Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Pierre-François Cartron"'
Autor:
Thierry Gauthier, Omayra Martin-Rodriguez, Cécile Chagué, Anna Daoui, Adam Ceroi, Alexis Varin, Francis Bonnefoy, Séverine Valmary-Degano, Mélanie Couturier, Susanne Behlke, Philippe Saas, Pierre-François Cartron, Sylvain Perruche
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background Reinstating inflammation resolution represents an innovative concept to regain inflammation control in diseases marked by chronic inflammation. While most therapeutics target inflammatory molecules and inflammatory effector cells
Externí odkaz:
https://doaj.org/article/ff55f83d61f749b3983efca034044231
Autor:
Gwenola Bougras-Cartron, Arulraj Nadaradjane, Marie-Pierre Joalland, Lisenn Lalier-Bretaudeau, Judith Raimbourg, Pierre-François Cartron
Publikováno v:
Cancers, Vol 15, Iss 12, p 3188 (2023)
Background: Despite encouraging anti-tumour activity in lung cancer, anti-PD-1 therapy has encountered increasing resistance to treatment. Several companion diagnostic assays have been performed to identify patients who may benefit from this immunoth
Externí odkaz:
https://doaj.org/article/a7691ea35509465bafeddc7a9ede028d
Autor:
Lisenn Lalier, Vincent Mignard, Marie-Pierre Joalland, Didier Lanoé, Pierre-François Cartron, Stéphen Manon, François M. Vallette
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-11 (2021)
Abstract In this work, we have explored the subcellular localization of Bcl2, a major antiapoptotic protein. In U251 glioma cells, we found that Bcl2 is localized mainly in the ER and is translocated to MAM and mitochondria upon induction of apoptosi
Externí odkaz:
https://doaj.org/article/72336e4f9ad24e9291ef2c91af411e5c
Autor:
Joséphine Briand, Aurélien A. Sérandour, Arulraj Nadaradjane, Gwenola Bougras-Cartron, Dominique Heymann, Benjamin Ory, François M. Vallette, Pierre-François Cartron
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 72-83 (2020)
MicroRNAs (miRNAs or miRs) play crucial roles in biological and pathological processes. Some miRNAs also appear as promising biomarkers and therapeutic tools. However, the epitranscriptomic regulation of miRNAs is not yet fully elucidated in all of t
Externí odkaz:
https://doaj.org/article/1923c4a8e922482c889c4a8688391f88
Autor:
Nina Guyon, Delphine Garnier, Joséphine Briand, Arulraj Nadaradjane, Gwenola Bougras-Cartron, Judith Raimbourg, Mario Campone, Dominique Heymann, François M. Vallette, Jean-Sébastien Frenel, Pierre-François Cartron
Publikováno v:
Cell Death and Disease, Vol 11, Iss 12, Pp 1-11 (2020)
Abstract Anti-PD1 immunotherapy, as a single agent or in combination with standard chemotherapies, has significantly improved the outcome of many patients with cancers. However, resistance to anti-PD1 antibodies often decreases the long-term therapeu
Externí odkaz:
https://doaj.org/article/a9df5a188ee4453c9e09d42ff5c0c69d
Autor:
Mathilde Cheray, Amandine Etcheverry, Camille Jacques, Romain Pacaud, Gwenola Bougras-Cartron, Marc Aubry, Florent Denoual, Pierre Peterlongo, Arulraj Nadaradjane, Joséphine Briand, Farida Akcha, Dominique Heymann, François M. Vallette, Jean Mosser, Benjamin Ory, Pierre-François Cartron
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-16 (2020)
Abstract Background Literature reports that mature microRNA (miRNA) can be methylated at adenosine, guanosine and cytosine. However, the molecular mechanisms involved in cytosine methylation of miRNAs have not yet been fully elucidated. Here we inves
Externí odkaz:
https://doaj.org/article/559fa47d8d234bfea3bb4d6081c35783
Autor:
Arulraj Nadaradjane, Joséphine Briand, Gwenola Bougras-Cartron, Valentine Disdero, François M. Vallette, Jean-Sébastien Frenel, Pierre-François Cartron
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 642-650 (2018)
In the last decade, microRNAs (miRs) have been described as biomarkers and therapeutic agents. Based on this finding, our aim here is to know if (1) miRNA-370-3p can be used as a biomarker associated with a favorable survival and if (2) miRNA-370-3p
Externí odkaz:
https://doaj.org/article/7362bc54b37f4aadb1a5de236436990f
Autor:
Delphine Garnier, Edward Ratcliffe, Joséphine Briand, Pierre-François Cartron, Lisa Oliver, François M. Vallette
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 112 (2022)
Glioblastoma (GBM) is the most aggressive brain tumor, and despite initial response to chemo- and radio-therapy, the persistence of glioblastoma stem cells (GSCs) unfortunately always results in tumor recurrence. It is now largely admitted that tumor
Externí odkaz:
https://doaj.org/article/593e3dceeac64b9eb9218f73ea9568b4
Autor:
Eric Hervouet, Paul Peixoto, Régis Delage-Mourroux, Michaël Boyer-Guittaut, Pierre-François Cartron
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-18 (2018)
Abstract Our current view of DNA methylation processes is strongly moving: First, even if it was generally admitted that DNMT3A and DNMT3B are associated with de novo methylation and DNMT1 is associated with inheritance DNA methylation, these distinc
Externí odkaz:
https://doaj.org/article/659bf506ec314a798b34729bce22b464
Autor:
Manon Duforestel, Arulraj Nadaradjane, Gwenola Bougras-Cartron, Joséphine Briand, Christophe Olivier, Jean-Sébastien Frenel, François M. Vallette, Sophie A. Lelièvre, Pierre-François Cartron
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
The acknowledgment that pollutants might influence the epigenome raises serious concerns regarding their long-term impact on the development of chronic diseases. The herbicide glyphosate has been scrutinized for an impact on cancer incidence, but rep
Externí odkaz:
https://doaj.org/article/f00f1fca75874703aa8080106019d370