Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Pierre-Olivier Tremblay"'
Autor:
Nassim Djebli, Pierre-Olivier Tremblay, Vincent Buchheit, Mario González-Sales, Guillaume Bonnefois, Georgina Meneses-Lorente, Francois Mercier, Nicolas Frey
Publikováno v:
Cancer Chemotherapy and Pharmacology. 88:997-1007
Entrectinib (ROZLYTREK®) is a CNS-active, potent, and selective inhibitor of ROS1, TRK A/B/C, and ALK kinase activity. It was recently approved for the treatment of ROS1-positive non-small cell lung cancer and NTRK gene fusion-positive solid tumors.
Publikováno v:
Chaos (Woodbury, N.Y.). 31(2)
Quantitative systems pharmacology (QSP) proved to be a powerful tool to elucidate the underlying pathophysiological complexity that is intensified by the biological variability and overlapped by the level of sophistication of drug dosing regimens. Th
Autor:
Pierre-Olivier Tremblay
Publikováno v:
Pèlerinage, marche pèlerine et marche de longue durée au Québec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b05bce551f557e9d9a771669dd35c4e5
https://doi.org/10.2307/j.ctv1hcg0kw.17
https://doi.org/10.2307/j.ctv1hcg0kw.17
Publikováno v:
British Journal of Clinical Pharmacology. 83:1240-1251
Aims The aim of this paper is to investigate the role of drug concentration samplings in the modelling of the dose-response relationship. Methods Using an initial PK/PD model, a reference dataset was simulated. PK and PD samples were extracted to cre
Modeling Testosterone Circadian Rhythm in Hypogonadal Males: Effect of Age and Circannual Variations
Autor:
Olivier Barrière, Mario Tanguay, Julie Desrochers, Fahima Nekka, Pierre-Olivier Tremblay, Mario González-Sales
Publikováno v:
The AAPS Journal
The objective of this study was to characterize the baseline circadian rhythm of testosterone levels in hypogonadal men. A total of 859 baseline profiles of testosterone from hypogonadal men were included in this analysis. The circadian rhythm of the
Autor:
Mario González-Sales, Pierre Olivier Tremblay, Guillaume Bonnefois, Fahima Nekka, Olivier Barrière, Julie Desrochers
Publikováno v:
The R Journal. 12:107
Autor:
Vincent Pichette, Olivier Barrière, Pierre-Olivier Tremblay, Raphaël Vlavonou, Mario Tanguay, Eric Shink, Richard Larouche, Marc M. Perreault
Publikováno v:
The Journal of Clinical Pharmacology. 54:584-592
The pharmacokinetics of baclofen is well delineated in subjects with normal kidney function (KF); however, pharmacokinetics data in patients with chronic kidney disease (CKD) are not and dosage recommendations remain empirical. The effects of CKD on
Publikováno v:
Gestion. 35:56-63
La creativite constitue pour l’organisation une source de valeur ajoutee, de performance et de competitivite. Cela dit, que peut faire l’organisation pour ameliorer la creativite de son personnel? Quels mecanismes peut-elle mettre en place? Comme
Autor:
Mario Tanguay, Fahima Nekka, Jean-Claude Mamputu, Olivier Barrière, Sylvie Boudreault, Pierre Olivier Tremblay, Mario González-Sales
Publikováno v:
Journal of pharmacokinetics and pharmacodynamics. 42(3)
The objective of this analysis was to characterize the time course of selected pharmacodynamic (PD) markers of tesamorelin: growth hormone (GH) and insulin-like growth factor (IGF-1) concentrations in HIV-infected patients and healthy volunteers. A t
Autor:
Sylvie Boudreault, Jean-Claude Mamputu, Olivier Barrière, Mario Tanguay, Pierre Olivier Tremblay, Mario González-Sales, Fahima Nekka
Publikováno v:
Clinical pharmacokinetics. 54(3)
Tesamorelin is a synthetic analogue of growth hormone-releasing factor (GRF), which increases basal and pulsatile growth hormone (GH) secretion and subsequently increases insulin-like growth factor (IGF)-1. Limited information is available about the