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RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells.

Autor: Herrejon Chavez F; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Gerstner Sloan Kettering Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Luo H; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Cifani P; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA., Pine A; Computational Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chu EL; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Pharmacology, Weill Cornell School of Medical Sciences, New York, NY, USA., Joshi S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Barin E; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Pharmacology Program of the Weill Cornell Graduate School of Medicine Sciences, New York, NY, USA., Schurer A; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chan M; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chang K; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Han GYQ; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Pierson AJ; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Xiao M; Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA., Yang X; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kuehm LM; Cell Microsystems, Inc., Durham, NC, USA., Hong Y; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3086, Australia., Nguyen DTT; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, UK., Chiosis G; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kentsis A; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Tow Center for Developmental Oncology, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Departments of Pediatrics, Pharmacology, and Physiology & Biophysics, Weill Medical College of Cornell University, New York, NY, USA., Leslie C; Computational Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Vu LP; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. lvu@bccrc.ca.; Terry Fox Laboratory, British Columbia Cancer Research Centre, Vancouver, BC, Canada. lvu@bccrc.ca.; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada. lvu@bccrc.ca., Kharas MG; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. kharasm@mskcc.org.

Publikováno v: Nature communications [Nat Commun] 2023 Apr 21; Vol. 14 (1), pp. 2290. Date of Electronic Publication: 2023 Apr 21.