Zobrazeno 1 - 10
of 379
pro vyhledávání: '"Pierrick, Bourgeat"'
Autor:
Léonie Borne, Renate Thienel, Michelle K. Lupton, Christine Guo, Philip Mosley, Anna Behler, Joseph Giorgio, Robert Adam, Amelia Ceslis, Pierrick Bourgeat, Amir Fazlollahi, Paul Maruff, Christopher C. Rowe, Colin L. Masters, Jurgen Fripp, Gail A. Robinson, Michael Breakspear
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Deficits in memory are seen as a canonical sign of aging and a prodrome to dementia in older adults. However, our understanding of age-related cognition and brain morphology occurring throughout a broader spectrum of adulthood remains limite
Externí odkaz:
https://doaj.org/article/a7e8d0a960f341259f3bfca57dd0ef4d
Autor:
Azadeh Feizpour, James David Doecke, Vincent Doré, Natasha Krishnadas, Kun Huang, Pierrick Bourgeat, Simon Matthew Laws, Christopher Fowler, Joanne Robertson, Lucy Mackintosh, Scott Ayton, Ralph Martins, Stephanie Ruth Rainey-Smith, Kevin Taddei, Larry Ward, Eddie Stage, Anthony Wilson Bannon, Colin Louis Masters, Jurgen Fripp, Victor Luis Villemagne, Christopher Cleon Rowe
Publikováno v:
EBioMedicine, Vol 109, Iss , Pp 105405- (2024)
Summary: Background: Plasma phospho-tau 217 (pTau217) assays can accurately detect Alzheimer's disease (AD) pathology, but clinical application is limited by the need for specialised equipment. This study tests the performance of a plasma pTau217 ass
Externí odkaz:
https://doaj.org/article/5b388413e0784c49a4221b9a0b49897b
Autor:
Yi‐En Quek, Yi Leng Fung, Pierrick Bourgeat, Simon J. Vogrin, Steven J. Collins, Stephen C. Bowden
Publikováno v:
Brain and Behavior, Vol 14, Iss 5, Pp n/a-n/a (2024)
Abstract Introduction The current study examined the contributions of comprehensive neuropsychological assessment and volumetric assessment of selected mesial temporal subregions on structural magnetic resonance imaging (MRI) to identify patients wit
Externí odkaz:
https://doaj.org/article/10f0823dda2d40129bb7f999f45e3fe4
Autor:
Ariane Bollack, Pawel J Markiewicz, Alle Meije Wink, Lloyd Prosser, Johan Lilja, Pierrick Bourgeat, Jonathan M Schott, William Coath, Lyduine E Collij, Hugh G Pemberton, Gill Farrar, Frederik Barkhof, David M Cash
Publikováno v:
NeuroImage, Vol 280, Iss , Pp 120313- (2023)
Purpose: Positron emission tomography (PET) provides in vivo quantification of amyloid-β (Aβ) pathology. Established methods for assessing Aβ burden can be affected by physiological and technical factors. Novel, data-driven metrics have been devel
Externí odkaz:
https://doaj.org/article/31a4b313a057412299854b162b868a65
Autor:
Martin Saint-Jalmes, Victor Fedyashov, Daniel Beck, Timothy Baldwin, Noel G. Faux, Pierrick Bourgeat, Jurgen Fripp, Colin L. Masters, Benjamin Goudey
Publikováno v:
NeuroImage, Vol 278, Iss , Pp 120279- (2023)
The recent biological redefinition of Alzheimer’s Disease (AD) has spurred the development of statistical models that relate changes in biomarkers with neurodegeneration and worsening condition linked to AD. The ability to measure such changes may
Externí odkaz:
https://doaj.org/article/d10a253954e547b699e2b2e6b86c3995
Autor:
Pierrick Bourgeat, Vincent Doré, Christopher C. Rowe, Tammie Benzinger, Duygu Tosun, Manu S. Goyal, Pamela LaMontagne, Liang Jin, Michael W. Weiner, Colin L. Masters, Jurgen Fripp, Victor L. Villemagne, for the Alzheimer's Disease Neuroimaging Initiative, OASIS3, and the AIBL research group
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 3, Pp n/a-n/a (2023)
Abstract INTRODUCTION The Centiloid (CL) project was developed to harmonize the quantification of amyloid beta (Aβ) positron emission tomography (PET) scans to a unified scale. The CL neocortical mask was defined using 11C Pittsburgh compound B (PiB
Externí odkaz:
https://doaj.org/article/5776b4bca24f437f806ac7c5e2774184
Autor:
Victor L. Villemagne, Antoine Leuzy, Sandra Sanabria Bohorquez, Santiago Bullich, Hitoshi Shimada, Christopher C. Rowe, Pierrick Bourgeat, Brian Lopresti, Kun Huang, Natasha Krishnadas, Jurgen Fripp, Yuhei Takado, Alexandra Gogola, Davneet Minhas, Robby Weimer, Makoto Higuchi, Andrew Stephens, Oskar Hansson, Vincent Doré, Alzheimer's Disease Neuroimaging Initiative and the AIBL research group
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 3, Pp n/a-n/a (2023)
Abstract INTRODUCTION Recently, an increasing number of tau tracers have become available. There is a need to standardize quantitative tau measures across tracers, supporting a universal scale. We developed several cortical tau masks and applied them
Externí odkaz:
https://doaj.org/article/e3a442eac9e64af3bc0f3fc0565a03c8
Autor:
Michael Vacher, Vincent Doré, Tenielle Porter, Lidija Milicic, Victor L. Villemagne, Pierrick Bourgeat, Sam C. Burnham, Timothy Cox, Colin L. Masters, Christopher C. Rowe, Jurgen Fripp, James D. Doecke, Simon M. Laws
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-8 (2022)
Abstract Background With a growing number of loci associated with late-onset (sporadic) Alzheimer’s disease (AD), the polygenic contribution to AD is now well established. The development of polygenic risk score approaches have shown promising resu
Externí odkaz:
https://doaj.org/article/922fd30cfa5d4aa2bb78f823a53ae0a8
Autor:
Natasha Krishnadas, Vincent Doré, Colin Groot, Fiona Lamb, Pierrick Bourgeat, Samantha C. Burnham, Kun Huang, Anita M. Y. Goh, Colin L. Masters, Victor L. Villemagne, Christopher C. Rowe, for the AIBL research group
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-10 (2022)
Abstract Background Tau deposition in the mesial temporal lobe (MTL) in the absence of amyloid-β (Aβ−) occurs with aging. The tau PET tracer 18F-MK6240 has low non-specific background binding so is well suited to exploration of early-stage tau de
Externí odkaz:
https://doaj.org/article/29865099cabe401bb295621f4d6488e7
Autor:
Caterina Brighi, Simon Puttick, Shenpeng Li, Paul Keall, Katherine Neville, David Waddington, Pierrick Bourgeat, Ashley Gillman, Michael Fay
Publikováno v:
EJNMMI Physics, Vol 9, Iss 1, Pp 1-13 (2022)
Abstract Background Multicentre clinical trials evaluating the role of 18F-Fluoroethyl-l-tyrosine (18F-FET) PET as a diagnostic biomarker in glioma management have highlighted a need for standardised methods of data analysis. 18F-FET uptake normalise
Externí odkaz:
https://doaj.org/article/7941e84eedcb4ced90e7106dd1f77bd3