Zobrazeno 1 - 10 of 56 pro vyhledávání: '"Pierre Vaigot"'
1
KLF4 inhibition promotes the expansion of keratinocyte precursors from adult human skin and of embryonic-stem-cell-derived keratinocytes
Autor: Paul-Henri Romeo, Michèle T. Martin, Jean-François Deleuze, Nicolas O. Fortunel, Sophie Domingues, Sophie Cavallero, Julien Coutier, Loubna Chadli, Frédéric Auvré, Emmanuelle Bouissou-Cadio, Gilles Lemaitre, Pierre Vaigot
Publikováno v: Nature biomedical engineering. 3(12)
Expanded autologous skin keratinocytes are currently used in cutaneous cell therapy, and embryonic-stem-cell-derived keratinocytes could become a complementary alternative. Regardless of keratinocyte provenance, for efficient therapy it is necessary
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf216dd340180f782b67d12a61173ca9
https://pubmed.ncbi.nlm.nih.gov/31636412
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2
FGF2 mediates DNA repair in epidermoid carcinoma cells exposed to ionizing radiation
Autor: Sandra Moratille, Mélanie Marie, Sophia Hafner, Odile Rigaud, Michèle T. Martin, Pierre Vaigot, Solène Mine
Publikováno v: International Journal of Radiation Biology
Purpose : Fibroblast growth factor 2 (FGF2) is a well-known survival factor. However, its role in DNA repair is poorly documented. The present study was designed to investigate in epidermoid carcinoma cells the potential role of FGF2 in DNA repair. M
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef567bf15ccc433a9659e2cf929230c5
http://europepmc.org/articles/PMC3477890
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3
CD98hc (SLC3A2) is a key regulator of keratinocyte adhesion
Autor: Michèle T. Martin, Gilles Waksman, Jessica Feteira, Christine Baldeschi, Alexandre Stella, Pierre Vaigot, Bernard Monsarrat, Gilles Lemaitre
Publikováno v: Journal of Dermatological Science. 61:169-179
Background Adhesion of keratinocytes is crucial for maintaining the integrity of the skin, as demonstrated by the number of dermatological disorders of genetic origin that are associated with a defect of basal keratinocyte adhesion. Integrins are the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775244ce272132ff671a2b3e81a436fe
https://doi.org/10.1016/j.jdermsci.2010.12.007
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4
Exploration of the functional hierarchy of the basal layer of human epidermis at the single-cell level using parallel clonal microcultures of keratinocytes
Autor: Nicolas O. Fortunel, Stephan Bouet, Emmanuelle Cadio, Paul-Henri Romeo, Loubna Chadli, Pierre Vaigot, Michèle T. Martin, Sandra Moratille
Publikováno v: Experimental Dermatology
Experimental Dermatology, Wiley, 2010, 19 (4), pp.387-392. ⟨10.1111/j.1600-0625.2009.01046.x⟩
Experimental Dermatology, 2010, 19 (4), pp.387-392. ⟨10.1111/j.1600-0625.2009.01046.x⟩
Chantier qualité GA; International audience; The basal layer of human epidermis contains both stem cells and keratinocyte progenitors. Because of this cellular heterogeneity, the development of methods suitable for investigations at a clonal level i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8411a957814a37e596206db9d418886
https://doi.org/10.1111/j.1600-0625.2009.01046.x
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5
Single thrombopoietin dose alleviates hematopoietic stem cells intrinsic short- and long-term ionizing radiation damage. In vivo identification of anatomical cell expansion sites
Autor: Paquita Nurden, Diana Tronik-Le Roux, Pierre Vaigot, Marie-Anne Nicola
Publikováno v: Radiation research. 183(1)
Hematopoietic stem cells (HSC) are essential for maintaining the integrity of complex and long-lived organisms. HSC, which are self-renewing, reconstitute the hematopoietic system through out life and facilitate long-term repopulation of myeloablated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f5952d2595793718faeb859fd29daa
https://pubmed.ncbi.nlm.nih.gov/25564715
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6
Expression profiling of genes and proteins in HaCaT keratinocytes: Proliferating versus differentiated state
Autor: Cyrille Petat, Pierre Vaigot, Amandine Pitaval, Pascal Soularue, Gilles Lemaitre, Jérôme Garin, Michèle T. Martin, Xavier Gidrol, Stephan Bouet, Jérôme Lamartine, Gilles Waksman
Publikováno v: Journal of Cellular Biochemistry. 93:1048-1062
The knowledge of the mechanism of keratinocyte differentiation in culture is still uncompleted. The emergence of new technologies, such as cDNA microarrays or 2D electrophoresis followed by mass spectrometry analysis, has allowed the identification o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4f9d35c58f4e9ac6cd59f52e4143e48
https://doi.org/10.1002/jcb.20212
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7
Endothelin 3 induces the reversion of melanocytes to glia through a neural crest-derived glial-melanocytic progenitor
Autor: Pierre Vaigot, Corinne Glavieux, Elisabeth Dupin, Nicole M. Le Douarin
Publikováno v: Proceedings of the National Academy of Sciences. 97:7882-7887
Functional signaling of endothelin 3 (ET3) and its receptor B (ETRB) has been shown to be required for the development of neural crest (NC)-derived pigment cells in mouse, but the precise role of ET3 is not completely understood. Using the avian embr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4bc15ae181cc2d44ff446dc886c981
https://doi.org/10.1073/pnas.97.14.7882
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8
Glycoprotein IIb-IIIa Is Expressed on Avian Multilineage Hematopoietic Progenitor Cells
Autor: Christiane Ody, Catherine Corbel, Pierre Vaigot, Beat A. Imhof, Pascale Quéré
Publikováno v: Blood. 93:2898-2906
The fibrinogen receptor GPIIb-IIIa integrin is known to be expressed on cells of the megakaryocytic lineage, but its presence on hematopoietic progenitors has been a controversial issue. To resolve this ambiguity unequivocally, we performed clonogeni
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::46868b4fe1b9c6f63e10667072c20ce8
https://doi.org/10.1182/blood.v93.9.2898
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9
Ligand-dependent development of the endothelial and hemopoietic lineages from embryonic mesodermal cells expressing vascular endothelial growth factor receptor 2
Autor: Catherine Corbel, Pierre Vaigot, Christiane Bréant, Anne Eichmann, V. Nataf, Nicole M. Le Douarin
Publikováno v: Proceedings of the National Academy of Sciences. 94:5141-5146
The existence of a common precursor for endothelial and hemopoietic cells, termed the hemangioblast, has been postulated since the beginning of the century. Recently, deletion of the endothelial-specific vascular endothelial growth factor receptor 2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7a4791f436f778a967d051c860aee8
https://doi.org/10.1073/pnas.94.10.5141
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10
Monitoring the cycling activity of cultured human keratinocytes using a CFSE-based dye tracking approach
Autor: Loubna, Chadli, Emmanuelle, Cadio, Pierre, Vaigot, Michèle T, Martin, Nicolas O, Fortunel
Publikováno v: Methods in molecular biology (Clifton, N.J.). 989
The development of methods and tools suitable for functional analysis of keratinocytes placed in an in vitro context is of great importance for characterizing properties associated with their normal state, for detecting abnormalities related to patho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5332520458616242e0392db2e6db54a2
https://pubmed.ncbi.nlm.nih.gov/23483389
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