In vivo characterization of dynein-driven nanovectors using Drosophila oocytes.

Autor: Nadège Parassol, Céline Bienvenu, Cécile Boglio, Sébastien Fiorucci, Delphine Cerezo, Xiao-Min Yu, Guilhem Godeau, Jacques Greiner, Pierre Vierling, Stéphane Noselli, Christophe Di Giorgio, Véronique Van De Bor

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e82908 (2013)

Molecular motors transport various cargoes including vesicles, proteins and mRNAs, to distinct intracellular compartments. A significant challenge in the field of nanotechnology is to improve drug nuclear delivery by engineering nanocarriers transpor

Externí odkaz: https://doaj.org/article/cbe7955472244aad90dc7f7e0169b054

Formulation of Highly Functionalizable DNA Nanoparticles Based on 1,2-Dithiolane Derivatives

Autor: Guilhem Godeau, Coralie Charrat, Anaïs Biscotti, Jean-Marie Guigonis, Pierre Vierling, Jacques Greiner, Christophe Di Giorgio

Publikováno v: ChemBioChem. 16:792-804

We describe the formulation of synthetic virus models based on ionic compounds bearing the polymerizable 1,2-dithiolane moiety. First, cationic amphiphiles containing the polymeric inducer were prepared and used to efficiently condense a DNA plasmid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8baf86ac7d2faea37d5c04340e08fda
https://doi.org/10.1002/cbic.201402657

Necrosis of HepG2 cancer cells induced by the vibration of magnetic particles

Autor: Christophe Di Giorgio, Pierre Vierling, Alexandra Madeira, Pascal Lançon, Georges Bossis, Biran Wang, Céline Bienvenu, Juan Mendez-Garza

Publikováno v: Journal of Magnetism and Magnetic Materials
Journal of Magnetism and Magnetic Materials, Elsevier, 2013, 344, pp.193-201. ⟨10.1016/j.jmmm.2013.05.043⟩

International audience; Experiments of magnetolysis, i.e., destruction of cells induced with magnetic particles (MPs) submitted to the application of a magnetic field, were conducted on HepG2 cancer cells. We herein demonstrate the usefulness of comb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed212c8b9c3bcbae17bd77286d33b4b4
https://doi.org/10.1016/j.jmmm.2013.05.043

Mannosyl-coated nanocomplexes from amphiphilic cyclodextrins and pDNA for site-specific gene delivery

Autor: Nicolas Guilloteau, José M. García Fernández, Christophe Di Giorgio, Jacques Defaye, Pierre Vierling, Juan M. Benito, Alejandro Méndez-Ardoy, Céline Bienvenu, José L. Jiménez Blanco, Alejandro Díaz-Moscoso, Carmen Ortiz Mellet, Loïc Le Gourriérec

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Fully homogeneous facial amphiphiles consisting in a cyclodextrin (CD) platform onto which a polycationic cluster and a multi-tail hydrophobic moiety have been installed (polycationic amphiphilic CDs; paCDs) self-organized in the presence of plasmid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4160a8af24d9f3fb973cd396a9e1799
https://doi.org/10.1016/j.biomaterials.2011.06.025

An efficient mixed solid–liquid phase synthesis of a heterobifunctional amphiphilic PEG–NH2 derivative and its conjugation to folic acid

Autor: Loïc Le Gourriérec, Pierre Vierling, Jacques Greiner, Christophe Di Giorgio

Publikováno v: Tetrahedron. 64:2233-2240

A very efficient, versatile as well as simple to perform procedure was developed in order to prepare a heterobifunctional amphiphilic PEG–NH 2 derivative which can be used for conjugation to a targeting ligand (such as folic acid). This method proc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::469efe217f8f48ab6dbdfc18037ceb43
https://doi.org/10.1016/j.tet.2007.12.027