Microfluidic organ-on-a-chip model of the outer blood-retinal barrier with clinically relevant read-outs for tissue permeability and vascular structure

Autor: Carlos Cuartas-Vélez, Sander Logtenberg, Albert van den Berg, Nienke Bosschaart, Joshua Loessberg-Zahl, Wesley Buijsman, Andries D. van der Meer, Anne M Grobbink, Robert Passier, Colin Veenstra, Yusuf B. Arik, Anneke I. den Hollander, Piet Bergveld, Giuliana Gagliardi

Publikováno v: Lab on a Chip, 21, 272-283
Lab on a chip, 21(2), 272-283. Royal Society of Chemistry
Lab on a chip, 2021(2). Royal Society of Chemistry
Lab on a Chip, 21, 2, pp. 272-283

The outer blood–retinal barrier (oBRB) tightly controls the transport processes between the neural tissue of the retina and the underlying blood vessel network. The barrier is formed by the retinal pigment epithelium (RPE), its basal membrane and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1586062a1e5bc4e15ae6ab1692951540
http://hdl.handle.net/2066/230610

Iridium/Anodic Iridium Oxide Film Electrode as a pH Sensor

Autor: N. F. de Rooij, Piet Bergveld

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2b17331f7e941aedd4571c4ebddadb6a
https://doi.org/10.1159/000397278

A hydrogen peroxide sensor for exhaled breath measurement

Autor: Wouter Olthuis, Dam T.V. Anh, Piet Bergveld

Publikováno v: Sensors and actuators. B: Chemical. :494-499

An increase in hydrogen peroxide concentration in exhaled breath (EB) of patients, who suffer from some diseases related to the lung function, has been observed and considered as a reliable indicator of lung diseases. In the EB of these patients, hyd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e03e3a05fd94ad1f25fc031f61f615
https://doi.org/10.1016/j.snb.2005.03.107

A Miniaturized Carbon Dioxide Gas Sensor Based on Sensing of pH-Sensitive Hydrogel Swelling with a Pressure Sensor

Autor: Piet Bergveld, S. Herber, A. van den Berg, Wouter Olthuis, Johan G. Bomer

Publikováno v: Biomedical microdevices, 7(3), 197-204. Kluwer Academic Publishers

A measurement concept has been realized for the detection of carbon dioxide, where the CO(2) induced pressure generation by an enclosed pH-sensitive hydrogel is measured with a micro pressure sensor. The application of the sensor is the quantificatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3070419c8b112c8f18e90923c6a0c0
https://doi.org/10.1007/s10544-005-3026-5

A flow-through potentiometric sensor for an integrated microdialysis system

Autor: A.J. Sprenkels, H.J. van der Linden, Wouter Olthuis, Piet Bergveld, A. van den Berg, Dorota G. Pijanowska

Publikováno v: Sensors and actuators. B: Chemical, 103(1-2), 350-355. Elsevier

In this paper, the performance of a flow-through potentiometric sensor based on a semi-permeable dialysis tubing implemented in silicon, is presented. The sensor is designed as part of a lab-on-a-chip system and has been successfully incorporated int

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99352c7ca16241d78037b66c694fc3e5
https://doi.org/10.1016/j.snb.2004.04.108