Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Pieter J. Peeters"'
Autor:
Viola Volpato, James Smith, Cynthia Sandor, Janina S. Ried, Anna Baud, Adam Handel, Sarah E. Newey, Frank Wessely, Moustafa Attar, Emma Whiteley, Satyan Chintawar, An Verheyen, Thomas Barta, Majlinda Lako, Lyle Armstrong, Caroline Muschet, Anna Artati, Carlo Cusulin, Klaus Christensen, Christoph Patsch, Eshita Sharma, Jerome Nicod, Philip Brownjohn, Victoria Stubbs, Wendy E. Heywood, Paul Gissen, Roberta De Filippis, Katharina Janssen, Peter Reinhardt, Jerzy Adamski, Ines Royaux, Pieter J. Peeters, Georg C. Terstappen, Martin Graf, Frederick J. Livesey, Colin J. Akerman, Kevin Mills, Rory Bowden, George Nicholson, Caleb Webber, M. Zameel Cader, Viktor Lakics
Publikováno v:
Stem Cell Reports, Vol 11, Iss 4, Pp 897-911 (2018)
Summary: Reproducibility in molecular and cellular studies is fundamental to scientific discovery. To establish the reproducibility of a well-defined long-term neuronal differentiation protocol, we repeated the cellular and molecular comparison of th
Externí odkaz:
https://doaj.org/article/de4461b1cd604cd1b890c370ecec071c
Autor:
An Verheyen, Annick Diels, Joke Reumers, Kirsten Van Hoorde, Ilse Van den Wyngaert, Constantin van Outryve d’Ydewalle, An De Bondt, Jacobine Kuijlaars, Louis De Muynck, Ronald De Hoogt, Alexis Bretteville, Steffen Jaensch, Arjan Buist, Alfredo Cabrera-Socorro, Selina Wray, Andreas Ebneth, Peter Roevens, Ines Royaux, Pieter J. Peeters
Publikováno v:
Stem Cell Reports, Vol 11, Iss 2, Pp 363-379 (2018)
Summary: Tauopathies such as frontotemporal dementia (FTD) remain incurable to date, partially due to the lack of translational in vitro disease models. The MAPT gene, encoding the microtubule-associated protein tau, has been shown to play an importa
Externí odkaz:
https://doaj.org/article/301136220c5f4b20bc2ad49e591d873f
Autor:
Srinivas Niranj Chandrasekaran, Jeanelle Ackerman, Eric Alix, D. Michael Ando, John Arevalo, Melissa Bennion, Nicolas Boisseau, Adriana Borowa, Justin D. Boyd, Laurent Brino, Patrick J. Byrne, Hugo Ceulemans, Carolyn Ch’ng, Beth A. Cimini, Djork-Arne Clevert, Nicole Deflaux, John G Doench, Thierry Dorval, Regis Doyonnas, Vincenza Dragone, Ola Engkvist, Patrick W. Faloon, Briana Fritchman, Florian Fuchs, Sakshi Garg, Tamara J. Gilbert, David Glazer, David Gnutt, Amy Goodale, Jeremy Grignard, Judith Guenther, Yu Han, Zahra Hanifehlou, Santosh Hariharan, Desiree Hernandez, Shane R Horman, Gisela Hormel, Michael Huntley, Ilknur Icke, Makiyo Iida, Christina B. Jacob, Steffen Jaensch, Jawahar Khetan, Maria Kost-Alimova, Tomasz Krawiec, Daniel Kuhn, Charles-Hugues Lardeau, Amanda Lembke, Francis Lin, Kevin D. Little, Kenneth R. Lofstrom, Sofia Lotfi, David J. Logan, Yi Luo, Franck Madoux, Paula A. Marin Zapata, Brittany A. Marion, Glynn Martin, Nicola Jane McCarthy, Lewis Mervin, Lisa Miller, Haseeb Mohamed, Tiziana Monteverde, Elizabeth Mouchet, Barbara Nicke, Arnaud Ogier, Anne-Laure Ong, Marc Osterland, Magdalena Otrocka, Pieter J. Peeters, James Pilling, Stefan Prechtl, Chen Qian, Krzysztof Rataj, David E Root, Sylvie K. Sakata, Simon Scrace, Hajime Shimizu, David Simon, Peter Sommer, Craig Spruiell, Iffat Sumia, Susanne E Swalley, Hiroki Terauchi, Amandine Thibaudeau, Amy Unruh, Jelle Van de Waeter, Michiel Van Dyck, Carlo van Staden, Michał Warchoł, Erin Weisbart, Amélie Weiss, Nicolas Wiest-Daessle, Guy Williams, Shan Yu, Bolek Zapiec, Marek Żyła, Shantanu Singh, Anne E. Carpenter
Image-based profiling has emerged as a powerful technology for various steps in basic biological and pharmaceutical discovery, but the community has lacked a large, public reference set of data from chemical and genetic perturbations. Here we present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ad294298f87b0d35776a491fba28d7f
https://doi.org/10.1101/2023.03.23.534023
https://doi.org/10.1101/2023.03.23.534023
Autor:
Laure Cougnaud, Hugo Ceulemans, Seong Joo Koo, Jelle Van de Waeter, Jean-Marc Neefs, Emmanuel Gustin, Jörg K. Wegner, Hinrich W. H. Göhlmann, Margino Steemans, Ilse Van den Wyngaert, Michael J. Cox, Soulaiman Benalla, Steffen Jaensch, Pieter J. Peeters, Yolanda T. Chong, Daan Seynaeve, Dmitry Malkov, Mart Bittremieux
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Phenomic profiles are high-dimensional sets of readouts that can comprehensively capture the biological impact of chemical and genetic perturbations in cellular assay systems. Phenomic profiling of compound libraries can be used for compound target i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ad9da8d1ef2e11a2c7e73ab2912140
Autor:
George Nicholson, Lyle Armstrong, Caroline Muschet, Adam E. Handel, Wendy E. Heywood, Eshita Sharma, Pieter J. Peeters, Philip W. Brownjohn, Frank Wessely, Georg C. Terstappen, Carlo Cusulin, Majlinda Lako, Katharina Janssen, Viktor Lakics, Satyan Chintawar, Kevin Mills, Jerzy Adamski, Thomas Barta, Anna Baud, Caleb Webber, Viola Volpato, Moustafa Attar, Roberta De Filippis, Janina S. Ried, Frederick J. Livesey, Peter Reinhardt, Martin Graf, Cynthia Sandor, Jérôme Nicod, Rory Bowden, M. Zameel Cader, Sarah E. Newey, Ines Royaux, Emma S. Whiteley, Aanna Artati, Victoria Stubbs, Paul Gissen, James Smith, An Verheyen, Christoph Patsch, Klaus Christensen, Colin J. Akerman
Publikováno v:
Stem Cell Reports
Stem Cell Rep. 11, 897-911 (2018)
Stem Cell Reports, Vol 11, Iss 4, Pp 897-911 (2018)
Stem Cell Rep. 11, 897-911 (2018)
Stem Cell Reports, Vol 11, Iss 4, Pp 897-911 (2018)
Summary Reproducibility in molecular and cellular studies is fundamental to scientific discovery. To establish the reproducibility of a well-defined long-term neuronal differentiation protocol, we repeated the cellular and molecular comparison of the
Autor:
Caleb Webber, Olukunbi Mosaku, Lyle Armstrong, Kevin Mills, Anna Baud, Stephane Camuzeaux, J McCormick, Jane Vowles, Paul Gissen, Francesca Mazzacuva, M Z Cader, Pieter J. Peeters, Majlinda Lako, F Wessely, Wendy E. Heywood, Sally A. Cowley, M Tuefferd, Daniel Little
Publikováno v:
Analytical Chemistry. 89:2440-2448
Induced pluripotent stem cells have great potential as a human model system in regenerative medicine, disease modeling, and drug screening. However, their use in medical research is hampered by laborious reprogramming procedures that yield low number
Autor:
P. Roevens, Constantin d’Ydewalle, Andreas Ebneth, Jacobine Kuijlaars, Selina Wray, Annick Diels, Alexis Bretteville, Arjan Buist, An Verheyen, Joke Reumers, Alfredo Cabrera-Socorro, Ronald de Hoogt, Louis De Muynck, Ines Royaux, Kirsten Van Hoorde, An De Bondt, Ilse Van den Wyngaert, Pieter J. Peeters, Steffen Jaensch
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 11, Iss 2, Pp 363-379 (2018)
Stem Cell Reports, Vol 11, Iss 2, Pp 363-379 (2018)
Summary Tauopathies such as frontotemporal dementia (FTD) remain incurable to date, partially due to the lack of translational in vitro disease models. The MAPT gene, encoding the microtubule-associated protein tau, has been shown to play an importan
Autor:
Evian Gordon, Wilhelmus Drinkenburg, C. P. M. Veth, Pieter J. Peeters, Martijn Arns, Willem Talloen, Jan K. Buitelaar
Publikováno v:
Psychiatry Research, 219, 221-4
Psychiatry Research, 219, 1, pp. 221-4
Psychiatry Research, 219(1), 221-224. Elsevier Ireland Ltd
Psychiatry Research, 219, 1, pp. 221-4
Psychiatry Research, 219(1), 221-224. Elsevier Ireland Ltd
This study could not confirm the association between the Catechol-O-Methyltransferase Val158Met polymorphism (COMT) and electroencephalographic (EEG) alpha peak frequency (APF) in two independent cohorts of 187 (96 depressed and 91 healthy participan
Autor:
Amy Axel, Dirk Wuyts, Nele Vloemans, Pieter J. Peeters, Lut Janssen, Ronald de Hoogt, Eberhard Krausz, Emmanuel Gustin, Thierry Grand-Perret, Brett Hall, Sandy Frans, Miroslav Cik, Frans Cornelissen
Publikováno v:
SLAS Discovery. 18:54-66
For drug discovery, cell-based assays are becoming increasingly complex to mimic more realistically the nature of biological processes and their diversifications in diseases. Multicellular co-cultures embedded in a three-dimensional (3D) matrix have
Autor:
Hassan Rahmoune, Sabine Bahn, Paul C. Guest, Laura W. Harris, Daniel Martins-de-Souza, Nancy Aerts, Ilse Lenaerts, Murtada Alsaif, Bob Amess, Agnes Ernst, Pieter J. Peeters
Publikováno v:
BMC Research Notes, Vol 5, Iss 1, p 146 (2012)
BMC Research Notes
BMC Research Notes
Background: Establishing preclinical models is essential for novel drug discovery in schizophrenia. Most existing models are characterized by abnormalities in behavioral readouts, which are informative, but do not necessarily translate to the symptom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6dc7ec3cdc29714927d7bddeb8caa7f
https://ora.ox.ac.uk/objects/uuid:d8a5e0f4-4f4b-439e-8c73-c0cc894185e8
https://ora.ox.ac.uk/objects/uuid:d8a5e0f4-4f4b-439e-8c73-c0cc894185e8