Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Pierre-Louis Hollier"'
Autor:
Dáire Healy, Carol Murray, Ciara McAdams, Ruth Power, Pierre-Louis Hollier, Jessica Lambe, Lucas Tortorelli, Ana Belen Lopez-Rodriguez, Colm Cunningham
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Age is a significant but heterogeneous risk factor for acute neuropsychiatric disturbances such as delirium. Neuroinflammation increases with aging but the determinants of underlying risk for acute dysfunction upon systemic inflammation are
Externí odkaz:
https://doaj.org/article/dbbe9cf39cdb4d48b2927ea08635a332
Autor:
Pierre Mora, Pierre-Louis Hollier, Sarah Guimbal, Alice Abelanet, Aïssata Diop, Lauriane Cornuault, Thierry Couffinhal, Sam Horng, Alain-Pierre Gadeau, Marie-Ange Renault, Candice Chapouly
Publikováno v:
PLoS Biology, Vol 18, Iss 11, p e3000946 (2020)
Inflammation of the central nervous system (CNS) induces endothelial blood-brain barrier (BBB) opening as well as the formation of a tight junction barrier between reactive astrocytes at the Glia Limitans. We hypothesized that the CNS parenchyma may
Externí odkaz:
https://doaj.org/article/f22af7aab48e42ed8e9e3e006091fd2e
Autor:
Lauriane Cornuault, Thierry Couffinhal, Alain-Pierre Gadeau, Paul Rouault, Marie-Lise Bats, Marie-Ange Renault, Julien Imbault, Sarah Guimbal, Candice Chapouly, Pierre-Louis Hollier
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, 2021, Online ahead of print. ⟨10.1161/ATVBAHA.121.315900⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2021, Online ahead of print. ⟨10.1161/ATVBAHA.121.315900⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, 2021, Online ahead of print. ⟨10.1161/ATVBAHA.121.315900⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2021, Online ahead of print. ⟨10.1161/ATVBAHA.121.315900⟩
Objective: Heart failure with preserved ejection fraction is a major health care issue which has been difficult to manage to date, due to its complex and not well understood pathophysiology. Specifically, if a wealth of literature focuses on heart fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5aaae18a47c8baccab785fa1034a9c
https://pubmed.ncbi.nlm.nih.gov/33760636
https://pubmed.ncbi.nlm.nih.gov/33760636
Autor:
Alain-Pierre Gadeau, Sarah Guimbal, Marie-Ange Renault, Candice Chapouly, Lauriane Cornuault, Pierre-Louis Hollier
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2020, ATVBAHA120314441, Online ahead of print. ⟨10.1161/ATVBAHA.120.314441⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, ATVBAHA120314441, Online ahead of print. ⟨10.1161/ATVBAHA.120.314441⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, American Heart Association, 2020, ATVBAHA120314441, Online ahead of print. ⟨10.1161/ATVBAHA.120.314441⟩
Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, ATVBAHA120314441, Online ahead of print. ⟨10.1161/ATVBAHA.120.314441⟩
Objective: Evidences accumulated within the past decades identified hedgehog signaling as a new regulator of endothelium integrity. More specifically, we recently identified Dhh (desert hedgehog) as a downstream effector of Klf2 (Kruppel-like factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b70093475c40adaae0914934c30ff32
https://www.hal.inserm.fr/inserm-02983021
https://www.hal.inserm.fr/inserm-02983021
Autor:
Lauriane Cornuault, Candice Chapouly, Sarah Guimbal, Pierre-Louis Hollier, Thierry Couffinhal, Marie-Lise Bats, Marie-Ange Renault, Alain-Pierre Gadeau
RationalHeart failure with preserved ejection fraction (HFpEF) is a growing epidemiologic issue. However, to date, its pathophysiology remains poorly understood.ObjectiveOur goal was to investigate the role of microvessel disease in the pathophysiolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65fe9d2fe71b5c0ad9ee2d4c37c65b1d
https://doi.org/10.1101/2020.06.16.154872
https://doi.org/10.1101/2020.06.16.154872
Autor:
Candice Chapouly, Marie-Ange Renault, Lauriane Cornuault, Sarah Guimbal, Pierre-Louis Hollier, Alain-Pierre Gadeau
Evidences accumulated within the past decades, identified Hedgehog (Hh) signaling as a new regulator of micro-vessel integrity. More specifically, we recently identified Desert Hedgehog (Dhh) as a downstream effector of Klf2 in endothelial cells (ECs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3195535ed4f484d8f22f330ce8d0445b
https://doi.org/10.1101/2020.04.20.050542
https://doi.org/10.1101/2020.04.20.050542
Autor:
Aïssata Diop, Candice Chapouly, Lauriane Cornuault, Alain-Pierre Gadeau, Marie-Ange Renault, Thierry Couffinhal, Sarah Guimbal, P. Mora, Pierre-Louis Hollier
Recent work demonstrated that Central Nervous System (CNS) inflammation induces endothelial Blood Brain Barrier (BBB) opening as well as the formation of a tight junction barrier between reactive astrocytes at the Glia Limitans. We hypothesized that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc091145daddcc5bfd20b88a826f973d
https://doi.org/10.1101/2020.03.13.990762
https://doi.org/10.1101/2020.03.13.990762
Autor:
Alain-Pierre Gadeau, Aïssata Diop, Sarah Guimbal, Candice Chapouly, Marie-Ange Renault, Pierre-Louis Hollier, Lauriane Cornuault
RationaleThe therapeutic potential of Hedgehog (Hh) signaling agonists for vascular diseases is of growing interest. However, molecular and cellular mechanisms underlying the role of the Hh signaling in vascular biology remain poorly understood.Objec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e419fb060244e1ed154fe8f55db586
https://doi.org/10.1101/2020.03.03.974444
https://doi.org/10.1101/2020.03.03.974444
Autor:
Marie-Ange Renault, Caroline Caradu, Candice Chapouly, Pierre-Louis Hollier, Sarah Guimbal, Alessandra Bura-Rivière, Thierry Couffinhal, Mathilde Dubois, Eric Ducasse, Alain-Pierre Gadeau
Publikováno v:
Circulation Research
Circulation Research, American Heart Association, 2018, 123 (9), pp.1053-1065. ⟨10.1161/CIRCRESAHA.118.313177⟩
Circulation Research, 2018, 123 (9), pp.1053-1065. ⟨10.1161/CIRCRESAHA.118.313177⟩
Circulation Research, American Heart Association, 2018, 123 (9), pp.1053-1065. ⟨10.1161/CIRCRESAHA.118.313177⟩
Circulation Research, 2018, 123 (9), pp.1053-1065. ⟨10.1161/CIRCRESAHA.118.313177⟩
Rationale: Klf (kruppel-like factor) 2 is critical to establish and maintain endothelial integrity. Objective: Therefore, determining upstream and downstream mediators of Klf2 would lead to alternative therapeutic targets in cardiovascular disease ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a772863bb8261c9747d04f7778ce3d
https://doi.org/10.1161/circresaha.118.313177
https://doi.org/10.1161/circresaha.118.313177
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 12, p 3076 (2019)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2019, 20 (12), pp.3076. ⟨10.3390/ijms20123076⟩
International Journal of Molecular Sciences, 2019, 20 (12), pp.3076. ⟨10.3390/ijms20123076⟩
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2019, 20 (12), pp.3076. ⟨10.3390/ijms20123076⟩
International Journal of Molecular Sciences, 2019, 20 (12), pp.3076. ⟨10.3390/ijms20123076⟩
International audience; The role of Hedgehog (Hh) signaling in vascular biology has first been highlighted in embryos by Pepicelli et al. in 1998 and Rowitch et al. in 1999. Since then, the proangiogenic role of the Hh ligands has been confirmed in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f429d60fff5f5dca24fc038033f3ef9f
https://www.mdpi.com/1422-0067/20/12/3076
https://www.mdpi.com/1422-0067/20/12/3076