Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Pieter Zandberg"'
Autor:
Carol Thijssen-van Zuylen, Willem G.E.J. Schoonen, Pieter Zandberg, Martin J. Smit, G. Jean Horbach, Joop H. J. van Nesselrooij, Jan-Remt Mellema, Jack T. W. E. Vogels, Albert C. Tas, Jan-Peter H. T. M. Ploemen, Cathelijne P. A. M. Kloks
Publikováno v:
Toxicological Sciences. 98:271-285
1H nuclear magnetic resonance (NMR) spectroscopy of rat urine in combination with pattern recognition analysis was evaluated for early noninvasive detection of toxicity of investigational chemical entities. Bromobenzene (B) and paracetamol (P) were a
Autor:
Martin J. Smit, G. Jean Horbach, Jan-Peter H. T. M. Ploemen, Willem G.E.J. Schoonen, Pieter Zandberg, Cathelijne P. A. M. Kloks, Jack T. W. E. Vogels, Albert C. Tas, Jan-Remt Mellema, Joop H. J. van Nesselrooij, Carol Thijssen-vanZuylen
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 98(1)
A procedure of nuclear magnetic resonance (NMR) urinalysis using pattern recognition is proposed for early detection of toxicity of investigational compounds in rats. The method is applied to detect toxicity upon administration of 13 toxic reference
Autor:
Daniel J. Lips, E. Delvaux, Fawzi A. Babiker, Pieter Zandberg, Christian Grohé, G.J.J.M. van Eys, Pieter A. Doevendans, Frits W. Prinzen, Ben J. A. Janssen
Publikováno v:
Acta Physiologica. 189
AIM: Observational and clinical studies suggest different responses upon sex hormone replacement therapy in ischaemic heart disease. Few studies, however, have examined the impact of oestrogen receptor-dependent mechanisms on the extent of injury aft
Autor:
Jens Haarbo, Pieter Zandberg, Claus Christiansen, Sven O. Skouby, Peter Alexandersen, Jørgen Jespersen
Publikováno v:
Alexandersen, P, Haarbo, J, Zandberg, P, Jespersen, J, Skouby, S O & Christiansen, C 2003, ' Lack of difference among progestins on the anti-atherogenic effect of ethinyl estradiol : a rabbit study ', Human Reproduction, vol. 18, pp. 1395-1403 .
BACKGROUND Progestins in combination with estrogen are believed to have different effects on the cardiovascular system. The aim of this study was to investigate the influence of different oral contraceptive formulations on the development of experime
Autor:
Pieter Zandberg, Jan L.M. Peters, Pierre N.M. Demacker, Ernst G. de Reeder, Martin J. Smit, Dirk G. Meuleman
Publikováno v:
Menopause (New York, N.Y.). 8(2)
OBJECTIVE: Tibolone is a synthetic steroid with tissue-specific estrogenic, progestogenic, and androgenic properties. The drug relieves climacteric symptoms and prevents osteoporosis but does not stimulate the endometrium. We have previously shown th
Autor:
Pieter Zandberg, Martin J. Smit, Pierre N. M. Demacker, Ernst G. de Reeder, Jan L. M. Peters, D.G. Meuleman
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 18(12)
Abstract —Tibolone (Org OD14), a synthetic steroid with estrogenic and progestogenic/androgenic properties, is clinically effective for the treatment of climacteric symptoms and the prevention and treatment of osteoporosis in postmenopausal women.
Publikováno v:
Toxicology and Applied Pharmacology. 69:37-42
Four nonsteroid anti-inflammatory drugs (NSAID), indomethacin, phenylbutazone, ibuprofen, and glafenine, caused erosions in the rat stomach in a dose-dependent manner. Paracetamol, which has been shown to protect against the gastric erosive activity
Publikováno v:
Agents and actions. 12(1-2)
Indomethacin induced erosions in the glandular part of the rat stomach in a dose-dependent manner. Gastric erosions became apparent about 15 min after administration of indomethacin and the damage was maximal at about 4 h. The erosive activity of ind
Autor:
Willem G. E. J. Schoonen, Cathelijne P. A. M. Kloks, Jan-Peter H. T. M. Ploemen, Martin J. Smit, Pieter Zandberg, G. Jean Horbach, Jan-Remt Mellema, Carol Thijssen-vanZuylen, Albert C. Tas, Joop H. J. van Nesselrooij, Jack T. W. E. Vogels
Publikováno v:
Toxicological Sciences; Jul2007, Vol. 98 Issue 1, p286-286, 1p
Autor:
Willem G. E. J. Schoonen, Cathelijne P. A. M. Kloks, Jan-Peter H. T. M. Ploemen, G. Jean Horbach, Martin J. Smit, Pieter Zandberg, Jan-Remt Mellema, Carol Thijssen-van Zuylen, Albert C. Tas, Joop H. J. van Nesselrooij, Jack T. W. E. Vogels
Publikováno v:
Toxicological Sciences; Jul2007, Vol. 98 Issue 1, p271-271, 1p