Zobrazeno 1 - 10
of 398
pro vyhledávání: '"Pieter H, Reitsma"'
Autor:
Daniël Verhoef, Koen M. Visscher, C. Ruben Vosmeer, Ka Lei Cheung, Pieter H. Reitsma, Daan P. Geerke, Mettine H. A. Bos
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
A major drawback in the clinical use of the oral anticoagulants that directly inhibit factor Xa in order to prevent blood clot formation is the potential for life threatening bleeding events. Here the authors describe factor Xa variants that are refr
Externí odkaz:
https://doaj.org/article/b141be2853c5434db46bb976a6a0ac12
Autor:
Marisa L R Cunha, Joost C M Meijers, Frits R Rosendaal, Astrid van Hylckama Vlieg, Pieter H Reitsma, Saskia Middeldorp
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187699 (2017)
BACKGROUND:Family studies have shown a strong heritability component for venous thromboembolism (VTE), but established genetic risk factors are present in only half of VTE patients. AIM:To identify genetic risk factors in two large families with unex
Externí odkaz:
https://doaj.org/article/fe455552697543c183672a2ddff7be48
Publikováno v:
Thrombosis Research, 198, 154-162. PERGAMON-ELSEVIER SCIENCE LTD
A wide variety of animal models on thrombosis and hemostasis are used in thrombosis and hemostasis research for the preclinical assessment of hemostatic agents. While the vertebrate coagulome is highly conserved, human and animal plasmas differ consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26af339892b1b7b9637b010959d377a8
https://doi.org/10.1016/j.thromres.2020.11.023
https://doi.org/10.1016/j.thromres.2020.11.023
Autor:
Nienke van Rein, Willem M Lijfering, Mettine H A Bos, Martien H Herruer, Helga W Vermaas, Felix J M van der Meer, Pieter H Reitsma
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0164485 (2016)
Risk scores for patients who are at high risk for major bleeding complications during treatment with vitamin K antagonists (VKAs) do not perform that well. BLEEDS was initiated to search for new biomarkers that predict bleeding in these patients.To d
Externí odkaz:
https://doaj.org/article/8e4556d104514dd691ba79eb7bb4ff79
Publikováno v:
Seminars in Thrombosis and Hemostasis. 46:986-998
The direct oral anticoagulants targeting coagulation factor Xa or thrombin are widely used as alternatives to vitamin K antagonists in the management of venous thromboembolism and nonvalvular atrial fibrillation. In case of bleeding or emergency surg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb49b5ee0c496de367c4ecb40017c31c
https://doi.org/10.1055/s-0040-1709134
https://doi.org/10.1055/s-0040-1709134
Autor:
Audrey C A Cleuren, Vicky T Blankevoort, Janna A van Diepen, Daniël Verhoef, Peter J Voshol, Pieter H Reitsma, Bart J M van Vlijmen
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131859 (2015)
Obesity is associated with a hypercoagulable state and increased risk for thrombotic cardiovascular events.Establish the onset and reversibility of the hypercoagulable state during the development and regression of nutritionally-induced obesity in mi
Externí odkaz:
https://doaj.org/article/a06c9576e6704ba9ba6a1579c9ac5cc9
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127469 (2015)
Thyroid dysfunction is associated with changes in coagulation. The aim of our study was to gain more insight into the role of thyroid hormone in coagulation control. C57Black/6J mice received a low-iodine diet and drinking water supplemented with per
Externí odkaz:
https://doaj.org/article/9b3c66dc3a0d49968f1b93ba23c11a1a
Autor:
Ka Lei Cheung, Gerry A. F. Nicolaes, Mark Schreuder, Pieter H. Reitsma, Mettine H.A. Bos, Xiaosong Liu
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology, 41(8), 2263-2276. LIPPINCOTT WILLIAMS & WILKINS
Arteriosclerosis Thrombosis and Vascular Biology, 41(8), 2263-2276. LIPPINCOTT WILLIAMS & WILKINS
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis Thrombosis and Vascular Biology, 41(8), 2263-2276. LIPPINCOTT WILLIAMS & WILKINS
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: The Australian snake venom ptFV (Pseudonaja textilis venom-derived factor V) variant retains cofactor function despite APC (activated protein C)-dependent proteolysis. Here, we ai
Objective: The Australian snake venom ptFV (Pseudonaja textilis venom-derived factor V) variant retains cofactor function despite APC (activated protein C)-dependent proteolysis. Here, we ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0177646b148d48e28357e8ec2dae81
https://hdl.handle.net/1887/3230184
https://hdl.handle.net/1887/3230184
Autor:
Gürbey Ocak, Christiane Drechsler, Carla Y Vossen, Hans L Vos, Frits R Rosendaal, Pieter H Reitsma, Michael M Hoffmann, Winfried März, Willem H Ouwehand, Raymond T Krediet, Elisabeth W Boeschoten, Friedo W Dekker, Christoph Wanner, Marion Verduijn
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97251 (2014)
The protein C pathway plays an important role in the maintenance of endothelial barrier function and in the inflammatory and coagulant processes that are characteristic of patients on dialysis. We investigated whether common single nucleotide variant
Externí odkaz:
https://doaj.org/article/e4e2071c45534a77a476402036bd1f81
Publikováno v:
Haematologica, Vol 98, Iss 1 (2013)
Tissue factor activation (decryption) has been proposed to be dependent on the cysteine 186-cysteine 209 allosteric disulfide in the tissue factor extracellular domain. Tissue factor procoagulant activity is under the control of protein disulfide iso
Externí odkaz:
https://doaj.org/article/3d65dbe50a6b4f6692c003c44214080b