Zobrazeno 1 - 10
of 6 951
pro vyhledávání: '"Piersma, A"'
Autor:
Orlane Figaroa, Patricia Zondervan, Rob Kessels, Johannes Berkhof, Maureen Aarts, Paul Hamberg, Maartje Los, Djura Piersma, Bart Rikhof, Britt Suelmann, Metin Tascilar, Astrid van der Veldt, Paul Verhagen, Hans Westgeest, Hilin Yildirim, Axel Bex, Adriaan Bins
Publikováno v:
European Urology Open Science, Vol 70, Iss , Pp 28-35 (2024)
Background: Historically, patients with metastatic renal cell carcinoma (mRCC) have been offered upfront cytoreductive nephrectomy (CN) followed by systemic therapy. Currently, CN is no longer the standard of care (SOC) based on the randomised phase
Externí odkaz:
https://doaj.org/article/35a9cee80bf2492b8d72035a5d3614bb
Publikováno v:
Conservation & Society, 2024 Jan 01. 22(2), 74-85.
Externí odkaz:
https://www.jstor.org/stable/27324014
Autor:
Andrea Vallés‐Martí, Richard R. deGoeij‐de Haas, Alex A. Henneman, Sander R. Piersma, Thang V. Pham, Jaco C. Knol, Joanne Verheij, Frederike Dijk, Hans Halfwerk, Elisa Giovannetti, Connie R. Jiménez, Maarten F. Bijlsma
Publikováno v:
Molecular Oncology, Vol 18, Iss 8, Pp 2020-2041 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with a limited number of known driver mutations but considerable cancer cell heterogeneity. Phosphoproteomics provides a direct read‐out of aberrant signaling and the resultant clinic
Externí odkaz:
https://doaj.org/article/e8ff82023c7546bf9b7c1d4e26f666f5
Autor:
Marta Lopez-Cerda, Laura Lorenzo-Sanz, Victoria da Silva-Diz, Sandra Llop, Rosa M. Penin, Josep Oriol Bermejo, Richard de Goeij-de Haas, Sander R. Piersma, Thang V. Pham, Connie R. Jimenez, Juan Martin-Liberal, Purificación Muñoz
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-21 (2024)
Abstract Background Early cutaneous squamous cell carcinomas (cSCCs) generally show epithelial differentiation features and good prognosis, whereas advanced cSCCs present mesenchymal traits associated with tumor relapse, metastasis, and poor survival
Externí odkaz:
https://doaj.org/article/2d2e3cd7ff3f4fedbed353deaa311a0c
Autor:
Luis Barba-Escoto, Ruth A. Howison, Rienk W. Fokkema, Jean-Yves Duriaux-Chavarría, Marie Stessens, Egbert van der Velde, Jos C.E.W. Hooijmeijer, Theunis Piersma, Pablo A. Tittonell
Publikováno v:
Global Ecology and Conservation, Vol 56, Iss , Pp e03286- (2024)
Agri-environmental schemes (AES) implemented by farmer collectives for meadow bird protection in The Netherlands create complex landscape mosaics due to the variability of options and combinations farmers use. We propose a method to simplify this com
Externí odkaz:
https://doaj.org/article/c38c2cde5e1841b9a77cdc5c7ca5155c
Autor:
Franziska Böttger, Teodora Radonic, Idris Bahce, Kim Monkhorst, Sander R. Piersma, Thang V. Pham, Anne‐Marie C. Dingemans, Lisa M. Hillen, Mariacarmela Santarpia, Elisa Giovannetti, Egbert F. Smit, Sjaak A. Burgers, Connie R. Jimenez
Publikováno v:
Molecular Oncology, Vol 18, Iss 6, Pp 1417-1436 (2024)
The majority of patients with resected stage II‐IIIA non‐small cell lung cancer (NSCLC) are treated with platinum‐based adjuvant chemotherapy (ACT) in a one‐size‐fits‐all approach. However, a significant number of patients do not derive c
Externí odkaz:
https://doaj.org/article/59cc7532a44a481fb7f9c9573d143ffd
Autor:
Changxu Fan, Xiaoyun Xing, Samuel J. H. Murphy, Jennifer Poursine-Laurent, Heather Schmidt, Bijal A. Parikh, Jeesang Yoon, Mayank N. K. Choudhary, Naresha Saligrama, Sytse J. Piersma, Wayne M. Yokoyama, Ting Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Comparative genomics has revealed the rapid expansion of multiple gene families involved in immunity. Members within each gene family often evolved distinct roles in immunity. However, less is known about the evolution of their epigenome and
Externí odkaz:
https://doaj.org/article/2e1544ec47b24a0fa0e54cc35c3f6b85
Publikováno v:
Conservation & Society, Vol 22, Iss 2, Pp 74-85 (2024)
For almost a century, the term ‘flyways’ has been used to order relations over time and space. It has been used to coordinate scientific research and communication as well as monitoring and management efforts for waterbird conservation. In this a
Externí odkaz:
https://doaj.org/article/7dfcf00c95f54466b28281be996cea5a
Autor:
Elisa Suárez-Martínez, Sander R. Piersma, Thang V. Pham, Irene V. Bijnsdorp, Connie R. Jimenez, Amancio Carnero
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Ovarian cancer has a high mortality rate mainly due to its resistance to currently used therapies. This resistance has been associated with the presence of cancer stem cells (CSCs), interactions with the microenvironment, and intr
Externí odkaz:
https://doaj.org/article/af08a23f399f4704a81219517ab21154
Autor:
J. C. Janssen, B. van Dijk, K. de Joode, M. J. B. Aarts, F. W. P. J. van den Berkmortel, C. U. Blank, M. J. Boers-Sonderen, A. J. M. van den Eertwegh, J. W. B. de Groot, M. Jalving, M. J. A. de Jonge, A. Joosse, E. Kapiteijn, A. M. Kamphuis-Huismans, K. A. T. Naipal, D. Piersma, B. Rikhof, H. M. Westgeest, G. Vreugdenhil, E. Oomen-de Hoop, E. E. A. P. Mulder, Astrid A. M. van der Veldt
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Background Patients with irresectable stage III or metastatic melanoma presenting with poor prognostic factors are usually treated with a combination of immune checkpoint inhibitors (ICIs), consisting of ipilimumab and nivolumab. This combin
Externí odkaz:
https://doaj.org/article/ca4c9e5c51fc40759d196932967e286e