Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Pierre-yves Renard"'
Autor:
Maxime Patout, Florian Guisier, Xavier Brune, Pierre Bohn, Anthony Romieu, Nasrin Sarafan-Vasseur, Richard Sesboüé, Pierre-Yves Renard, Luc Thiberville, Mathieu Salaün
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background EGFR mutations are routinely explored in lung adenocarcinoma by sequencing tumoral DNA. The aim of this study was to evaluate a fluorescent-labelled erlotinib based theranostic agent for the molecular imaging of mutated EGFR tumou
Externí odkaz:
https://doaj.org/article/c2992972b3fb4d9a8bfe21bb646f20da
Autor:
Victor Flon, Magalie Bénard, Damien Schapman, Ludovic Galas, Pierre-Yves Renard, Cyrille Sabot
Publikováno v:
Biomolecules, Vol 10, Iss 4, p 619 (2020)
The copper-catalyzed alkyne-azide cycloaddition (CuAAC) is one of the most powerful chemical strategies for selective fluorescent labeling of biomolecules in in vitro or biological systems. In order to accelerate the ligation process and ensure effic
Externí odkaz:
https://doaj.org/article/40bc59c05ab8468c8183f839a0130f97
Autor:
Mégane Pons, Ludovic Jean, Sylvain Routier, Frédéric Buron, Sylvie Chalon, Pierre-Yves Renard
Publikováno v:
Proceedings, Vol 22, Iss 1, p 88 (2019)
Alzheimer’s disease (AD) is a complex and progressive neurodegenerative disorder. The available therapy is limited to symptomatic treatment, and its efficacy remains unsatisfactory. In view of the prevalence and expected increase in the incidence o
Externí odkaz:
https://doaj.org/article/7aa0458ce722468585e13d8143bf8117
Autor:
Carles Galdeano, Nicolas Coquelle, Monika Cieslikiewicz-Bouet, Manuela Bartolini, Belén Pérez, M. Victòria Clos, Israel Silman, Ludovic Jean, Jacques-Philippe Colletier, Pierre-Yves Renard, Diego Muñoz-Torrero
Publikováno v:
Molecules, Vol 23, Iss 3, p 634 (2018)
Symptomatic treatment of myasthenia gravis is based on the use of peripherally-acting acetylcholinesterase (AChE) inhibitors that, in some cases, must be discontinued due to the occurrence of a number of side-effects. Thus, new AChE inhibitors are be
Externí odkaz:
https://doaj.org/article/efec3239150e44f5a5e1fd2374d6eefb
Publikováno v:
European Journal of Organic Chemistry. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85034ee41cc7b847aef272a53b694e3b
https://doi.org/10.1002/ejoc.202201401
https://doi.org/10.1002/ejoc.202201401
Autor:
Ophélie Da Silva, Nicolas Probst, Christophe Landry, Anne-Sophie Hanak, Pierre Warnault, Caroline Coisne, André-Guilhem Calas, Fabien Gosselet, Charlotte Courageux, Anne-Julie Gastellier, Marilène Trancart, Rachid Baati, Marie-Pierre Dehouck, Ludovic Jean, Florian Nachon, Pierre-Yves Renard, José Dias
Publikováno v:
Journal of medicinal chemistry. 65(6)
Recent events demonstrated that organophosphorus nerve agents are a serious threat for civilian and military populations. The current therapy includes a pyridinium aldoxime reactivator to restore the enzymatic activity of acetylcholinesterase located
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b10be7299966ca431e030bdf7e62d4
https://pubmed.ncbi.nlm.nih.gov/35255209
https://pubmed.ncbi.nlm.nih.gov/35255209
Publikováno v:
European Journal of Organic Chemistry. 2022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f946f25c6fce062a0ed4bb0a93083eae
https://doi.org/10.1002/ejoc.202201314
https://doi.org/10.1002/ejoc.202201314
Autor:
Alexis Lossouarn, Chloé Puteaux, Laetitia Bailly, Vincent Tognetti, Laurent Joubert, Pierre‐Yves Renard, Cyrille Sabot
Publikováno v:
Chemistry – A European Journal. 28
Proteins are able to irreversibly assemble biologically active ligands from building blocks bearing complementary reactive functions due their spatial proximity, through a kinetic target-guided synthetic process (also named in situ click chemistry).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a946e8bd5324adb2b830e8c16c91ea7d
https://doi.org/10.1002/chem.202202180
https://doi.org/10.1002/chem.202202180
Autor:
Amélie Claudel, Pierre-Yves Renard, Julien Legros, Baptiste Picard, Léa Sigot, Cécile Vallières, Antonin Delaune, Sergui Mansour, Maxime Manneveau
Publikováno v:
Green Chemistry
Green Chemistry, Royal Society of Chemistry, 2021, pp.7522-7527. ⟨10.1039/D1GC01961A⟩
Green Chemistry, Royal Society of Chemistry, 2021, pp.7522-7527. ⟨10.1039/D1GC01961A⟩
International audience; The neutralisation of a simulant of the chemical warfare agent VX (PhX) occurs selectively with lithium ethanolate under classic flow conditions but with moderate reproducibility. Transposed in a custom printed flow reactor, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::631945ca3d36cf51b3ae1f587cd81961
https://hal.archives-ouvertes.fr/hal-03353830
https://hal.archives-ouvertes.fr/hal-03353830
Publikováno v:
European Journal of Organic Chemistry. 2019:3134-3141
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::240e9f145869a0ad79f53f19842aabb4
https://doi.org/10.1002/ejoc.201900378
https://doi.org/10.1002/ejoc.201900378