Chromosomal assembly of the flat oyster (Ostrea edulis L.) genome as a new genetic resource for aquaculture

Autor: Isabelle Boutet, Homère J. Alves Monteiro, Lyam Baudry, Takeshi Takeuchi, Eric Bonnivard, Bernard Billoud, Sarah Farhat, Ricardo Gonzales‐Araya, Benoit Salaun, Ann C. Andersen, Jean‐Yves Toullec, François H. Lallier, Jean‐François Flot, Nadège Guiglielmoni, Ximing Guo, Cui Li, Bassem Allam, Emmanuelle Pales‐Espinosa, Jakob Hemmer‐Hansen, Pierrick Moreau, Martial Marbouty, Romain Koszul, Arnaud Tanguy

Publikováno v: Evolutionary Applications, Vol 15, Iss 11, Pp 1730-1748 (2022)

Abstract The European flat oyster (Ostrea edulis L.) is a native bivalve of the European coasts. Harvest of this species has declined during the last decades because of the appearance of two parasites that have led to the collapse of the stocks and t

Externí odkaz: https://doaj.org/article/b51c868830854eed9e0f112bd5a54b2d

Tridimensional infiltration of DNA viruses into the host genome shows preferential contact with active chromatin

Autor: Pierrick Moreau, Axel Cournac, Gianna Aurora Palumbo, Martial Marbouty, Shogofa Mortaza, Agnes Thierry, Stefano Cairo, Marc Lavigne, Romain Koszul, Christine Neuveut

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)

Whether DNA viruses contact specific regions of host genomes or make random contacts is unclear. Here, the authors use Hi-C and show that HBV cccDNA and Ad5 DNA contact preferentially active chromatin at CpG islands for the former and at transcriptio

Externí odkaz: https://doaj.org/article/878cd31675d7462e94de500ad5635813

Normalization of Chromosome Contact Maps: Matrix Balancing and Visualization

Autor: Romain Koszul, Pierrick Moreau, Axel Cournac, Shogofa Mortaza, Lyam Baudry, Cyril Matthey-Doret

Publikováno v: Hi-C Data Analysis : methods and protocols
Silvio Bicciato, Francesco Ferrari. Hi-C Data Analysis : methods and protocols, 2301, Springer US, pp.1-15, 2022, Methods in Molecular Biology, 978-1-0716-1390-0 (ebook). ⟨10.1007/978-1-0716-1390-0_1⟩
Methods in Molecular Biology ISBN: 9781071613894

International audience; Over the last decade, genomic proximity ligation approaches have reshaped our vision of chromosomes 3D organizations, from bacteria nucleoids to larger eukaryotic genomes. The different protocols (3Cseq, Hi-C, TCC, MicroC [XL]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d1c8acd05a0d419692435cb07d5c7f
https://hal-pasteur.archives-ouvertes.fr/pasteur-03376844

Pesticides and Ostreid Herpesvirus 1 Infection in the Pacific Oyster, Crassostrea gigas.

Autor: Pierrick Moreau, Nicole Faury, Thierry Burgeot, Tristan Renault

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0130628 (2015)

Since 2008, mass mortality outbreaks have been reported in all French regions producing Pacific oysters, and in several Member States of the European Union. These mass mortality events of Pacific oysters are related to OsHV-1 infection. They occur du

Externí odkaz: https://doaj.org/article/83f4754c143e4cf59e23e8e7a17d0ee3

Computer vision for pattern detection in chromosome contact maps

Autor: Axel Breuer, Axel Cournac, Antoine Vigouroux, Etienne Jean, Adrien Meot, Edgar Oriol, Romain Koszul, Laurent Politis, Arnaud Campeas, Nadège Guiglielmoni, Cyril Matthey-Doret, Lyam Baudry, Vittore F. Scolari, Philippe Henri Chanut, Pierrick Moreau, Rémi Montagne

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.5795. ⟨10.1038/s41467-020-19562-7⟩
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications, 2020, 11 (1), pp.5795. ⟨10.1038/s41467-020-19562-7⟩

Chromosomes of all species studied so far display a variety of higher-order organisational features, such as self-interacting domains or loops. These structures, which are often associated to biological functions, form distinct, visible patterns on g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29132112413e0410fbf43fcd2cafa573
https://doi.org/10.1038/s41467-020-19562-7