Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Piet De Dreu"'
Autor:
Piet de Dreu, Venkataraman Thanabal, J. Richard Miller, Ronald W. Sarver, W. Thomas Mueller, Heather Case, Jeffrey F. Ohren
Publikováno v:
Journal of Bacteriology. 189:8196-8205
Phosphopantetheine adenylyltransferase (PPAT) from Escherichia coli is an essential hexameric enzyme that catalyzes the penultimate step in coenzyme A (CoA) biosynthesis and is a target for antibacterial drug discovery. The enzyme utilizes Mg-ATP and
Autor:
David A. Giegel, Cindy A. Sprecher, Walter Kisiel, Robert R. Annand, John A. Mankovich, Jeffrey R. Dahlen, Donald C. Foster, Piet De Dreu, Robert V. Talanian
Publikováno v:
Biochemical Journal. 342:655-665
The regulation of caspases, cysteine proteinases that cleave their substrates after aspartic residues, is poorly understood, even though they are involved in tightly regulated cellular processes. The recently discovered serpin analogue proteinase inh
Autor:
Jerry L. Hopkins, Piet de Dreu, Mark T. Skoog, Kenneth A. Cohen, Michel J. Emmanuel, Grace C. Chow, Diane Thibeault, Rajashekhar Betageri
Publikováno v:
Journal of biochemical and biophysical methods. 27(3)
The proteinase encoded by human immunodeficiency virus type 1 (HIV-1) cleaves peptide substrates of sequences derived from processing sites in HIV-1 gag-pol polypeptide. Based on this cleavage, assays that utilize HPLC to measure activity of HIV-1 pr