Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Pierre-Alain Boyer"'
Publikováno v:
Behavioural Pharmacology. 17:703-713
To confirm the antidepressant-like activity of agomelatine (S 20098), a melatonin agonist and 5-hydroxytryptamine2C antagonist, already reported in the chronic mild stress and forced swimming tests, the effects of agomelatine were investigated in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed83aad75891a0930214eaffd6796749
https://doi.org/10.1097/fbp.0b013e3280116e5c
https://doi.org/10.1097/fbp.0b013e3280116e5c
Autor:
Pierre-Alain Boyer, Philippe Morain, Jean-Loïc Robin, Pierre Lestage, Guillaume De Nanteuil, David Guez, Roeline Jochemsen
Publikováno v:
CNS Drug Reviews. 8:31-52
Any treatment that could positively modulate central neuropeptides levels would provide a promising therapeutic approach to the treatment of cognitive deficits associated with aging and/or neurodegenerative diseases. Therefore, based on the activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfec7c8f989600d2e600951ce3ae689b
https://doi.org/10.1111/j.1527-3458.2002.tb00214.x
https://doi.org/10.1111/j.1527-3458.2002.tb00214.x
Publikováno v:
médecine/sciences. 21:888-894
There are now many potentials for the development of more effective, better tolerated, and more rapidly acting antidepressants acting in association and/or beyond the monoamine hypothesis. One of these possibilities is the development of antidepressa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d610bab3330cb265a8284289e6750c5
https://doi.org/10.1051/medsci/20052110888
https://doi.org/10.1051/medsci/20052110888
Publikováno v:
Neuropharmacology. 47:515-526
Agomelatine (S 20098) is a novel antidepressant drug with melatonin receptor agonist and 5-HT(2C) receptor antagonist properties, but actual mechanisms underlying its antidepressant action are unknown. Because functional desensitization of 5-HT(1A) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb769968d3931df327eecac163a0dd4a
https://doi.org/10.1016/j.neuropharm.2004.06.003
https://doi.org/10.1016/j.neuropharm.2004.06.003
Publikováno v:
Neuropsychopharmacology. 28:694-703
Chronic mild stress (CMS), a well-validated model of depression, was used to study the effects of the melatonin agonist and selective 5-HT2C antagonist agomelatine (S 20098) in comparison with melatonin, imipramine, and fluoxetine. All drugs were adm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e75fcc03135d0e74429db4a25f2522
https://doi.org/10.1038/sj.npp.1300091
https://doi.org/10.1038/sj.npp.1300091
Autor:
Eric Houdeau, Pierre-Alain Boyer
Publikováno v:
Cell and Tissue Research. 277:579-586
The distribution of mRNA encoding neuropeptide Y in cells of the rat pelvic paracervical ganglion was studied by the use of in situ hybridization with a neuropeptide Y oligodeoxynucleotide probe. The specificity of the hybridization signal was assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26ecaac3fa72c045363435ccc93c087e
https://doi.org/10.1007/bf00300232
https://doi.org/10.1007/bf00300232
Publikováno v:
Brain Research Bulletin. 33:541-560
In the present study, we describe the neurochemical effects of intranigral injections of colchicine in the rat forebrain using immunohistochemistry and in situ hybridization. The observations on the injected side are compared to the contralateral one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6eb1b70f6cfba73f1d8d7834350f6f
https://doi.org/10.1016/0361-9230(94)90081-7
https://doi.org/10.1016/0361-9230(94)90081-7
Publikováno v:
Brain Research Bulletin. 27:19-27
The use of a new and very sensitive immunohistochemical method, combined with intracerebral injections of colchicine, has allowed us to show that a number of nerve cell bodies immunoreactive for Met-enkephalin are present in several mesencephalic nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14506e76ac68a2135ad612e7787ef3ea
https://doi.org/10.1016/0361-9230(91)90275-o
https://doi.org/10.1016/0361-9230(91)90275-o
Publikováno v:
Medecine sciences : M/S. 21(10)
There are now many potentials for the development of more effective, better tolerated, and more rapidly acting antidepressants acting in association and/or beyond the monoamine hypothesis. One of these possibilities is the development of antidepressa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5899dc1095165e02c74848657ec2be77
https://pubmed.ncbi.nlm.nih.gov/16197911
https://pubmed.ncbi.nlm.nih.gov/16197911
Publikováno v:
Journal of molecular neuroscience : MN. 10(3)
Chronic administration of antidepressants produces region-specific adaptive changes in the radioligand binding properties of N-methyl-D-aspartate (NMDA) receptors. We hypothesized that this effect of chronic antidepressant administration was owing to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d2e28db4f531c04886fcb4d2d866af
https://pubmed.ncbi.nlm.nih.gov/9770644
https://pubmed.ncbi.nlm.nih.gov/9770644