Výsledky vyhledávání - "Pieter H, Griffioen"

Akademický článek

Global DNA (hydroxy)methylation is stable over time under several storage conditions and temperatures

Autor: Helen R. Gosselt, Pieter H. Griffioen, Bertrand D. van Zelst, Natanja Oosterom, Robert de Jonge, Sandra G. Heil

Publikováno v: Epigenetics, Vol 16, Iss 1, Pp 45-53 (2021)

Background: Epigenetic markers are often quantified and related to disease in stored samples. While, effects of storage on stability of these markers have not been thoroughly examined. In this longitudinal study, we investigated the influence of stor

Externí odkaz: https://doaj.org/article/ee25caab32914f6885619b8238933cdd

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Simultaneous quantification of tryptophan metabolites by liquid chromatography tandem mass spectrometry during early human pregnancy

Autor: Sofie K M, van Zundert, Pieter H, Griffioen, Lenie, van Rossem, Sten P, Willemsen, Yolanda B, de Rijke, Ron H N, van Schaik, Régine P M, Steegers-Theunissen, Mina, Mirzaian

Publikováno v: Clinical Chemistry and Laboratory Medicine, 61(3), 442-451. De Gruyter

Objectives In this study we describe the development and validation of a liquid chromatography mass spectrometry method (LC-MS/MS) to quantify five tryptophan (TRP) metabolites within the kynurenine– and serotonin pathway and apply the method to se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736c15c21e5b42a4ee902d4d36c69c47
https://doi.org/10.1515/cclm-2022-0790

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Akademický článek

Lower S-adenosylmethionine levels and DNA hypomethylation of placental growth factor (PlGF) in placental tissue of early-onset preeclampsia-complicated pregnancies.

Autor: Sandra G Heil, Emilie M Herzog, Pieter H Griffioen, Bertrand van Zelst, Sten P Willemsen, Yolanda B de Rijke, Regine P M Steegers-Theunissen, Eric A P Steegers

Publikováno v: PLoS ONE, Vol 14, Iss 12, p e0226969 (2019)

IntroductionThe pathophysiology of preeclampsia is largely unknown. Serum placental induced growth factor (PlGF) levels are decreased during second trimester pregnancy. Aberrant DNA methylation is suggested to be involved in the etiology of preeclamp

Externí odkaz: https://doaj.org/article/297c506e5fd242ddb78803be2212945d

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Is Methotrexate Safe for Men with an Immune-Mediated Inflammatory Disease and an Active Desire to Become a Father? Results of a Prospective Cohort Study ( (iFAME-MTX)

Autor: Luis Fernando Perez-Garcia, Esther Röder, Bouwe P. Krijthe, Laura Kranenburg-van Kopen, Roxanne van Adrichem, Els Zirkzee, Pieter H. Griffioen, Kris Peeters, Marry Lin, Eduard A. Struijs, Gerrit Jansen, Martijn B.A. van Doorn, Robert de Jonge, Gert R. Dohle, Radboud J.E.M. Dolhain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::24869ae50a6cfa4ce3e55fc3f6e990ea
https://doi.org/10.2139/ssrn.4359628

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Akademický článek

Global methylation in relation to methotrexate-induced oral mucositis in children with acute lymphoblastic leukemia.

Autor: Natanja Oosterom, Pieter H Griffioen, Marissa A H den Hoed, Rob Pieters, Robert de Jonge, Wim J E Tissing, Marry M van den Heuvel-Eibrink, Sandra G Heil

Publikováno v: PLoS ONE, Vol 13, Iss 7, p e0199574 (2018)

BACKGROUND:Children with acute lymphoblastic leukemia (ALL) often suffer from toxicity of chemotherapeutic drugs such as Methotrexate (MTX). Previously, we reported that 20% of patients receiving high-dose MTX developed oral mucositis. MTX inhibits f

Externí odkaz: https://doaj.org/article/436c64c86ccf458d979c75358d09a3c1

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Global DNA (hydroxy)methylation is stable over time under several storage conditions and temperatures

Autor: Natanja Oosterom, Helen R. Gosselt, Sandra G. Heil, Robert de Jonge, Pieter H. Griffioen, Bertrand D. van Zelst

Publikováno v: Epigenetics, 16(1), 1-9. Landes Bioscience
Epigenetics
article-version (VoR) Version of Record
Gosselt, H R, Griffioen, P H, van Zelst, B D, Oosterom, N, de Jonge, R & Heil, S G 2020, ' Global DNA (hydroxy)methylation is stable over time under several storage conditions and temperatures ', Epigenetics, pp. 1-9 . https://doi.org/10.1080/15592294.2020.1786318
Epigenetics, 1-9. Landes Bioscience
STARTPAGE=1;ENDPAGE=9;ISSN=1559-2294;TITLE=Epigenetics

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c560f6373bc1967524ad2574ef4e14e
https://pure.eur.nl/en/publications/9e2973ae-792a-4543-b9ad-00ed545b39b7

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Measurement of total Transcobalamin employing a commercially available assay for Active B12

Autor: Jan Lindemans, Dianne H.K. van Dam-Nolen, Pieter H. Griffioen, Sandra G. Heil

Publikováno v: Clinical Biochemistry, 50(18), 1030-1033. Elsevier Inc.

Introduction Vitamin B12 deficiency is mostly caused by insufficient gastro-intestinal absorption and in rare conditions by Transcobalamin (TC) deficiency. Unsaturated Transcobalamin (apoTC) can be measured by a binding assay using radiolabeled cobal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ac54a6080f6e51de04e8d919cbce853
https://doi.org/10.1016/j.clinbiochem.2017.08.009

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Lower S-adenosylmethionine levels and DNA hypomethylation of placental growth factor (PlGF) in placental tissue of early-onset preeclampsia-complicated pregnancies

Autor: Emilie M. Herzog, Sten P. Willemsen, Pieter H. Griffioen, Régine P.M. Steegers-Theunissen, Bertrand D. van Zelst, Yolanda B. de Rijke, Eric A.P. Steegers, Sandra G. Heil

Publikováno v: PLoS ONE, Vol 14, Iss 12, p e0226969 (2019)
PLoS ONE
PLoS One (print), 14(12):e0226969. Public Library of Science

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e0f75fc705ad8d27b35abd751ac720
https://doaj.org/article/297c506e5fd242ddb78803be2212945d

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Polymorphisms correlated with the clinical outcome of locally advanced or metastatic colorectal cancer patients treated with ALIRI vs. FOLFIRI

Autor: Elisa Giovannetti, Godefridus J. Peters, Robert de Jonge, Pieter H. Griffioen, Axel R. Hanauske, Ana Barcelos, Mina Maftouh

Publikováno v: Pteridines, 24(1), 69-79. International Society of Pteridinology
Barcelos, A, Giovannetti, E, de Jonge, R, Maftouh, M, Griffioen, P, Hanauske, A R & Peters, G J 2013, ' Polymorphisms correlated with the clinical outcome of locally advanced or metastatic colorectal cancer patients treated with ALIRI vs. FOLFIRI ', Pteridines, vol. 24, no. 1, pp. 69-79 . https://doi.org/10.1515/pterid-2013-0021
Pteridines, Vol 24, Iss 1, Pp 69-79 (2013)

Leucovorin-modulated 5-fluorouracil (5-FU) plus irinotecan (FOLFIRI) is the most common treatment of metastatic colorectal cancer (CRC). 5-FU inhibits thymidylate synthase (TS) and irinotecan topoisomerase I, leading to inhibition of DNA replication

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4471dbed260d4a9fa5d0d3fe046ea2b
https://research.vumc.nl/en/publications/ead7a6a9-dc1e-44bd-be40-7bf274f7ca51

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Detection and allele-frequencies of the 833TC, 844ins68 and a novel mutation in the cystathionine beta-synthase gene

Autor: R. Montserrate Brouns, Robert de Jonge, Pieter H. Griffioen, Bertrand D. van Zelst, Jan Lindemans

Publikováno v: Clinica Chimica Acta, 354(1-2), 191-194. Elsevier

Background The most common 833T>C/844ins68 in cis double mutation in the cystathionine beta synthase (CBS) gene probably is non-pathogenic because the 68-bp insertion eliminates the 833T>C mutation due to alternative splicing. However, allele frequen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df954509188d0cb1996bd0936e750f19
https://pubmed.ncbi.nlm.nih.gov/15748616

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