Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Pieter L.B. Bruynzeel"'
1
Late asthmatic responses after exercise challenge are reproducible
Autor: Egidius A.H. Panis, Bernardus Speelberg, Pieter L.B. Bruynzeel, Derk Bijl, Cees L. A. van Herwaarden
Publikováno v: The Journal of allergy and clinical immunology. 87(6)
In this study the reproducibility of a late asthmatic reaction (LAR) after exercise challenge (EC) has been documented. Eighty-three hospitalized patients with asthma were challenged with exercise. The patients were examined according to a standardiz
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed04f9a501a5b2d967c057103ed1cb0d
https://pubmed.ncbi.nlm.nih.gov/2045617
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2
Platelet-activating factor (PAF-acether) induced leukotriene C4 formation and luminol dependent chemiluminescence by human eosinophils
Autor: Leo Koenderman, Jan Verhagen, Pieter L.B. Bruynzeel, P.T.M. Kok, M.L. Hameling
Publikováno v: Pharmacological Research Communications. 18:61-69
Human eosinophils are capable of synthesizing almost exclusively the strongly spasmogenic compound LTC4 when stimulated with either the calcium ionophore A 23187 or opsonized zymosan (OZ). Although PAF-acether in concentrations ranging from 10 nM to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64b76d554afdee79b2c5496c5cbef70b
https://doi.org/10.1016/0031-6989(86)90039-1
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3
On the optimal conditions of LTC4 formation by human eosinophils in vitro
Autor: Pieter L.B. Bruynzeel, Paul T.M. Kok, Remco J. Viëtor, Jan Verhagen
Publikováno v: Prostaglandins, Leukotrienes and Medicine. 20:11-22
The optimal conditions for the -in vitro- LTC4 formation by the human eosinophil, isolated from peripheral blood, have been investigated in detail. LTC4 formation was found strongly Ca2+ and ionophore dependent and was complete after 20 min. Maximal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca721a6528dbf65d376352814e9e5cc7
https://doi.org/10.1016/0262-1746(85)90090-3
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4
Separation and quantitation of leukotrienes by reversed-phase high-performance liquid chromatography
Autor: Pauline Walstra, Gerrit A. Veldink, Jan Verhagen, Pieter L.B. Bruynzeel, Johannes F.G. Vliegenthart
Publikováno v: Prostaglandins, Leukotrienes and Medicine. 13:15-20
A rapid and sensitive reversed-phase HPLC procedure is reported which allows the simultaneous separation and quantitation of LTC4, 11t-LTC4, LTD4, LTB4, 12epi,6t,8c-LTB4, 6t-LTB4 + 12epi,6t-LTB4, two trihydroxy-eicosatetraenoic acids tentatively iden
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e059d8508ccd428a33ec6a901798f380
https://doi.org/10.1016/0262-1746(84)90097-0
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5
Evaluation of total and specific IgE determinations in normal children and children suffering from asthmatic bronchitis with suspected allergic disease
Autor: Leonard A.M.J. Houben, Pieter L.B. Bruynzeel
Publikováno v: Clinica Chimica Acta. 112:315-323
In young children with suspected allergic disease skin testing might to some extent be replaced by total and specific IgE determinations. Total IgE levels could be determined in these cases by the paper radioimmunosorbent test (PRIST) and be related
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446dd2e22188dee110ceddb13d55757d
https://doi.org/10.1016/0009-8981(81)90454-x
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6
Exclusive leukotriene C4 synthesis by purified human eosinophils induced by opsonized zymosan
Autor: Pieter L.B. Bruynzeel, Jan Verhagen, Maartje L. Hamelink, Paul T.M. Kok, Arda M. Kijne
Publikováno v: FEBS Letters. (2):350-354
Purified human eosinophils were challenged with N -formyl-methionyl-leucyl-phenylalanine, leukotriene B 4 , platelet-activating-factor, valyl-glycyl-seryl-glutamic acid, phorbol myristate acetate, zymosan, opsonized zymosan and the calcium ionophore
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4099e41d93b92694fb4af473094a337
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7
Leukotriene C4 formation by purified human eosinophils can be induced by arachidonic acid in the absence of calcium-inophore A23187
Autor: Gerrit A. Veldink, Leo Koenderman, Maartje L. Hamelink, G. M. Kijne, P.T.M. Kok, Pieter L.B. Bruynzeel, Jan Verhagen
Publikováno v: Agents and Actions. 26:96-98
Addition of arachidonic acid (50 microM) to purified human eosinophils leads to the formation of considerable amounts of LTC4 [11.3 +/- 1.3) x 10(6) molecules/cell, mean +/- SEM, n = 10), 15-HETE [412 +/- 142) x 10(6) molecules/cell, mean +/- SEM, n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0421bde82815ae9a0076ef1946fc1c05
https://doi.org/10.1007/bf02126571
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10
The excretion of leukotriene E4 into urine following inhalation of leukotriene D4 by human individuals
Autor: Johannes F.G. Vliegenthart, Elisabeth H. Bel, Jan Verhagen, Gerarda M. Kijne, Gerrit A. Veldink, Peter J. Sterk, Pieter L.B. Bruynzeel
Publikováno v: Biochemical and biophysical research communications, 148(2), 864-868. Academic Press Inc.
Biochemical and biophysical research communications, 148(2), 864. Academic Press
Healthy volunteers underwent bronchial challenge with increasing doses of nebulized leukotriene D4 (0.007 - 200 nmol) at 15 min intervals. Total amounts of 200 nmol (females) and 400 nmol (males) were inhaled, corresponding to approximately 100 nmol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c993dbc4c116eea5044862d4b843c586
https://pubmed.ncbi.nlm.nih.gov/3689376
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