Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Pieter C van Breugel"'
Autor:
Li Li, Alejandro P. Ugalde, Colinda L. G. J. Scheele, Sebastian M. Dieter, Remco Nagel, Jin Ma, Abhijeet Pataskar, Gozde Korkmaz, Ran Elkon, Miao-Ping Chien, Li You, Pin-Rui Su, Onno B. Bleijerveld, Maarten Altelaar, Lyubomir Momchev, Zohar Manber, Ruiqi Han, Pieter C. van Breugel, Rui Lopes, Peter ten Dijke, Jacco van Rheenen, Reuven Agami
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-28 (2021)
Abstract Background Frequent activation of the co-transcriptional factor YAP is observed in a large number of solid tumors. Activated YAP associates with enhancer loci via TEAD4-DNA-binding protein and stimulates cancer aggressiveness. Although thous
Externí odkaz:
https://doaj.org/article/c775eb768cb945179e71e99f571ae872
The epidermal growth factor receptor (EGFR) is a member of the receptor tyrosine kinase family (RTK) of transmembrane receptors, known to regulate many key cellular processes, including growth, proliferation, and differentiation. Its expression, acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0a80e832d591b47d598c037e8869095
https://doi.org/10.1101/2022.02.02.478771
https://doi.org/10.1101/2022.02.02.478771
Autor:
Michel Strubin, Rudolf K. F. Beran, Laetitia Gerossier, Simon P. Fletcher, Christine M. Livingston, Fabien Abdul, Pieter C van Breugel, Henrik Mueller, Congrong Niu, Adrien Decorsiere, Olivier Hantz
Publikováno v:
Nature
Nature, Vol. 531, No 7594 (2016) pp. 386-389
Nature, Nature Publishing Group, 2016, 531 (7594), pp.386-389. ⟨10.1038/nature17170⟩
Nature, Vol. 531, No 7594 (2016) pp. 386-389
Nature, Nature Publishing Group, 2016, 531 (7594), pp.386-389. ⟨10.1038/nature17170⟩
Chronic hepatitis B virus infection is a leading cause of cirrhosis and liver cancer. Hepatitis B virus encodes the regulatory HBx protein whose primary role is to promote transcription of the viral genome, which persists as an extrachromosomal DNA c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64462e2ec856d32508eaa7900d6ba34d
http://archive-ouverte.unige.ch/unige:85682
http://archive-ouverte.unige.ch/unige:85682
Autor:
Zohar Manber, Behzad Moumbeini, Yongsoo Kim, Romy van Vliet, Lars Custers, Remco Nagel, Reuven Agami, Gozde Korkmaz, Rui Lopes, Ran Elkon, Pieter C van Breugel, Sonia Aristin Revilla, Wilbert Zwart
Publikováno v:
Cancer Letters, 436, 87-95. Elsevier Ireland Ltd
Lopes, R, Korkmaz, G, Revilla, S A, van Vliet, R, Nagel, R, Custers, L, Kim, Y, van Breugel, P C, Zwart, W, Moumbeini, B, Manber, Z, Elkon, R & Agami, R 2018, ' CUEDC1 is a primary target of ERα essential for the growth of breast cancer cells ', Cancer Letters, vol. 436, pp. 87-95 . https://doi.org/10.1016/j.canlet.2018.08.018
Lopes, R, Korkmaz, G, Revilla, S A, van Vliet, R, Nagel, R, Custers, L, Kim, Y, van Breugel, P C, Zwart, W, Moumbeini, B, Manber, Z, Elkon, R & Agami, R 2018, ' CUEDC1 is a primary target of ERα essential for the growth of breast cancer cells ', Cancer Letters, vol. 436, pp. 87-95 . https://doi.org/10.1016/j.canlet.2018.08.018
Breast cancer is the most prevalent type of malignancy in women with ∼1.7 million new cases diagnosed annually, of which the majority express ERα (ESR1), a ligand-dependent transcription factor. Genome-wide chromatin binding maps suggest that ERα
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8845cb8fdf08bbb66a83741bcc310d25
https://pure.eur.nl/en/publications/574a5697-1925-4c32-a6fb-8e720de1e1fe
https://pure.eur.nl/en/publications/574a5697-1925-4c32-a6fb-8e720de1e1fe
Autor:
Ran Elkon, Eric Pintó Barberà, Dannys Jorge Martínez-Herrera, Reuven Agami, Maite Huarte, Alejandro Pineiro Ugalde, Ruiqi Han, Naama Messika-Gold, Li Li, Rui Lopes, Pieter C van Breugel, Gozde Korkmaz, Elzo de Wit, Jarno Drost, Ricardo J Soares, Hans Teunissen, Annita Louloupi, Boye Schnack Nielsen, Kim Holmstrøm, Fabricio Loayza-Puch
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 46(8), 4213-4227. Oxford University Press
Nucleic Acids Research, 46(8), 4213-4227. Oxford University Press
Oncogene-induced senescence (OIS), provoked in response to oncogenic activation, is considered an important tumor suppressor mechanism. Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nt without a protein-coding capacity. Functional st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8257f2f707b429a33cc602f5d798514c
https://pubmed.ncbi.nlm.nih.gov/29481642
https://pubmed.ncbi.nlm.nih.gov/29481642
Autor:
Adrien Decorsiere, Eva Isabelle Robert, Michel Strubin, Olivier Hantz, Henrik Mueller, Pieter C van Breugel, Fabien Zoulim
Publikováno v:
Hepatology (Baltimore Md.)
Hepatology
Hepatology, Wiley-Blackwell, 2012, 56 (6), pp.2116-2124. ⟨10.1002/hep.25928⟩
Hepatology, Vol. 56, No 6 (2012) pp. 2116-2124
Hepatology
Hepatology, Wiley-Blackwell, 2012, 56 (6), pp.2116-2124. ⟨10.1002/hep.25928⟩
Hepatology, Vol. 56, No 6 (2012) pp. 2116-2124
Chronic hepatitis B virus (HBV) infection is a major risk factor for liver cancer development. HBV encodes the hepatitis B virus X (HBx) protein that promotes transcription of the viral episomal DNA genome by the host cell RNA polymerase II. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33392246caa4ddc4152ce8d132c95153
http://archive-ouverte.unige.ch/unige:24257
http://archive-ouverte.unige.ch/unige:24257
Publikováno v:
Nat Struct Mol Biol
Nature Structural & Molecular Biology, Vol. 17, No 1 (2010) pp. 105-111
Nature Structural & Molecular Biology, Vol. 17, No 1 (2010) pp. 105-111
The cullin 4-DNA-damage-binding protein 1 (CUL4-DDB1) ubiquitin ligase machinery regulates diverse cellular functions and can be subverted by pathogenic viruses. Here we report the crystal structure of DDB1 in complex with a central fragment of hepat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7ee70719c2035cd2a078f8f0cd9f8b
http://archive-ouverte.unige.ch/unige:20645
http://archive-ouverte.unige.ch/unige:20645
Publikováno v:
Journal of virology. 73(1)
Many enteroviruses, members of the family Picornaviridae , cause a rapid and drastic inhibition of host cell protein synthesis during infection, a process referred to as host cell shutoff. Poliovirus, one of the best-studied enteroviruses, causes mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b273b56e4a558b1553d4e9528ebd7b
https://pubmed.ncbi.nlm.nih.gov/9847378
https://pubmed.ncbi.nlm.nih.gov/9847378
Autor:
Koos Rooijers, Olaf van Tellingen, Axel Bex, Fabricio Loayza-Puch, Alejandro Pineiro Ugalde, Jelle Wesseling, Levi C.M. Buil, Jelle Zijlstra, Reuven Agami, Joachim A.F. Oude Vrielink, Ingrid Hofland, Rui Lopes, Pieter C van Breugel
Publikováno v:
Nature, 530(7591), 490-+. Nature Publishing Group
Nature
Nature
Tumour growth and metabolic adaptation may restrict the availability of certain amino acids for protein synthesis. It has recently been shown that certain types of cancer cells depend on glycine, glutamine, leucine and serine metabolism to proliferat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368cb7c8ba94cea2ab4cf0c6c705f1d9