Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Piers N. Plowman"'
Autor:
Peter W. Szlosarek, Piers N. Plowman, Simon Pacey, Michael Sheaff, Ramsay S. Khadeir, Dimitris Paraskevopoulos, Kevin O'Neill, Timothy Crook, John S. Bomalaski, Bor-Wen Wu, Kate Smith, Sarah Jefferies, Tomasz Matys, Raj Jena, Fiona P. Harris, Jim A. Thomson, Amanda Johnston, Xiaoxing Feng, Matthew Williams, Stephen Ellis, Jane Evanson, Richard Shaffer, Nelofer Syed, Rachel Lewis, Peter E. Hall
Effects of ADI-PEG20 on the folate pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2483bde836dfd2025bff2a83268065e1
https://doi.org/10.1158/1078-0432.22474215.v1
https://doi.org/10.1158/1078-0432.22474215.v1
Autor:
Peter W. Szlosarek, Piers N. Plowman, Simon Pacey, Michael Sheaff, Ramsay S. Khadeir, Dimitris Paraskevopoulos, Kevin O'Neill, Timothy Crook, John S. Bomalaski, Bor-Wen Wu, Kate Smith, Sarah Jefferies, Tomasz Matys, Raj Jena, Fiona P. Harris, Jim A. Thomson, Amanda Johnston, Xiaoxing Feng, Matthew Williams, Stephen Ellis, Jane Evanson, Richard Shaffer, Nelofer Syed, Rachel Lewis, Peter E. Hall
Kaplan Meier plots for PFS and OS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef26ecccb021317c792c07b8e0484de
https://doi.org/10.1158/1078-0432.22474218
https://doi.org/10.1158/1078-0432.22474218
Autor:
Peter W. Szlosarek, Piers N. Plowman, Simon Pacey, Michael Sheaff, Ramsay S. Khadeir, Dimitris Paraskevopoulos, Kevin O'Neill, Timothy Crook, John S. Bomalaski, Bor-Wen Wu, Kate Smith, Sarah Jefferies, Tomasz Matys, Raj Jena, Fiona P. Harris, Jim A. Thomson, Amanda Johnston, Xiaoxing Feng, Matthew Williams, Stephen Ellis, Jane Evanson, Richard Shaffer, Nelofer Syed, Rachel Lewis, Peter E. Hall
Purpose:Patients with recurrent high-grade gliomas (HGG) are usually managed with alkylating chemotherapy ± bevacizumab. However, prognosis remains very poor. Preclinically, we showed that HGGs are a target for arginine depletion with pegargiminase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e3fc5abb0564f3b74b578495cb2833
https://doi.org/10.1158/1078-0432.c.6528723.v1
https://doi.org/10.1158/1078-0432.c.6528723.v1
Autor:
Peter W. Szlosarek, Piers N. Plowman, Simon Pacey, Michael Sheaff, Ramsay S. Khadeir, Dimitris Paraskevopoulos, Kevin O'Neill, Timothy Crook, John S. Bomalaski, Bor-Wen Wu, Kate Smith, Sarah Jefferies, Tomasz Matys, Raj Jena, Fiona P. Harris, Jim A. Thomson, Amanda Johnston, Xiaoxing Feng, Matthew Williams, Stephen Ellis, Jane Evanson, Richard Shaffer, Nelofer Syed, Rachel Lewis, Peter E. Hall
ASS1 immunohistochemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d4a1ef102aac476b60c41d97b0eb95
https://doi.org/10.1158/1078-0432.22474221.v1
https://doi.org/10.1158/1078-0432.22474221.v1
Autor:
Christopher N. Parris, Helen A. Foster, Hussein Al-Ali, Emma C. Bourton, Sheba Adam-Zahir, Piers N. Plowman
Bacground: Drugs that induce DNA interstrand crosslinks form the mainstay of anticancer treatments for different cancers. These drugs are used to treat ovarian cancer which is the most prevalent gynaecological cancer. Five-year survival rates are app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e96cd3f1087b6d2146d33aeec172ff6
https://doi.org/10.21203/rs.3.rs-667572/v1
https://doi.org/10.21203/rs.3.rs-667572/v1
Autor:
Aparna Pal, Pratistha Panday, Rachel Lewis, Desiree Seguna, Antonia Brooke, William Drake, Jane Evanson, James Ahlquist, Scott Akker, Piers N. Plowman
Publikováno v:
Neuro Oncol
Aims Objective: Active acromegaly is associated with increased mortality. While surgery is the mainstay of treatment, it is not always curative. In selected cases, CyberKnife stereotactic radiosurgery (CK SRS) can be used as adjuvant treatment in pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb5fa2a6cb4f31a254d9142a1eb2ad4b
https://doi.org/10.1093/neuonc/noab195.035
https://doi.org/10.1093/neuonc/noab195.035
Autor:
Philip D. Walson, Philipp Kanzow, Ekkehard Schütz, Michael Oellerich, Julia Beck, Piers N. Plowman, Glen J. Weiss
Publikováno v:
Critical Reviews in Clinical Laboratory Sciences. 54:205-218
High-quality genomic analysis is critical for personalized pharmacotherapy in patients with cancer. Tumor-specific genomic alterations can be identified in cell-free DNA (cfDNA) from patient blood samples and can complement biopsies for real-time mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5eac79efc61f664575fd6ef5ca14392
https://doi.org/10.1080/10408363.2017.1299683
https://doi.org/10.1080/10408363.2017.1299683
Autor:
Marianne Shawe-Taylor, Rachel Lewis, Hannah Lowe, Piers N. Plowman, Lorna Raymond, Karim Keshwani
Publikováno v:
Journal of Clinical Oncology. 38:e14522-e14522
e14522 Background: Corticosteroids are commonly used in neuro-oncology both in the perioperative setting and with chemotherapy and radiotherapy to manage cancer and treatment-associated cerebral oedema and neurological deficits. Corticosteroids are a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a988b9a8652c5c7cd23d6c2f0eae3a28
https://doi.org/10.1200/jco.2020.38.15_suppl.e14522
https://doi.org/10.1200/jco.2020.38.15_suppl.e14522
Autor:
Sheba Adam Zahir, Hussein Al-Ali, Christopher Parris, Pia-Amata Ahorner, Piers N. Plowman, Emma C. Bourton
Publikováno v:
Journal of Cancer
The use of polyADPribose polymerase inhibitors in cancer treatment provides a unique opportunity to target DNA repair processes in cancer cells while leaving normal tissue intact. The PARP-1 enzyme repairs DNA single strand breaks (SSB). Therefore PA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f594ad33ce0b8dde53260a4e2ae3714e
http://bura.brunel.ac.uk/handle/2438/18850
http://bura.brunel.ac.uk/handle/2438/18850
Autor:
Hesham Elhalawani, Massoud Houshmand, Evandro Leite de Souza, Christopher N. Parris, Ao Liu, Eiji Sunami, Toshiaki Tanaka, Hu Zhu, Fatemeh Ahmadipour, Hiroaki Nozawa, Robin I. Taleb, Adriano Zangrandi, Yusuke Shinoda, Helena Tainá D. Silva, Satz Mengensatzproduktion, Alexander Tuan Falk, Yuejun Liu, Wanlong Zhou, Takeshi Nishikawa, Aline Guillot, Depei Wu, Rami Archid, Inmaculada Alés-Díaz, Eleni Nioti, Ioannis Starakis, Patrizia Mordenti, Michaela Tonder, Jürgen Weinreich, Patrizia Farina, Takeshi Hisada, Anastasia Kostaki, Anita Nasrallah, Noriaki Sunaga, Nicolas Magné, Elpis Mantadakis, Anita Hack, Suellen Maria P. Menezes-Silva, Isis Caroline da Silva Cirino, Masanobu Yamada, Costantine F. Daher, Hironori Yamaguchi, Patrick Roth, Perla Zgheib, Masahiko Motegi, Junichiro Tanaka, Hideomi Yamashita, Sofia Maraki, Michael Weller, Kyoichi Kaira, Vittorina Zagonel, Druckerei Stückle, Alfred Königsrainer, Luigi Cavanna, Behnam Kamalidehghan, Akira Honda, Yaoyao Shen, Hirotaka Kawano, Olivier Collard, Cécile Pacaut, Omar Abdel-Rahman, Toshiaki Watanabe, Hisao Imai, Shinsuke Kazama, Guillaume Moriceau, Kazushige Kawai, José P. Siqueira-Júnior, Giuseppe Lombardi, Shiwei Sun, Mineo Kurokawa, Elena Orlandi, Goh Yong Meng, Jane-Chloé Trone, Günter Eisele, Piers N. Plowman, Ana Maria Galeote-Miguel, Jia Chen, Khaled Bajaeifer, Alessandra Ferro, Tomomichi Kiyomatsu, George Samonis, Angelos Koutras, Ichiro Naruse, Hui Li, Mirvat El-Sibai, Sheba Adam-Zahir, Takashi Toya, Benoite Méry, Joji Kitayama, Tetsuo Ushiku, Yasunori Kogure, Keisuke Hata, Fable Zustovich, Yasuhito Nannya, Gema Durán-Ogalla, Mohamad Mroueh, Soichiro Ishihara, Manuel Benavides-Orgaz, Luis Enrique Rodelo-Haad, Akihide Yoshimi, Minas Sakellakis, Fariha Sharif, Reyhaneh Shakibi, Takayuki Asao, Haruki Kume, Timm C. Schott, Maria José Bermejo-Pérez, Emma C. Bourton
Publikováno v:
Chemotherapy. 60:I-IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::225e9b6b5f2e62f7bf4ce3d5de29ebe8
https://doi.org/10.1159/000440657
https://doi.org/10.1159/000440657