thereby controls dopaminergic neurotransmission. Deletion of DAT results in a hyperdopaminergic phenotype and DAT(-/-) mice are character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a524215adf7aae8d615c69433ab9311
https://doi.org/10.1016/j.jneuroim.2005.01.004
https://doi.org/10.1016/j.jneuroim.2005.01.004
Autor:
Niels Eijkelkamp, Cobi Jacoba Johanna Heijnen, Annemieke Kavelaars, Virginia M. Sanders, Pieter M. Cobelens
Publikováno v:
Journal of Neuroimmunology. 150:3-9
Beta2-adrenergic agonists have immunomodulatory effects both in vitro and in vivo. We describe that oral salbutamol (beta-adrenergic agonist) administration has tissue-specific effects on cytokine production induced by intraperitoneal (i.p.) lipopoly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4f6e0dbee573ee672398082bd7f6a4
https://doi.org/10.1016/j.jneuroim.2004.01.001
https://doi.org/10.1016/j.jneuroim.2004.01.001
Autor:
Anne Vroon, Maria Stella Lombardi, Pieter M. Cobelens, Cobi Jacoba Johanna Heijnen, Annemieke Kavelaars, Marc G. Caron, Federico Mayor
Publikováno v:
Journal of Leukocyte Biology. 75:901-909
Chemokine receptors belong to the family of G-protein-coupled receptors (GPCR). Phosphorylation of GPCR by GPCR kinases (GRKs) is considered to play an important role in desensitization of these receptors. We have recently shown in patients with rheu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::681cb10bb650725360c7ac1e39e17946
https://doi.org/10.1189/jlb.0403136
https://doi.org/10.1189/jlb.0403136